GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for prpE (propionyl-CoA synthetase) in L-isoleucine biosynthesis

Or see other characterized proteins similar to prpE

Or see all steps for L-isoleucine biosynthesis

Or cluster curated proteins matching a keyword

Definition of prpE

Fetched 8 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 7 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 564-661 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

A4YGR1 3-hydroxypropionyl-coenzyme A synthetase; 3-hydroxypropionyl-CoA synthetase; EC 6.2.1.36
A4YGR1 propionate-CoA ligase (EC 6.2.1.17); 3-hydroxypropionyl-CoA synthase (EC 6.2.1.36)
PFams: ACAS_N, AMP-binding, AMP-binding_C
661 amino acids: PaperBLAST, CDD, Compare to cluster

MONOMER-13735 4-hydroxybutyryl-CoA synthetase (AMP-forming) (EC 6.2.1.40)
A4YDT1 4-hydroxybutyrate--CoA ligase 1; Acetate--CoA ligase; Butyrate--CoA ligase; Propionate--CoA ligase; EC 6.2.1.40; EC 6.2.1.1; EC 6.2.1.2; EC 6.2.1.17
A4YDT1 4-hydroxybutyrate-CoA ligase (EC 6.2.1.40)
PFams: AMP-binding, AMP-binding_C
564 amino acids: PaperBLAST, CDD, Compare to cluster

ACS-MONOMER acetyl-CoA synthetase (AMP-forming) (EC 6.2.1.1; EC 6.2.1.17)
ACS-MONOMER acetyl-CoA synthetase (AMP-forming) (EC 6.2.1.17; EC 6.2.1.1)
P27550 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1
PFams: ACAS_N, AMP-binding, AMP-binding_C
652 amino acids: PaperBLAST, CDD, Compare to cluster

MONOMER-13637 acetyl-CoA synthetase (EC 6.2.1.1; EC 6.2.1.17)
P31638 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1
PFams: ACAS_N, AMP-binding, AMP-binding_C
660 amino acids: PaperBLAST, CDD, Compare to cluster

MONOMER-62 propionate-CoA ligase (EC 6.2.1.17)
P55912 Propionate--CoA ligase; Propionyl-CoA synthetase; EC 6.2.1.17
PFams: ACAS_N, AMP-binding, AMP-binding_C
628 amino acids: PaperBLAST, CDD, Compare to cluster

G6200-MONOMER propionyl-CoA synthetase (EC 6.2.1.17)
G6200-MONOMER propionyl-CoA synthetase (EC 6.2.1.17)
PFams: ACAS_N, AMP-binding, AMP-binding_C
628 amino acids: PaperBLAST, CDD, Compare to cluster

Phaeo:GFF1175 Propionate--CoA ligase (EC 6.2.1.17)
PFams: ACAS_N, AMP-binding, AMP-binding_C
629 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

A4YDR9 4-hydroxybutyrate--CoA ligase 2; Acetate--CoA ligase; Butyrate--CoA ligase; Propionate--CoA ligase; acyl-activating enzyme; EC 6.2.1.40; EC 6.2.1.1; EC 6.2.1.2; EC 6.2.1.17
A4YDR9 4-hydroxybutyrate-CoA ligase (EC 6.2.1.40)
PFams: AMP-binding, AMP-binding_C
549 amino acids: PaperBLAST, CDD