GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for ilvI (acetolactate/acetohydroxybutanoate synthase catalytic subunit) in L-leucine biosynthesis

Or see other characterized proteins similar to ilvI

Or see all steps for L-leucine biosynthesis

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Definition of ilvI

Fetched 7 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 5 of these sequences

Found 1 clusters of similar sequences. Another 2 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 548-618 amino acids (4/5 heteromeric)

The first sequence in each cluster is the seed.

b0077 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655
P00893 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli (strain K12)
P00893 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli
PFams: TPP_enzyme_N, TPP_enzyme_M, TPP_enzyme_C
Heteromeric, 574 amino acids: PaperBLAST, CDD, Compare to cluster

ILVB1_MYCTU / P9WG41 Acetolactate synthase large subunit IlvB1; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WG41 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Mycobacterium tuberculosis
PFams: TPP_enzyme_N, TPP_enzyme_M, TPP_enzyme_C
Heteromeric, 618 amino acids: PaperBLAST, CDD, Compare to cluster

ILVG_ECOLI / P0DP90 Acetolactate synthase isozyme 2 large subunit; AHAS-II; ALS-II; Acetohydroxy-acid synthase II large subunit; EC 2.2.1.6 from Escherichia coli (strain K12)
GB|CAA28573.1 acetolactate synthase isozyme 2 large subunit; EC 2.2.1.6 from Escherichia coli K12
PFams: TPP_enzyme_N, TPP_enzyme_M, TPP_enzyme_C
548 amino acids: PaperBLAST, CDD, Compare to cluster

O08353 acetohydroxy-acid synthase large subunit (EC 2.2.1.6) from Methanococcus aeolicus
PFams: TPP_enzyme_N, TPP_enzyme_M, TPP_enzyme_C
Heteromeric, 599 amino acids: PaperBLAST, CDD, Compare to cluster

Q0KCU4 acetohydroxyacid synthase subunit B (EC 2.2.1.6) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)
PFams: TPP_enzyme_N, TPP_enzyme_M, TPP_enzyme_C
Heteromeric, 585 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (2/2 heteromeric)

ILVB2_MYCTU / O06335 Putative acetolactate synthase large subunit IlvB2; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
O06335 acetolactate synthase (EC 2.2.1.6) from Mycobacterium tuberculosis
PFams: TPP_enzyme_N, TPP_enzyme_M, TPP_enzyme_C
Heteromeric, 552 amino acids: PaperBLAST, CDD

ILVG_MYCTU / P9WG39 Acetolactate synthase large subunit IlvG; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WG39 acetolactate synthase (EC 2.2.1.6) from Mycobacterium tuberculosis
PFams: TPP_enzyme_N, TPP_enzyme_M, TPP_enzyme_C
Heteromeric, 547 amino acids: PaperBLAST, CDD