GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for dapA (4-hydroxy-tetrahydrodipicolinate synthase) in L-lysine biosynthesis

Or see other characterized proteins similar to dapA

Or see all steps for L-lysine biosynthesis

Or cluster curated proteins matching a keyword

Definition of dapA

Fetched 23 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 23 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 289-365 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

CH_021853 dihydrodipicolinate synthase; EC 4.2.1.52 from Bacillus anthracis
PFams: DHDPS
292 amino acids: PaperBLAST, CDD, Compare to cluster

A5F699 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Vibrio cholerae
PFams: DHDPS
292 amino acids: PaperBLAST, CDD, Compare to cluster

A9CFV4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens
PFams: DHDPS
303 amino acids: PaperBLAST, CDD, Compare to cluster

O67216 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Aquifex aeolicus
PFams: DHDPS
294 amino acids: PaperBLAST, CDD, Compare to cluster

b2478 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli K-12 substr. MG1655
P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (strain K12)
DAPA_ECOLI / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Escherichia coli (strain K12)
P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli
PFams: DHDPS
292 amino acids: PaperBLAST, CDD, Compare to cluster

P19808 dihydropicolinate synthase subunit (EC 4.3.3.7) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)
P19808 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Corynebacterium glutamicum
PFams: DHDPS
301 amino acids: PaperBLAST, CDD, Compare to cluster

DAPA_STAAC / Q5HG25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Staphylococcus aureus (strain COL)
Q5HG25 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Staphylococcus aureus
PFams: DHDPS
295 amino acids: PaperBLAST, CDD, Compare to cluster

Q6G468 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bartonella henselae
PFams: DHDPS
294 amino acids: PaperBLAST, CDD, Compare to cluster

DAPA_STAAR / Q6GH13 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Staphylococcus aureus (strain MRSA252)
Q6GH13 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Staphylococcus aureus
PFams: DHDPS
295 amino acids: PaperBLAST, CDD, Compare to cluster

Q7CU96 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens
PFams: DHDPS
298 amino acids: PaperBLAST, CDD, Compare to cluster

Q7D3Z9 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens
PFams: DHDPS
297 amino acids: PaperBLAST, CDD, Compare to cluster

Q8RBI5 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Caldanaerobacter subterraneus subsp. tengcongensis
PFams: DHDPS
297 amino acids: PaperBLAST, CDD, Compare to cluster

DAPA_AGRFC / Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens
PFams: DHDPS
294 amino acids: PaperBLAST, CDD, Compare to cluster

Q9FVC8 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Arabidopsis thaliana
PFams: DHDPS
365 amino acids: PaperBLAST, CDD, Compare to cluster

DAPA_PSEAE / Q9I4W3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9I4W3 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Pseudomonas aeruginosa
PFams: DHDPS
292 amino acids: PaperBLAST, CDD, Compare to cluster

DAPA_MYCTU / P9WP25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: DHDPS
300 amino acids: PaperBLAST, CDD, Compare to cluster

DAPA_RHIML / Q07607 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; Protein MosA; EC 4.3.3.7 from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti)
Q07607 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Sinorhizobium meliloti
PFams: DHDPS
292 amino acids: PaperBLAST, CDD, Compare to cluster

DAPA_METJA / Q57695 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
PFams: DHDPS
289 amino acids: PaperBLAST, CDD, Compare to cluster

DAPA_NEIMB / Q9JZR4 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Neisseria meningitidis serogroup B (strain MC58)
Q9JZR4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Neisseria meningitidis
PFams: DHDPS
291 amino acids: PaperBLAST, CDD, Compare to cluster

DAPA_THEMA / Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
PFams: DHDPS
294 amino acids: PaperBLAST, CDD, Compare to cluster

Q04796 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bacillus subtilis (strain 168)
PFams: DHDPS
290 amino acids: PaperBLAST, CDD, Compare to cluster

Q65JG7 dihydrodipicolinate synthase subunit (EC 4.3.3.7) from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)
PFams: DHDPS
289 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

P24846 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Triticum aestivum
PFams: DHDPS
388 amino acids: PaperBLAST, CDD
(similar to BRENDA::Q9FVC8 from Cluster 1, but similarity to seed sequence is below thresholds)