GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for hcs (homocitrate synthase) in L-lysine biosynthesis

Or see other characterized proteins similar to hcs

Or see all steps for L-lysine biosynthesis

Or cluster curated proteins matching a keyword

Definition of hcs

Fetched 10 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 9 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 376-464 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

M1U949 homocitrate synthase (EC 2.3.3.14)
PFams: HMGL-like
464 amino acids: PaperBLAST, CDD, Compare to cluster

C7C437 homocitrate synthase (EC 2.3.3.14)
PFams: HMGL-like
463 amino acids: PaperBLAST, CDD, Compare to cluster

YDL182W-MONOMER homocitrate synthase (EC 2.3.3.14)
P48570 Homocitrate synthase, cytosolic isozyme; EC 2.3.3.14
P48570 homocitrate synthase (EC 2.3.3.14)
PFams: HMGL-like
428 amino acids: PaperBLAST, CDD, Compare to cluster

P58637 homocitrate synthase (EC 2.3.3.14)
PFams: HMGL-like
376 amino acids: PaperBLAST, CDD, Compare to cluster

YDL131W-MONOMER homocitrate synthase (EC 2.3.3.14)
Q12122 Homocitrate synthase, mitochondrial; EC 2.3.3.14
Q12122 homocitrate synthase (EC 2.3.3.14)
PFams: HMGL-like
440 amino acids: PaperBLAST, CDD, Compare to cluster

CH_126139 homocitrate synthase (predicted); EC 2.3.3.14
PFams: HMGL-like
418 amino acids: PaperBLAST, CDD, Compare to cluster

P05342 Homocitrate synthase; EC 2.3.3.14
PFams: HMGL-like
385 amino acids: PaperBLAST, CDD, Compare to cluster

Q57926 Probable homocitrate synthase AksA; (R)-homo(2)citrate synthase; (R)-homo(3)citrate synthase; EC 2.3.3.14; EC 2.3.3.-
PFams: HMGL-like
406 amino acids: PaperBLAST, CDD, Compare to cluster

MONOMER-6722 homocitrate synthase (EC 2.3.3.14)
PFams: HMGL-like
376 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

D0VY45 homocitrate synthase (EC 2.3.3.14)
PFams: HMGL-like, LeuA_dimer
540 amino acids: PaperBLAST, CDD