Other Characterized Proteins Similar to metC

GapMind for Amino acid biosynthesis

Other Characterized Proteins Similar to metC

Finding the characterized proteins for metC (cystathionine beta-lyase) in L-methionine biosynthesis

Or see clustering for step metC

Or see all steps for L-methionine biosynthesis

Or cluster curated proteins matching a keyword

Definition of metC

Curated proteins or TIGRFams with EC 4.4.1.13
Ignore hits to Q84UD0 when looking for 'other' hits (cysteine-S-conjugate beta-lyase (EC 4.4.1.13); L-cystine beta-lyase (EC 4.4.1.35))
Ignore hits to Q9EYM7 when looking for 'other' hits (cysteine-S-conjugate beta-lyase (EC 4.4.1.13))
Ignore hits to Q9SIV0 when looking for 'other' hits (S-alkyl-thiohydroximate lyase SUR1; Protein ABERRANT LATERAL ROOT FORMATION 1; Protein HOOKLESS 3; Protein ROOTY; Protein ROOTY 1; Protein SUPERROOT 1; EC 4.4.1.-. alkyl-thiohydroximate C-S lyase (EC 4.4.1.13))
Ignore hits to CH_088676 when looking for 'other' hits (cystathionine beta-lyase; EC 4.4.1.8)
Ignore hits to Q46061 when looking for 'other' hits (L-cysteine desulfidase (EC 4.4.1.28))
Curated sequence Q5H4T8: cystathionine gamma-lyase (EC 4.4.1.1)
Comment: BRENDA annotates Q84UD0 with this EC number but it may be a cystine lyase only (PMID:12525491). BRENDA annotates Q9EYM7 with this EC but it appears to be a cystathionine beta synthase (PMID:12101301). Q9SIV0 appears to be specific to glucosinolate biosynthesis. CH_088676 is annotated as this but with a different EC number, so it is ignored. Q4606 is annotated as cysteine desulfidase but is nearly identical to Q93QC6, which is a cystathionine beta-lyase, so it is ignored. XoMetC (Q5H4T8) is annotated as a gamma-lyase by BRENDA, but it also has beta-lyase activity (PMID:24531493).

Fetched 30 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 48 other characterized sequences. (Found 78 hits including self hits.)

Removing ignored items reduces this to 46 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for metC.)

Q58FK9 kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Rattus norvegicus
PFams: Aminotran_1_2
454 amino acids: PaperBLAST, CDD, BRENDA::Q58FK9
90% identical to

KAT3_MOUSE / Q71RI9 Kynurenine--oxoglutarate transaminase 3; Cysteine-S-conjugate beta-lyase 2; Kynurenine aminotransferase 3; Kynurenine aminotransferase III; KATIII; Kynurenine--glyoxylate transaminase; Kynurenine--oxoglutarate transaminase III; EC 2.6.1.7; EC 4.4.1.13; EC 2.6.1.63 from Mus musculus (Mouse)
Q71RI9 glutamine-pyruvate transaminase (EC 2.6.1.15); kynurenine-oxoglutarate transaminase (EC 2.6.1.7); cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Mus musculus
PFams: Aminotran_1_2
455 amino acids: PaperBLAST, CDD

Q8BTY1 kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Mus musculus
PFams: Aminotran_1_2
424 amino acids: PaperBLAST, CDD, BRENDA::Q8BTY1
88% identical to

KAT1_RAT / Q08415 Kynurenine--oxoglutarate transaminase 1; Kynurenine--oxoglutarate transaminase I; Cysteine-S-conjugate beta-lyase; Glutamine transaminase K; GTK; Glutamine--phenylpyruvate transaminase; Kynurenine aminotransferase 1; Kynurenine aminotransferase I; KATI; EC 2.6.1.7; EC 4.4.1.13; EC 2.6.1.64 from Rattus norvegicus (Rat)
Q08415 kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Rattus norvegicus
PFams: Aminotran_1_2
423 amino acids: PaperBLAST, CDD

