Finding the characterized proteins for hisD (histidinal/histidinol dehydrogenase) in L-histidine biosynthesis
Or see clustering for step hisD
Or see all steps for L-histidine biosynthesis
Or cluster curated proteins matching a keyword
Definition of hisD
Fetched 9 sequences
Running ublast to find other characterized proteins with 40% identity and 70% coverage
Found hits to 1 other characterized sequences. (Found 10 hits including self hits.)
Removing ignored items reduces this to 0 close sequences.
There are also 1 HMM-only high-coverage hits.
(Since these sequences' annotations are outside the definition for hisD, HMM hits that are over 40% similar to these sequences will be scored as moderate confidence.)
Q46N53 sulfopropanediol 3-dehydrogenase monomer (EC 1.1.1.308) from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197)
HPSN_CUPPJ / Q46N53 Sulfopropanediol 3-dehydrogenase; 2,3-dihydroxypropane-1-sulfonate 3-dehydrogenase (sulfolactate forming); DHPS 3-dehydrogenase (sulfolactate forming); EC 1.1.1.308 from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Cupriavidus necator (strain JMP 134))
Q46N53 sulfopropanediol 3-dehydrogenase (EC 1.1.1.308) from Cupriavidus pinatubonensis
PFams: Histidinol_dh
436 amino acids: PaperBLAST, CDD
(Sequences that are similar to these will still be high-confidence candidates for hisD.)
CH_123581 multifunctional enzyme that catalyzes three steps of histidine biosynthesis from Candida albicans
PFams: PRA-CH, PRA-PH, Histidinol_dh
838 amino acids: PaperBLAST, CDD, CharProtDB::CH_123581
56% identical to
A1BPP9 histidinol dehydrogenase (EC 1.1.1.23) from Geotrichum candidum
PFams: PRA-CH, PRA-PH, Histidinol_dh
844 amino acids: PaperBLAST, CDD