Clusters of Characterized Proteins

Clustering the characterized proteins for ilvI (acetohydroxybutanoate synthase regulatory subunit ) in L-isoleucine biosynthesis

Or see other characterized proteins similar to ilvI

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Or cluster curated proteins matching a keyword

Definition of ilvI

• HMM TIGR00119
• Curated proteins matching acetohydroxy-acid synthase%small
• Curated proteins matching acetohydroxybutanoate synthase, regulatory subunit
• Curated proteins matching small subunit of acetolactate synthase
• Ignore hits to items matching EC 2.2.1.6 when looking for 'other' hits
• Comment: The isolated catalytic subunit has some activity so it's not clear if the regulatory subunit should be required.

Fetched 9 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 8 of these sequences

Found 3 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 289-326 amino acids (not heteromeric)

CH_122620 small subunit of acetolactate synthase
PFams: ACT, ACT_5, ALS_ss_C
326 amino acids: PaperBLAST, CDD, Compare to cluster

O60086 Probable acetolactate synthase small subunit; Acetohydroxy-acid synthase small subunit; AHAS; ALS
PFams: ACT, ACT_5, ALS_ss_C
289 amino acids: PaperBLAST, CDD, Compare to cluster

P25605 Acetolactate synthase small subunit, mitochondrial; Acetohydroxy-acid synthase small subunit; AHAS; ALS
PFams: ACT, ACT_5, ALS_ss_C
309 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 449-491 amino acids (not heteromeric)

Q9FFF4 Acetolactate synthase small subunit 1, chloroplastic; Acetohydroxy-acid synthase small subunit; AHAS; ALS; Protein valine-tolerant 1
PFams: ACT, ACT_5, ALS_ss_C, ACT, ACT_5, ALS_ss_C
477 amino acids: PaperBLAST, CDD, Compare to cluster

Q93YZ7 Acetolactate synthase small subunit 2, chloroplastic; Acetohydroxy-acid synthase small subunit; AHAS; ALS
PFams: ACT, ACT_5, ALS_ss_C, ACT, ACT_5, ALS_ss_C
491 amino acids: PaperBLAST, CDD, Compare to cluster

Q9SMC2 Acetolactate synthase small subunit 1, chloroplastic; Acetohydroxy-acid synthase small subunit; AHAS; ALS
PFams: ACT_5, ACT, ALS_ss_C, ACT, ACT_5, ALS_ss_C
449 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 163-168 amino acids (heteromeric)

ACETOLACTSYNIII-HCHAIN-MONOMER acetolactate synthase / acetohydroxybutanoate synthase, regulatory subunit (EC 2.2.1.6)
P00894 acetolactate synthase (subunit 1/2) (EC 2.2.1.6)
ACETOLACTSYNIII-HCHAIN-MONOMER acetolactate synthase / acetohydroxybutanoate synthase, regulatory subunit (EC 2.2.1.6)
CH_002163 acetolactate synthase, small subunit; EC 2.2.1.6
PFams: ACT, ACT_5, ALS_ss_C
Heteromeric, 163 amino acids: PaperBLAST, CDD, Compare to cluster

P9WKJ3 Putative acetolactate synthase small subunit; Acetohydroxy-acid synthase small subunit; AHAS; ALS; EC 2.2.1.6
P9WKJ3 acetolactate synthase (subunit 1/2) (EC 2.2.1.6)
PFams: ACT, ACT_5, ALS_ss_C
Heteromeric, 168 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

SMALLILVM-MONOMER acetolactate synthase II subunit IlvM (EC 2.2.1.6)
P0ADG1 acetolactate synthase (subunit 1/2) (EC 2.2.1.6)
SMALLILVM-MONOMER acetolactate synthase / acetohydroxybutanoate synthase, regulatory subunit (EC 2.2.1.6)
PFams: ACT_5
87 amino acids: PaperBLAST, CDD