CH_122245 cystathionine beta-lyase; EC 4.4.1.8 from Emericella nidulans
PFams: Cys_Met_Meta_PP, Aminotran_1_2
439 amino acids: PaperBLAST, CDD, CharProtDB::CH_122245
76% identical to

CBL_NEUCR / Q1K8G0 Cystathionine beta-lyase; Cysteine-S-conjugate beta-lyase; EC 4.4.1.13 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Q1K8G0 cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Neurospora crassa
PFams: Cys_Met_Meta_PP, Aminotran_1_2, DegT_DnrJ_EryC1, Aminotran_5
457 amino acids: PaperBLAST, CDD

METB_HELPX / Q1M0P5 Cystathionine gamma-synthase; CGS; O-succinylhomoserine (thiol)-lyase; EC 2.5.1.48 from Helicobacter pylori (Campylobacter pylori)
Q1M0P5 cystathionine gamma-synthase (EC 2.5.1.48) from Helicobacter pylori
PFams: Cys_Met_Meta_PP, Aminotran_1_2
380 amino acids: PaperBLAST, CDD, SwissProt::Q1M0P5
66% identical to

A2RM21 cystathionine gamma-lyase (EC 4.4.1.1); cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Lactococcus lactis
RF|YP_001033049.1 cystathionine beta-lyase; EC 4.4.1.8 from Lactococcus lactis subsp. cremoris MG1363
PFams: Cys_Met_Meta_PP, Aminotran_1_2, DegT_DnrJ_EryC1, Aminotran_5
380 amino acids: PaperBLAST, CDD

P56069 cystathionine gamma-lyase (EC 4.4.1.1) from Helicobacter pylori (strain ATCC 700392 / 26695)
PFams: Cys_Met_Meta_PP, Aminotran_1_2
380 amino acids: PaperBLAST, CDD, metacyc::HP_RS00540-MONOMER
65% identical to

MCCB_BACSU / O05394 Cystathionine gamma-lyase; Gamma-cystathionase; Homocysteine gamma-lyase; EC 4.4.1.1; EC 4.4.1.2 from Bacillus subtilis (strain 168)
O05394 cystathionine beta-synthase (O-acetyl-L-serine) (EC 2.5.1.134) from Bacillus subtilis
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
379 amino acids: PaperBLAST, CDD, BRENDA::O05394
63% identical to

METB_MYCTU / P9WGB7 Cystathionine gamma-synthase; CGS; O-succinylhomoserine (thiol)-lyase; EC 2.5.1.48 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: Cys_Met_Meta_PP, Met_gamma_lyase, DegT_DnrJ_EryC1, Aminotran_1_2
388 amino acids: PaperBLAST, CDD, SwissProt::P9WGB7
56% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

CGL_DICDI / Q55DV9 Cystathionine gamma-lyase; CGL; CSE; Cysteine desulfhydrase; Cysteine-protein sulfhydrase; Gamma-cystathionase; Homocysteine desulfhydrase; EC 4.4.1.1; EC 4.4.1.2 from Dictyostelium discoideum (Social amoeba)
PFams: Cys_Met_Meta_PP, Aminotran_1_2
387 amino acids: PaperBLAST, CDD, SwissProt::Q55DV9
53% identical to

A0PKT3 cystathionine gamma-synthase (EC 2.5.1.48) from Mycobacterium ulcerans
PFams: Cys_Met_Meta_PP, Met_gamma_lyase, DegT_DnrJ_EryC1, Aminotran_5
388 amino acids: PaperBLAST, CDD, BRENDA::A0PKT3
54% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

CGL_MOUSE / Q8VCN5 Cystathionine gamma-lyase; CGL; CSE; Cysteine desulfhydrase; Cysteine-protein sulfhydrase; Gamma-cystathionase; Homocysteine desulfhydrase; EC 4.4.1.1; EC 4.4.1.2 from Mus musculus (Mouse)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, DegT_DnrJ_EryC1
398 amino acids: PaperBLAST, CDD, SwissProt::Q8VCN5
55% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

