Clusters of Characterized Proteins

GapMind for Amino acid biosynthesis

Clusters of Characterized Proteins

Clustering the characterized proteins for asd-S-transferase (sulfuration of L-aspartate semialdehyde, persulfide component) in L-methionine biosynthesis

Or see other characterized proteins similar to asd-S-transferase

Or see all steps for L-methionine biosynthesis

Or cluster curated proteins matching a keyword

Definition of asd-S-transferase

Curated sequence Q8TPT4: L-aspartate semialdehyde sulfurtransferase (EC 2.8.1.16). L-aspartate semialdehyde sulfurtransferase; EC 2.8.1.16. L-aspartate semialdehyde sulfurtransferase (EC 2.8.1.16)
Curated sequence 8500721: Homocysteine formation from aspartate semialdehyde (DUF39 component)
Curated sequence Q57564: L-aspartate semialdehyde sulfurtransferase (EC 2.8.1.16). L-aspartate semialdehyde sulfurtransferase; EC 2.8.1.16
Comment: In the reductive sulfuration of aspartate semialdehyde, the sulfurtransferase component is MA1821 or DvMF_1464 (see PMID:25315403 and PMC5764234) or Q57564 (from SwissProt). Although this reaction has not been biochemically demonstrated, a distant homolog performs a similar reaction, converting sulfoacetaldehyde to coenzyme M (see MJ1681 and PMID:30932481). (This family was formerly DUF39.)

Fetched 3 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 3 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 390-509 amino acids (1/3 heteromeric)

The first sequence in each cluster is the seed.

ASST_METJA / Q57564 L-aspartate semialdehyde sulfurtransferase; EC 2.8.1.16 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Q57564 L-aspartate semialdehyde sulfurtransferase (EC 2.8.1.16) from Methanocaldococcus jannaschii
PFams: HcyBio, CBS, CBS
509 amino acids: PaperBLAST, CDD, Compare to cluster

Q8TPT4 L-aspartate semialdehyde sulfurtransferase (EC 2.8.1.16) from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
ASST_METAC / Q8TPT4 L-aspartate semialdehyde sulfurtransferase; EC 2.8.1.16 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Q8TPT4 L-aspartate semialdehyde sulfurtransferase (EC 2.8.1.16) from Methanosarcina acetivorans
PFams: HcyBio, CBS, CBS
500 amino acids: PaperBLAST, CDD, Compare to cluster

DvMF_1464 Homocysteine formation from aspartate semialdehyde (DUF39 component) from Desulfovibrio vulgaris Miyazaki F
PFams: HcyBio
Heteromeric, 390 amino acids: PaperBLAST, CDD, Compare to cluster