Other Characterized Proteins Similar to lysT

GapMind for Amino acid biosynthesis

Other Characterized Proteins Similar to lysT

Finding the characterized proteins for lysT (homoaconitase large subunit) in L-lysine biosynthesis

Or see clustering for step lysT

Or see all steps for L-lysine biosynthesis

Or cluster curated proteins matching a keyword

Definition of lysT

Curated proteins matching homoaconitase large subunit
Ignore hits to items matching EC 4.2.1.114 when looking for 'other' hits
Ignore hits to items matching EC 4.2.1.36 when looking for 'other' hits
Comment: (2R)-homocitrate to (1R,2S)-homoisocitrate via cis-homoaconitate

Fetched 2 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 4 other characterized sequences. (Found 6 hits including self hits.)

Removing ignored items reduces this to 3 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for lysT.)

DVU2982 isopropylmalate/citramalate isomerase large subunit LeuC (EC 4.2.1.33; EC 4.2.1.35) from Desulfovibrio vulgaris Hildenborough JW710
PFams: Aconitase, Aconitase
Heteromeric, 419 amino acids: PaperBLAST, CDD, reanno::DvH:208495
44% identical to

Q58409 homoaconitase α subunit (EC 4.2.1.36) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
HACA_METJA / Q58409 Methanogen homoaconitase large subunit; HACN; Homoaconitate hydratase; EC 4.2.1.114 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Q58409 methanogen homoaconitase (EC 4.2.1.114) from Methanocaldococcus jannaschii
CH_091727 homoaconitase; EC 4.2.1.-; EC 4.2.1.36 from Methanocaldococcus jannaschii
PFams: Aconitase, Aconitase
Heteromeric, 420 amino acids: PaperBLAST, CDD

Q0QLE2 dimethylmaleate hydratase subunit A (EC 4.2.1.85) from Eubacterium barkeri
DMDA_EUBBA / Q0QLE2 2,3-dimethylmalate dehydratase large subunit; EC 4.2.1.85 from Eubacterium barkeri (Clostridium barkeri)
PFams: Aconitase
Heteromeric, 420 amino acids: PaperBLAST, CDD, SwissProt::Q0QLE2
43% identical to

B2J8P2 benzylmalate isomerase from Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
PFams: Aconitase_C, Aconitase, Aconitase
569 amino acids: PaperBLAST, CDD, metacyc::MONOMER-18024
41% identical to

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for lysT.)

P81291 isopropylmalate isomerase large subunit (EC 4.2.1.35) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
LEUC_METJA / P81291 Isopropylmalate/citramalate isomerase large subunit; (R)-2-methylmalate dehydratase; (R)-citramalate dehydratase; 3-isopropylmalate dehydratase; Alpha-isopropylmalate dehydratase; Citraconate hydratase; Isopropylmalate isomerase; IPMI; Maleate hydratase; Malease; EC 4.2.1.33; EC 4.2.1.35; EC 4.2.1.31 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
P81291 3-isopropylmalate dehydratase (EC 4.2.1.33); homoaconitate hydratase (EC 4.2.1.36) from Methanocaldococcus jannaschii
PFams: Aconitase, Aconitase
Heteromeric, 424 amino acids: PaperBLAST, CDD, BRENDA::P81291
49% identical to