GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for ilvC (ketol-acid reductoisomerase) in L-leucine biosynthesis

Or see other characterized proteins similar to ilvC

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Definition of ilvC

Fetched 30 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 30 of these sequences

Found 3 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 329-400 amino acids (not heteromeric)

A0A0K2AZ61 ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: 2-Hacid_dh_C, IlvN, F420_oxidored, NAD_binding_2, IlvC
332 amino acids: PaperBLAST, CDD, Compare to cluster

A6UW80 ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: IlvN, F420_oxidored, NAD_binding_2, IlvC
329 amino acids: PaperBLAST, CDD, Compare to cluster

C1DFH7 Ketol-acid reductoisomerase (NADP(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.86
C1DFH7 ketol-acid reductoisomerase [NAD(P)+] (EC 1.1.1.383); ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: 2-Hacid_dh_C, IlvN, F420_oxidored, NAD_binding_2, IlvC
338 amino acids: PaperBLAST, CDD, Compare to cluster

C8WR67 Ketol-acid reductoisomerase (NADP(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.86
C8WR67 ketol-acid reductoisomerase (NAD+) (EC 1.1.1.382); ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: 2-Hacid_dh_C, AdoHcyase_NAD, IlvN, F420_oxidored, NAD_binding_2, IlvC
344 amino acids: PaperBLAST, CDD, Compare to cluster

D0WGK0 Ketol-acid reductoisomerase (NADP(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.86
D0WGK0 ketol-acid reductoisomerase [NAD(P)+] (EC 1.1.1.383)
PFams: 2-Hacid_dh_C, IlvN, F420_oxidored, NAD_binding_2, IlvC
342 amino acids: PaperBLAST, CDD, Compare to cluster

D3PT81 ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: 2-Hacid_dh_C, IlvN, F420_oxidored, IlvC
339 amino acids: PaperBLAST, CDD, Compare to cluster

D6EC76 ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: 2-Hacid_dh_C, IlvN, F420_oxidored, NAD_binding_2, IlvC
332 amino acids: PaperBLAST, CDD, Compare to cluster

D6ERQ9 ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
Q9Z565 ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: 2-Hacid_dh_C, IlvN, F420_oxidored, NAD_binding_2, IlvC
332 amino acids: PaperBLAST, CDD, Compare to cluster

E0SRA9 Ketol-acid reductoisomerase (NAD(P)(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.383
E0SRA9 ketol-acid reductoisomerase (NAD+) (EC 1.1.1.382); ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: IlvN, F420_oxidored, IlvC
335 amino acids: PaperBLAST, CDD, Compare to cluster

P9WKJ7 Ketol-acid reductoisomerase (NADP(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.86
P9WKJ7 ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: 2-Hacid_dh_C, IlvN, NAD_binding_2, IlvC
337 amino acids: PaperBLAST, CDD, Compare to cluster

Q02138 Ketol-acid reductoisomerase (NADP(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.86
Q02138 ketol-acid reductoisomerase [NAD(P)+] (EC 1.1.1.383)
PFams: 2-Hacid_dh_C, AdoHcyase_NAD, IlvN, F420_oxidored, NAD_binding_2, IlvC
340 amino acids: PaperBLAST, CDD, Compare to cluster

Q59818 ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: 2-Hacid_dh_C, IlvN, F420_oxidored, NAD_binding_2, IlvC
333 amino acids: PaperBLAST, CDD, Compare to cluster

Q64BR7 Ketol-acid reductoisomerase (NAD(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.382
Q64BR7 ketol-acid reductoisomerase (NAD+) (EC 1.1.1.382); ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: AdoHcyase_NAD, IlvN, IlvC
332 amino acids: PaperBLAST, CDD, Compare to cluster

Q9FBT8 ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: 2-Hacid_dh_C, IlvN, F420_oxidored, NAD_binding_2, IlvC
332 amino acids: PaperBLAST, CDD, Compare to cluster

CH_123630 mitochondrial ketol-acid reductoisomerase (from HMM only)
PFams: IlvN, IlvC
400 amino acids: PaperBLAST, CDD, Compare to cluster

