GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for ilvH (acetolactate/acetohydroxybutanoate synthase regulatory subunit ) in L-isoleucine biosynthesis

Or see other characterized proteins similar to ilvH

Or see all steps for L-isoleucine biosynthesis

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Definition of ilvH

Fetched 14 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 12 of these sequences

Found 4 clusters of similar sequences. Another 2 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 449-491 amino acids (not heteromeric)

ILVH2_ARATH / Q9FFF4 Acetolactate synthase small subunit 2, chloroplastic; ALS-interacting protein 3; Acetohydroxy-acid synthase small subunit 2; Protein valine-tolerant 1 from Arabidopsis thaliana (Mouse-ear cress)
PFams: ACT, ACT_5, ALS_ss_C, ACT, ACT_5, ALS_ss_C
477 amino acids: PaperBLAST, CDD, Compare to cluster

ILVH1_ARATH / Q93YZ7 Acetolactate synthase small subunit 1, chloroplastic; ALS-interacting protein 1; Acetohydroxyacid synthase small subunit 1 from Arabidopsis thaliana (Mouse-ear cress)
PFams: ACT, ACT_5, ALS_ss_C, ACT, ACT_5, ALS_ss_C
491 amino acids: PaperBLAST, CDD, Compare to cluster

ILVH_NICPL / Q9SMC2 Acetolactate synthase small subunit 1, chloroplastic; Acetohydroxy-acid synthase small subunit; AHAS; ALS from Nicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco)
PFams: ACT_5, ACT, ALS_ss_C, ACT, ACT_5, ALS_ss_C
449 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 289-326 amino acids (not heteromeric)

CH_122620 small subunit of acetolactate synthase from Emericella nidulans
PFams: ACT, ACT_5, ALS_ss_C
326 amino acids: PaperBLAST, CDD, Compare to cluster

ILV6_SCHPO / O60086 Probable acetolactate synthase small subunit; Acetohydroxy-acid synthase small subunit; AHAS; ALS from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
PFams: ACT, ACT_5, ALS_ss_C
289 amino acids: PaperBLAST, CDD, Compare to cluster

ILV6_YEAST / P25605 Acetolactate synthase small subunit, mitochondrial; Acetohydroxy-acid synthase small subunit; AHAS; ALS from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: ACT, ACT_5, ALS_ss_C
309 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 163-169 amino acids (heteromeric)

b0078 acetolactate synthase / acetohydroxybutanoate synthase, regulatory subunit (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655
P00894 acetolactate synthase / acetohydroxybutanoate synthase, regulatory subunit (EC 2.2.1.6) from Escherichia coli (strain K12)
P00894 acetolactate synthase (subunit 1/2) (EC 2.2.1.6) from Escherichia coli
GB|BAB96647.2 acetolactate synthase, small subunit; EC 2.2.1.6 from Escherichia coli
PFams: ACT, ACT_5, ALS_ss_C
Heteromeric, 163 amino acids: PaperBLAST, CDD, Compare to cluster

ILVH_MYCTU / P9WKJ3 Putative acetolactate synthase small subunit; Acetohydroxy-acid synthase small subunit; AHAS; ALS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WKJ3 acetolactate synthase (subunit 1/2) (EC 2.2.1.6) from Mycobacterium tuberculosis
PFams: ACT, ACT_5, ALS_ss_C
Heteromeric, 168 amino acids: PaperBLAST, CDD, Compare to cluster

O08354 acetohydroxy-acid synthase small subunit (EC 2.2.1.6) from Methanococcus aeolicus
PFams: ACT, ACT_5, ALS_ss_C
Heteromeric, 169 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 82-87 amino acids (not heteromeric)

A0A0H2X4P1 Acetolactate synthase isozyme II small subunit
85 amino acids: PaperBLAST, CDD, Compare to cluster

b3769 acetolactate synthase II subunit IlvM (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655
P0ADG1 acetolactate synthase (subunit 1/2) (EC 2.2.1.6) from Escherichia coli
PFams: ACT_5
87 amino acids: PaperBLAST, CDD, Compare to cluster

A0A154R0Y7 Acetolactate synthase small subunit {ECO:0000256|RuleBase:RU368092}; Short=AHAS {ECO:0000256|RuleBase:RU368092}; Short=ALS {ECO:0000256|RuleBase:RU368092}; EC=2.2.1.6 {ECO:0000256|RuleBase:RU368092}; Acetohydroxy-acid synthase small subunit {ECO:0000256|RuleBase:RU368092}
82 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/2 heteromeric)

A0A161J739 Acetolactate synthase 3 regulatory subunit domain protein
83 amino acids: PaperBLAST, CDD

A0A7J3AYJ4 Uncharacterized protein
88 amino acids: PaperBLAST, CDD