Clusters of Characterized Proteins

GapMind for Amino acid biosynthesis

Clusters of Characterized Proteins

Clustering the characterized proteins for hisN (histidinol-phosphate phosphatase) in L-histidine biosynthesis

Or see other characterized proteins similar to hisN

Or see all steps for L-histidine biosynthesis

Or cluster curated proteins matching a keyword

Definition of hisN

Curated proteins or TIGRFams with EC 3.1.3.15
UniProt sequence B9E9Z0_MACCJ: RecName: Full=Histidinol-phosphatase {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}; Short=HolPase {ECO:0000256|RuleBase:RU366003}; EC=3.1.3.15 {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003};
UniProt sequence C0ZH63_BREBN: RecName: Full=Histidinol-phosphatase {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}; Short=HolPase {ECO:0000256|RuleBase:RU366003}; EC=3.1.3.15 {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003};
UniProt sequence Q73B87_BACC1: RecName: Full=Histidinol-phosphatase {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}; Short=HolPase {ECO:0000256|RuleBase:RU366003}; EC=3.1.3.15 {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003};
UniProt sequence A9VLI0_BACWK: RecName: Full=Histidinol-phosphatase {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}; Short=HolPase {ECO:0000256|RuleBase:RU366003}; EC=3.1.3.15 {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003};
UniProt sequence HIS9_BACHD: RecName: Full=Histidinol-phosphatase; Short=HolPase; EC=3.1.3.15;
UniProt sequence Q5KW52_GEOKA: RecName: Full=Histidinol-phosphatase {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}; Short=HolPase {ECO:0000256|RuleBase:RU366003}; EC=3.1.3.15 {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003};
UniProt sequence Q8DT80_STRMU: RecName: Full=Histidinol-phosphatase {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}; Short=HolPase {ECO:0000256|RuleBase:RU366003}; EC=3.1.3.15 {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003};
UniProt sequence HIS9_BACSU: RecName: Full=Histidinol-phosphatase; Short=HolPase; EC=3.1.3.15;
Comment: In Bacillus subtilis and some related bacteria, histidinol-phosphate phosphatase is known as HisJ and has been confirmed by biochemical assays of purified proteins (PMC3570733). The identifiers given (see their Table 3) are MCCL_0344 BBR47_00270 BCE_1533 BcerKBAB4_1335 BcerKBAB4_1335 BSU29620 BH3206 GK2799 SMU_1486c (B9E9Z0_MACCJ C0ZH63_BREBN Q73B87_BACC1 A9VLI0_BACWK HIS9_BACHD Q5KW52_GEOKA Q8DT80_STRMU HIS9_BACSU).

Fetched 28 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 22 of these sequences

Found 6 clusters of similar sequences. Another 6 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 250-266 amino acids (not heteromeric)

Q8NS80 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15
Q8NS80 histidinol-phosphatase (EC 3.1.3.15)
PFams: Inositol_P
260 amino acids: PaperBLAST, CDD, Compare to cluster

P95189 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15
PFams: Inositol_P
260 amino acids: PaperBLAST, CDD, Compare to cluster

Q9K4B1 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15
PFams: Inositol_P
266 amino acids: PaperBLAST, CDD, Compare to cluster

Korea:Ga0059261_2035 Histidinol-phosphatase [alternative form] (EC 3.1.3.15)
PFams: Inositol_P
260 amino acids: PaperBLAST, CDD, Compare to cluster

Phaeo:GFF2154 Histidinol-phosphatase [alternative form] (EC 3.1.3.15)
PFams: Inositol_P
250 amino acids: PaperBLAST, CDD, Compare to cluster

azobra:AZOBR_RS03845 Histidinol-phosphatase [alternative form] (EC 3.1.3.15)
PFams: Inositol_P
260 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 334-339 amino acids (not heteromeric)

A9VLI0_BACWK Histidinol-phosphatase {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}; Short=HolPase {ECO:0000256|RuleBase:RU366003}; EC=3.1.3.15 {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}
339 amino acids: PaperBLAST, CDD, Compare to cluster

B9E9Z0_MACCJ Histidinol-phosphatase {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}; Short=HolPase {ECO:0000256|RuleBase:RU366003}; EC=3.1.3.15 {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}
335 amino acids: PaperBLAST, CDD, Compare to cluster

C0ZH63_BREBN Histidinol-phosphatase {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}; Short=HolPase {ECO:0000256|RuleBase:RU366003}; EC=3.1.3.15 {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}
334 amino acids: PaperBLAST, CDD, Compare to cluster

Q73B87_BACC1 Histidinol-phosphatase {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}; Short=HolPase {ECO:0000256|RuleBase:RU366003}; EC=3.1.3.15 {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}
338 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 355-382 amino acids (not heteromeric)

D2QPE6 Histidine biosynthesis bifunctional protein HisB; EC 3.1.3.15; EC 4.2.1.19
PFams: PNK3P, Hydrolase_like, IGPD
382 amino acids: PaperBLAST, CDD, Compare to cluster

Q8ABA7 Histidine biosynthesis bifunctional protein HisB; EC 3.1.3.15; EC 4.2.1.19
PFams: Hydrolase_like, IGPD
374 amino acids: PaperBLAST, CDD, Compare to cluster