A4YI15 Ketol-acid reductoisomerase (NAD(P)(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.383
PFams: 2-Hacid_dh_C, AdoHcyase_NAD, IlvN, F420_oxidored, NAD_binding_2, IlvC
335 amino acids: PaperBLAST, CDD, Compare to cluster

A8ZTR0 Ketol-acid reductoisomerase (NAD(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; EC 1.1.1.382
PFams: IlvN, IlvC
352 amino acids: PaperBLAST, CDD, Compare to cluster

B4U6I9 Ketol-acid reductoisomerase (NAD(P)(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.383
PFams: AdoHcyase_NAD, IlvN, F420_oxidored, IlvC
333 amino acids: PaperBLAST, CDD, Compare to cluster

K4LVZ1 Ketol-acid reductoisomerase (NAD(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.382
PFams: 2-Hacid_dh_C, AdoHcyase_NAD, IlvN, F420_oxidored, NAD_binding_2, IlvC
332 amino acids: PaperBLAST, CDD, Compare to cluster

O28294 Ketol-acid reductoisomerase (NAD(P)(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.383
PFams: 2-Hacid_dh_C, AdoHcyase_NAD, IlvN, F420_oxidored, IlvC
332 amino acids: PaperBLAST, CDD, Compare to cluster

P06168 Ketol-acid reductoisomerase, mitochondrial; Acetohydroxy-acid reductoisomerase; Alpha-keto-beta-hydroxylacyl reductoisomerase; EC 1.1.1.86
PFams: IlvN, IlvC
395 amino acids: PaperBLAST, CDD, Compare to cluster

Q0AV19 Ketol-acid reductoisomerase (NAD(P)(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.383
PFams: 2-Hacid_dh_C, IlvN, F420_oxidored, NAD_binding_2, IlvC
337 amino acids: PaperBLAST, CDD, Compare to cluster

Q9HVA2 Ketol-acid reductoisomerase (NADP(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type I; EC 1.1.1.86
PFams: 2-Hacid_dh_C, IlvN, F420_oxidored, NAD_binding_2, IlvC
338 amino acids: PaperBLAST, CDD, Compare to cluster

MONOMER-18814 acetohydroxyacid isomeroreductase (EC 1.1.1.86)
PFams: 2-Hacid_dh_C, AdoHcyase_NAD, IlvN, F420_oxidored, NAD_binding_2, IlvC
338 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 491-492 amino acids (not heteromeric)

A0KS29 ketol-acid reductoisomerase [NAD(P)+] (EC 1.1.1.383)
PFams: IlvN, IlvC, IlvC
492 amino acids: PaperBLAST, CDD, Compare to cluster

A6TGG1 ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
PFams: IlvN, IlvC, IlvC
491 amino acids: PaperBLAST, CDD, Compare to cluster

KETOLREDUCTOISOM-MONOMER ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86; EC 1.1.1.169)
P05793 Ketol-acid reductoisomerase (NADP(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 2; Ketol-acid reductoisomerase type II; EC 1.1.1.86
P05793 ketol-acid reductoisomerase [NAD(P)+] (EC 1.1.1.383); ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86)
CH_003903 ketol-acid reductoisomerase; EC 1.1.1.86
PFams: IlvN, IlvC, IlvC
491 amino acids: PaperBLAST, CDD, Compare to cluster

P05989 Ketol-acid reductoisomerase (NADP(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 2; Ketol-acid reductoisomerase type II; EC 1.1.1.86
PFams: IlvN, IlvC, IlvC
491 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 578-595 amino acids (not heteromeric)

Q01292 Ketol-acid reductoisomerase, chloroplastic; Acetohydroxy-acid reductoisomerase; Alpha-keto-beta-hydroxylacyl reductoisomerase; EC 1.1.1.86
PFams: IlvN, IlvC, IlvC
595 amino acids: PaperBLAST, CDD, Compare to cluster

Q65XK0 Ketol-acid reductoisomerase, chloroplastic; Acetohydroxy-acid reductoisomerase; Alpha-keto-beta-hydroxylacyl reductoisomerase; Protein KARI; EC 1.1.1.86
PFams: IlvN, IlvC, IlvC
578 amino acids: PaperBLAST, CDD, Compare to cluster