GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for leuD (3-isopropylmalate dehydaratase, small subunit) in L-leucine biosynthesis

Or see other characterized proteins similar to leuD

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Definition of leuD

Fetched 13 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 13 of these sequences

Found 4 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 197-201 amino acids (heteromeric)

P65278 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33
P9WK95 3-isopropylmalate dehydratase (EC 4.2.1.33)
PFams: Aconitase_C
Heteromeric, 198 amino acids: PaperBLAST, CDD, Compare to cluster

P04787 3-isopropylmalate dehydratase small subunit 1; Alpha-IPM isomerase 1; IPMI 1; Isopropylmalate isomerase 1; EC 4.2.1.33
PFams: Aconitase_C
Heteromeric, 201 amino acids: PaperBLAST, CDD, Compare to cluster

Q8NQV7 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33
PFams: Aconitase_C
Heteromeric, 197 amino acids: PaperBLAST, CDD, Compare to cluster

LEUD-MONOMER 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33)
LEUD-MONOMER LeuD
PFams: Aconitase_C
Heteromeric, 201 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 251-256 amino acids (heteromeric)

Q9LYT7 3-isopropylmalate dehydratase small subunit 2; AtLEUD2; Isopropylmalate isomerase small subunit 1; EC 4.2.1.33
Q9LYT7 2-(omega-methylthio)alkylmalate dehydratase (subunit 1/2) (EC 4.2.1.170); 3-isopropylmalate dehydratase (EC 4.2.1.33)
PFams: Aconitase_C
Heteromeric, 253 amino acids: PaperBLAST, CDD, Compare to cluster

Q9ZW84 3-isopropylmalate dehydratase small subunit 1; AtLEUD1; Isopropylmalate isomerase small subunit 2; EC 4.2.1.33
Q9ZW84 3-isopropylmalate dehydratase (EC 4.2.1.33)
PFams: Aconitase_C
Heteromeric, 256 amino acids: PaperBLAST, CDD, Compare to cluster

Q9ZW85 3-isopropylmalate dehydratase small subunit 3; AtLEUD3; Isopropylmalate isomerase small subunit 3; EC 4.2.1.33
Q9ZW85 2-(omega-methylthio)alkylmalate dehydratase (subunit 1/2) (EC 4.2.1.170); 3-isopropylmalate dehydratase (EC 4.2.1.33)
PFams: Aconitase_C
Heteromeric, 251 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 163-170 amino acids (2/3 heteromeric)

Q58667 Methanogen homoaconitase small subunit; HACN; Homoaconitate hydratase; EC 4.2.1.114 (from HMM only)
PFams: Aconitase_2_N, Aconitase_C
Heteromeric, 170 amino acids: PaperBLAST, CDD, Compare to cluster

Q9ZND9 Homoaconitase small subunit; HACN; Homoaconitate hydratase; EC 4.2.1.36 (from HMM only)
PFams: Aconitase_C
Heteromeric, 163 amino acids: PaperBLAST, CDD, Compare to cluster

LEUD_DESVH 3-isopropylmalate dehydratase small subunit {ECO:0000255|HAMAP-Rule:MF_01032}; EC=4.2.1.33 {ECO:0000255|HAMAP-Rule:MF_01032}; Alpha-IPM isomerase {ECO:0000255|HAMAP-Rule:MF_01032}; Short=IPMI {ECO:0000255|HAMAP-Rule:MF_01032}; AltName: Full=Isopropylmalate isomerase {ECO:0000255|HAMAP-Rule:MF_01032}
167 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 811-843 amino acids (not heteromeric)

C9K7B9 Aconitase AMT8; AM-toxin biosynthesis protein 8; EC 4.2.1.- (from HMM only)
PFams: Aconitase, Aconitase, Aconitase_C
840 amino acids: PaperBLAST, CDD, Compare to cluster

C9K7I3 Aconitase AMT8-2; AM-toxin biosynthesis protein 8-2; EC 4.2.1.- (from HMM only)
PFams: Aconitase, Aconitase, Aconitase_C
843 amino acids: PaperBLAST, CDD, Compare to cluster

Q4WBR0 Putative aconitate hydratase; Aconitase 3; EC 4.2.1.- (from HMM only)
PFams: Aconitase, Aconitase_C
811 amino acids: PaperBLAST, CDD, Compare to cluster