Q9S5G5 Histidine biosynthesis bifunctional protein HisB; EC 3.1.3.15; EC 4.2.1.19
PFams: PNK3P, Hydrolase_like, IGPD
355 amino acids: PaperBLAST, CDD, Compare to cluster

IMIDPHOSPHADEHYDHISTIDPHOSPHA-MONOMER imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase (EC 4.2.1.19; EC 3.1.3.15)
PFams: PNK3P, Hydrolase_like, IGPD
355 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 217-228 amino acids (not heteromeric)

BFirm:BPHYT_RS03625 Histidinol-phosphatase (EC:3.1.3.15)
PFams: HAD
228 amino acids: PaperBLAST, CDD, Compare to cluster

Marino:GFF473 Histidinol-phosphatase (EC:3.1.3.15)
PFams: HAD
218 amino acids: PaperBLAST, CDD, Compare to cluster

psRCH2:GFF3795 Histidinol-phosphatase (EC:3.1.3.15)
PFams: HAD
217 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 5 268-274 amino acids (not heteromeric)

HIS9_BACHD Histidinol-phosphatase; Short=HolPase; EC=3.1.3.15
273 amino acids: PaperBLAST, CDD, Compare to cluster

HIS9_BACSU Histidinol-phosphatase; Short=HolPase; EC=3.1.3.15
268 amino acids: PaperBLAST, CDD, Compare to cluster

Q5KW52_GEOKA Histidinol-phosphatase {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}; Short=HolPase {ECO:0000256|RuleBase:RU366003}; EC=3.1.3.15 {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}
274 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 6 199-217 amino acids (not heteromeric)

S5FT07 Carbon disulfide hydrolase; CS(2) hydrolase; EC 3.13.1.5
S5FT07 histidinol-phosphatase (EC 3.1.3.15)
PFams: Pro_CA
217 amino acids: PaperBLAST, CDD, Compare to cluster

S5FU55 Carbon disulfide hydrolase; CS(2) hydrolase; EC 3.13.1.5
S5FU55 histidinol-phosphatase (EC 3.1.3.15)
PFams: Pro_CA
199 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/6 heteromeric)

B1PRL6 histidinol-phosphatase (EC 3.1.3.15)
240 amino acids: PaperBLAST, CDD

ALKAPHOSPHA-MONOMER alkaline phosphatase (EC 3.1.3.1; EC 3.1.3.75; EC 3.1.3.41; EC 3.1.3.74; EC 3.1.3.99; EC 3.1.3.5; EC 3.1.3.6; EC 3.1.3.89; EC 3.1.3.91; EC 3.1.3.60; EC 3.1.3.15; EC 3.1.3.102; EC 3.1.3.2; EC 3.1.3.11; EC 3.1.3.20; EC 3.1.3.19; EC 3.1.3.3; EC 3.6.1.25; EC 3.6.1.1; EC 3.1.3.58; EC 3.1.3.9; EC 3.1.3.23; EC 3.1.3.38; EC 3.1.3.18; EC 3.1.3.68; EC 3.9.1.1)
P00634 alkaline phosphatase (EC 3.1.3.1)
ALKAPHOSPHA-MONOMER alkaline phosphatase (EC 3.1.3.1; EC 3.1.3.75; EC 3.1.3.41; EC 3.1.3.74; EC 3.1.3.99; EC 3.1.3.5; EC 3.1.3.6; EC 3.1.3.89; EC 3.1.3.91; EC 3.1.3.60; EC 3.1.3.15; EC 3.1.3.102; EC 3.1.3.2; EC 3.1.3.11; EC 3.1.3.20; EC 3.1.3.19; EC 3.1.3.3; EC 3.6.1.25; EC 3.6.1.1; EC 3.1.3.58; EC 3.1.3.23; EC 3.1.3.38; EC 3.1.3.18; EC 3.1.3.68; EC 3.9.1.1)
PFams: Alk_phosphatase, Metalloenzyme, Alk_phosphatase
471 amino acids: PaperBLAST, CDD

Q02150 histidinol-phosphatase (EC 3.1.3.15)
PFams: PHP
269 amino acids: PaperBLAST, CDD

Q6NPM8 Bifunctional phosphatase IMPL2, chloroplastic; Histidinol-phosphatase; Histidinol-phosphate phosphatase; HPP; Inositol-phosphate phosphatase; L-galactose 1-phosphate phosphatase; Protein HISTIDINE BIOSYNTHESIS 7; Protein MYO-INOSITOL MONOPHOSPHATASE-LIKE 2; EC 3.1.3.15; EC 3.1.3.25; EC 3.1.3.93
Q6NPM8 histidinol-phosphatase (EC 3.1.3.15); inositol-phosphate phosphatase (EC 3.1.3.25)
AT4G39120-MONOMER histidinol-phosphate phosphatase (EC 3.1.3.15; EC 3.1.3.93; EC 3.1.3.25)
PFams: Inositol_P
346 amino acids: PaperBLAST, CDD

P38635 Histidinol-phosphatase; HolPase; EC 3.1.3.15
PFams: PHP
335 amino acids: PaperBLAST, CDD

Q8DT80_STRMU Histidinol-phosphatase {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}; Short=HolPase {ECO:0000256|RuleBase:RU366003}; EC=3.1.3.15 {ECO:0000256|ARBA:ARBA00013085, ECO:0000256|RuleBase:RU366003}
244 amino acids: PaperBLAST, CDD