GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for dapC (N-succinyldiaminopimelate aminotransferase) in L-lysine biosynthesis

Or see other characterized proteins similar to dapC

Or see all steps for L-lysine biosynthesis

Or cluster curated proteins matching a keyword

Definition of dapC

Fetched 26 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 24 of these sequences

Found 5 clusters of similar sequences. Another 2 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 361-430 amino acids (not heteromeric)

b0907 phosphoserine/phosphohydroxythreonine aminotransferase (EC 2.6.1.52; EC 2.6.1.17) from Escherichia coli K-12 substr. MG1655
P23721 phosphoserine/phosphohydroxythreonine aminotransferase (EC 2.6.1.52; EC 2.6.1.17) from Escherichia coli (strain K12)
SERC_ECOLI / P23721 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Escherichia coli (strain K12)
P23721 phosphoserine transaminase (EC 2.6.1.52) from Escherichia coli
CH_002572 phosphoserine aminotransferase; EC 2.6.1.52 from Escherichia coli K12
PFams: Aminotran_5
362 amino acids: PaperBLAST, CDD, Compare to cluster

Q2F5M8 phosphoserine transaminase (EC 2.6.1.52) from Bombyx mori
PFams: Aminotran_5
364 amino acids: PaperBLAST, CDD, Compare to cluster

Q96255 phosphoserine aminotransferase (EC 2.6.1.52) from Arabidopsis thaliana
SERB1_ARATH / Q96255 Phosphoserine aminotransferase 1, chloroplastic; AtPSAT1; Phosphohydroxythreonine aminotransferase; EC 2.6.1.52 from Arabidopsis thaliana (Mouse-ear cress)
Q96255 phosphoserine transaminase (EC 2.6.1.52) from Arabidopsis thaliana
PFams: Aminotran_5
430 amino acids: PaperBLAST, CDD, Compare to cluster

SERB2_ARATH / Q9SHP0 Phosphoserine aminotransferase 2, chloroplastic; AtPSAT2; EC 2.6.1.52 from Arabidopsis thaliana (Mouse-ear cress)
Q9SHP0 phosphoserine transaminase (EC 2.6.1.52) from Arabidopsis thaliana
PFams: Aminotran_5
422 amino acids: PaperBLAST, CDD, Compare to cluster

Q9Y617 Phosphoserine aminotransferase (EC 2.6.1.52) from Homo sapiens
SERC_HUMAN / Q9Y617 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Homo sapiens (Human)
Q9Y617 glycine transaminase (EC 2.6.1.4); phosphoserine transaminase (EC 2.6.1.52) from Homo sapiens
PFams: Aminotran_5
370 amino acids: PaperBLAST, CDD, Compare to cluster

V9NC98 phosphoserine transaminase (EC 2.6.1.52) from Acanthamoeba castellanii
PFams: Aminotran_5
394 amino acids: PaperBLAST, CDD, Compare to cluster

SERC_RABIT / P10658 Phosphoserine aminotransferase; PSAT; Endometrial progesterone-induced protein; EPIP; Phosphohydroxythreonine aminotransferase; EC 2.6.1.52 from Oryctolagus cuniculus (Rabbit)
PFams: Aminotran_5
370 amino acids: PaperBLAST, CDD, Compare to cluster

SERC_YEAST / P33330 Phosphoserine aminotransferase; PSAT; Phosphohydroxythreonine aminotransferase; Serine requiring protein 1; EC 2.6.1.52 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Aminotran_5
395 amino acids: PaperBLAST, CDD, Compare to cluster

SERC_SPIOL / P52877 Phosphoserine aminotransferase, chloroplastic; PSAT; Phosphohydroxythreonine aminotransferase; EC 2.6.1.52 from Spinacia oleracea (Spinach)
PFams: Aminotran_5
430 amino acids: PaperBLAST, CDD, Compare to cluster

SERC_NIACI / Q59196 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Niallia circulans (Bacillus circulans)
Q59196 phosphoserine transaminase (EC 2.6.1.52) from Niallia circulans
PFams: Aminotran_5
362 amino acids: PaperBLAST, CDD, Compare to cluster

SERC_ALKAL / Q9RME2 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Alkalihalobacillus alcalophilus (Bacillus alcalophilus)
Q9RME2 phosphoserine transaminase (EC 2.6.1.52) from Alkalihalobacillus alcalophilus
PFams: Aminotran_5
361 amino acids: PaperBLAST, CDD, Compare to cluster

