GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for hisE (phosphoribosyl-AMP cyclohydrolase) in L-histidine biosynthesis

Or see other characterized proteins similar to hisE

Or see all steps for L-histidine biosynthesis

Or cluster curated proteins matching a keyword

Definition of hisE

Fetched 7 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 4 of these sequences

Found 2 clusters of similar sequences. Another 3 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 136-138 amino acids (not heteromeric)

Q50837 Phosphoribosyl-AMP cyclohydrolase; PRA-CH; EC 3.5.4.19
Q50837 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)
PFams: PRA-CH
136 amino acids: PaperBLAST, CDD, Compare to cluster

O26347 Phosphoribosyl-AMP cyclohydrolase; PRA-CH; EC 3.5.4.19
PFams: PRA-CH
138 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 799-844 amino acids (not heteromeric)

A1BPP9 histidinol dehydrogenase (EC 1.1.1.23) (from HMM only)
PFams: PRA-CH, PRA-PH, Histidinol_dh
844 amino acids: PaperBLAST, CDD, Compare to cluster

P00815 Histidine biosynthesis trifunctional protein; EC 3.5.4.19; EC 3.6.1.31; EC 1.1.1.23
PFams: PRA-CH, PRA-PH, Histidinol_dh
799 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/3 heteromeric)

O59667 Histidine biosynthesis bifunctional protein his7; EC 3.5.4.19; EC 3.6.1.31
CH_124755 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase His7; EC 3.5.4.19; EC 3.6.1.31
PFams: PRA-CH, PRA-PH
417 amino acids: PaperBLAST, CDD

AT1G31860-MONOMER phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19; EC 3.6.1.31)
O82768 Histidine biosynthesis bifunctional protein hisIE, chloroplastic; Protein HISTIDINE BIOSYNTHESIS 2; EC 3.5.4.19; EC 3.6.1.31
PFams: PRA-CH, PRA-PH, MazG
281 amino acids: PaperBLAST, CDD

HISTCYCLOPRATPPHOS putative bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase (EC 3.5.4.19; EC 3.6.1.31)
HISTCYCLOPRATPPHOS phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19; EC 3.6.1.31)
PFams: PRA-CH, PRA-PH
203 amino acids: PaperBLAST, CDD