Clusters of Characterized Proteins

Clustering the characterized proteins for hisH (imidazole glycerol phosphate synthase, amidotransferase subunit) in L-histidine biosynthesis

Or see other characterized proteins similar to hisH

Or see all steps for L-histidine biosynthesis

Or cluster curated proteins matching a keyword

Definition of hisH

• Curated proteins matching hisH
• Curated proteins matching IGP synthase, amidotransferase subunit
• HMM TIGR01855
• Ignore hits to items matching imidazole glycerol phosphate synthase when looking for 'other' hits
• Curated sequence Q5NMD4: imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10)
• Curated sequence Q8ZY40: imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10)
• Curated sequence Q9SZ30: imidazole glycerol-phosphate synthase (EC 4.3.2.10). imidazole-glycerol-phosphate synthase (EC 4.3.2.10)
• Curated sequence A4WHA5: imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10)
• Comment: Subunits are not always annotated consistently, so are added manually, and Q9SZ30 is a fusion protein of the two subunits

Fetched 11 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 10 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by cluster

Arabidopsis thaliana

Q9SZ30 imidazole-glycerol-phosphate synthase (EC 4.3.2.10) from Arabidopsis thaliana
Q9SZ30 imidazole glycerol-phosphate synthase (EC 4.3.2.10) from Arabidopsis thaliana
PFams: GATase, GATase_3, His_biosynth
592 amino acids: PaperBLAST, CDD (Singleton 1)

Desulfovibrio vulgaris

DVU0285 IGP synthase, amidotransferase subunit (EC 4.3.2.10) from Desulfovibrio vulgaris Hildenborough JW710
PFams: GATase
Heteromeric, 213 amino acids: PaperBLAST, CDD (Cluster 1)

DvMF_2305 IGP synthase, amidotransferase subunit (EC 4.3.2.10) from Desulfovibrio vulgaris Miyazaki F
PFams: GATase
Heteromeric, 212 amino acids: PaperBLAST, CDD (Cluster 1)

Escherichia coli

b2023 imidazole glycerol phosphate synthase subunit HisH (EC 4.3.2.10) from Escherichia coli K-12 substr. MG1655
P60595 imidazole glycerol phosphate synthase subunit HisH (EC 4.3.2.10) from Escherichia coli (strain K12)
HIS5_ECOLI / P60595 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; EC 4.3.2.10; EC 3.5.1.2 from Escherichia coli (strain K12)
RF|NP_416527 IGP synthase glutamine amidotransferase subunit; EC 2.4.2.- from Escherichia coli K12
PFams: GATase
Heteromeric, 196 amino acids: PaperBLAST, CDD (Cluster 1)

Herbaspirillum seropedicae

HSERO_RS20325 IGP synthase, amidotransferase subunit (EC 4.3.2.10) from Herbaspirillum seropedicae SmR1
PFams: GATase
Heteromeric, 212 amino acids: PaperBLAST, CDD (Cluster 1)

Mycobacterium bovis

HIS5_MYCBO / P59957 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; EC 4.3.2.10; EC 3.5.1.2 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
PFams: GATase
Heteromeric, 206 amino acids: PaperBLAST, CDD (Cluster 1)

Pyrobaculum aerophilum

Q8ZY40 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Pyrobaculum aerophilum
PFams: GATase
Heteromeric, 190 amino acids: PaperBLAST, CDD (Cluster 1)

Pyrobaculum arsenaticum

A4WHA5 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Pyrobaculum arsenaticum
PFams: GATase, SNO
Heteromeric, 191 amino acids: PaperBLAST, CDD (Cluster 1)

Thermotoga maritima

Q9X0C8 imidazole-glycerol-phosphate synthase glutamine amidotransferase subunit (EC 4.3.2.10) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
HIS5_THEMA / Q9X0C8 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; TmHisH; EC 4.3.2.10; EC 3.5.1.2 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Q9X0C8 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Thermotoga maritima
PFams: GATase_3, GATase
Heteromeric, 201 amino acids: PaperBLAST, CDD (Cluster 1)

Thermus thermophilus

HIS5_THET8 / Q7SIC0 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; EC 4.3.2.10; EC 3.5.1.2 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Q7SIC0 imidazole glycerol-phosphate synthase (subunit 2/2) (EC 4.3.2.10) from Thermus thermophilus
PFams: GATase, SNO, GATase_3
Heteromeric, 200 amino acids: PaperBLAST, CDD (Cluster 1)

Zymomonas mobilis

Q5NMD4 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Zymomonas mobilis
PFams: GATase
Heteromeric, 213 amino acids: PaperBLAST, CDD (Cluster 1)