SERC_DROME / Q9VAN0 Probable phosphoserine aminotransferase; PSAT; Phosphohydroxythreonine aminotransferase; EC 2.6.1.52 from Drosophila melanogaster (Fruit fly)
PFams: Aminotran_5
364 amino acids: PaperBLAST, CDD, Compare to cluster

A2FXW5 phosphoserine transaminase (EC 2.6.1.52) from Trichomonas vaginalis (strain ATCC PRA-98 / G3)
PFams: Aminotran_5
371 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 359-397 amino acids (not heteromeric)

Q82IK5 succinyldiaminopimelate transaminase (EC 2.6.1.17); glutamate-prephenate aminotransferase (EC 2.6.1.79) from Streptomyces avermitilis
PFams: Aminotran_1_2
364 amino acids: PaperBLAST, CDD, Compare to cluster

Q8NRE6 succinyldiaminopimelate transaminase (EC 2.6.1.17) from Corynebacterium glutamicum
PFams: Aminotran_1_2
367 amino acids: PaperBLAST, CDD, Compare to cluster

L8EVF8 4-dedimethylamino-4-oxo-anhydrotetracycline transaminase (from HMM only) from Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234)
OXYQ_STRRM / Q3S8P9 4-dedimethylamino-4-oxo-anhydrotetracycline transaminase OxyQ; PLP-dependent aminotransferase OxyQ; Reductive transaminase oxyQ; EC 2.6.1.- from Streptomyces rimosus
PFams: Aminotran_1_2
359 amino acids: PaperBLAST, CDD, Compare to cluster

Q9ZEX3 N-succinyldiaminopimelate-aminotransferase (EC 2.6.1.17) from Bordetella pertussis
Q9ZEX3 succinyldiaminopimelate transaminase (EC 2.6.1.17) from Bordetella pertussis
PFams: Aminotran_1_2
397 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 389-406 amino acids (not heteromeric)

b3359 N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase (EC 2.6.1.11; EC 2.6.1.17) from Escherichia coli K-12 substr. MG1655
P18335 N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase (EC 2.6.1.11; EC 2.6.1.17) from Escherichia coli (strain K12)
ARGD_ECOLI / P18335 Acetylornithine/succinyldiaminopimelate aminotransferase; ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 from Escherichia coli (strain K12)
PFams: Aminotran_3, Aminotran_1_2
406 amino acids: PaperBLAST, CDD, Compare to cluster

ARGD_SALTY / P40732 Acetylornithine/succinyldiaminopimelate aminotransferase; ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aminotran_3, Aminotran_1_2
405 amino acids: PaperBLAST, CDD, Compare to cluster

AZOBR_RS19025 acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] from Azospirillum brasilense Sp245
PFams: Aminotran_3
389 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 384-385 amino acids (not heteromeric)

P74281 serine—glyoxylate transaminase (EC 2.6.1.52) from Synechocystis sp. (strain PCC 6803 / Kazusa)
P74281 phosphoserine transaminase (EC 2.6.1.52) from Synechocystis sp.
PFams: Aminotran_5
384 amino acids: PaperBLAST, CDD, Compare to cluster

Q58369 phosphoserine aminotransferase monomer (EC 2.6.1.1; EC 2.6.1.52) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
PFams: Aminotran_5
385 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 5 370-370 amino acids (not heteromeric)

SERC_METBF / P52878 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Methanosarcina barkeri (strain Fusaro / DSM 804)
P52878 phosphoserine transaminase (EC 2.6.1.52) from Methanosarcina barkeri
370 amino acids: PaperBLAST, CDD, Compare to cluster

Q8TNI1 phosphoserine aminotransferase monomer (EC 2.6.1.52; EC 2.6.1.1) from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
370 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/2 heteromeric)

DAPC_MYCTU / P9WPZ5 Probable N-succinyldiaminopimelate aminotransferase DapC; DAP-AT; EC 2.6.1.17 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WPZ5 succinyldiaminopimelate transaminase (EC 2.6.1.17) from Mycobacterium tuberculosis
PFams: Aminotran_1_2, Aminotran_5
397 amino acids: PaperBLAST, CDD

SERC_MYCTU / P9WQ73 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WQ73 phosphoserine transaminase (EC 2.6.1.52) from Mycobacterium tuberculosis
PFams: Aminotran_5
376 amino acids: PaperBLAST, CDD