P32929 cystathionine γ-lyase monomer (EC 4.4.1.1; EC 4.4.1.2; EC 4.2.1.22) from Homo sapiens
CGL_HUMAN / P32929 Cystathionine gamma-lyase; CGL; CSE; Cysteine desulfhydrase; Cysteine-protein sulfhydrase; Gamma-cystathionase; Homocysteine desulfhydrase; EC 4.4.1.1; EC 4.4.1.2 from Homo sapiens (Human)
P32929 cystathionine gamma-lyase (EC 4.4.1.1) from Homo sapiens
PFams: Cys_Met_Meta_PP, Aminotran_1_2, DegT_DnrJ_EryC1, Aminotran_5
405 amino acids: PaperBLAST, CDD, BRENDA::P32929
54% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

P18757 cystathionine γ-lyase subunit (EC 4.4.1.1) from Rattus norvegicus
CGL_RAT / P18757 Cystathionine gamma-lyase; CGL; CSE; Cysteine desulfhydrase; Cysteine-protein sulfhydrase; Gamma-cystathionase; Homocysteine desulfhydrase; Probasin-related antigen; PRB-RA; EC 4.4.1.1; EC 4.4.1.2 from Rattus norvegicus (Rat)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
398 amino acids: PaperBLAST, CDD, SwissProt::P18757
54% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

KAT_AEDAE / Q17CS8 Kynurenine aminotransferase; AeKAT; EC 2.6.1.-; EC 2.6.1.63; EC 2.6.1.7 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
PFams: Aminotran_1_2
477 amino acids: PaperBLAST, CDD, SwissProt::Q17CS8
52% identical to

Q6YP21 Kynurenine--oxoglutarate transaminase 3 (EC 2.6.1.7; EC 4.4.1.13) from Homo sapiens
Q6YP21 kynurenine-oxoglutarate transaminase (EC 2.6.1.7); cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Homo sapiens
PFams: Aminotran_1_2
454 amino acids: PaperBLAST, CDD

B1B6U5 kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Haemaphysalis longicornis
GI|170172430 kynurenine aminotransferase; EC 2.6.1.7 from Haemaphysalis longicornis
PFams: Aminotran_1_2
415 amino acids: PaperBLAST, CDD, CharProtDB::CH_090817
51% identical to

Q16773 kynurenine aminotransferase I subunit (EC 2.6.1.117; EC 2.6.1.7; EC 4.4.1.13; EC 2.6.1.64) from Homo sapiens
KAT1_HUMAN / Q16773 Kynurenine--oxoglutarate transaminase 1; Cysteine-S-conjugate beta-lyase; Glutamine transaminase K; GTK; Glutamine--phenylpyruvate transaminase; Kynurenine aminotransferase 1; Kynurenine aminotransferase I; KATI; Kynurenine--oxoglutarate transaminase I; EC 2.6.1.7; EC 4.4.1.13; EC 2.6.1.64 from Homo sapiens (Human)
Q16773 kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Homo sapiens
PFams: Aminotran_1_2
422 amino acids: PaperBLAST, CDD

CH_124009 cystathionine-gamma-lyase [Acremonium chrysogenum] from Magnaporthe grisea 70-15
PFams: Cys_Met_Meta_PP, Aminotran_1_2
426 amino acids: PaperBLAST, CDD, CharProtDB::CH_124009
52% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

U6BYK3 mimosinase (EC 4.3.3.8) from Mimosa pudica
U6BYK3 mimosinase (EC 3.5.1.61) from Mimosa pudica
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Aminotran_5
442 amino acids: PaperBLAST, CDD, metacyc::MONOMER-124312
54% identical to

A0A0M3VI47 cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Mimosa pudica
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Aminotran_5
457 amino acids: PaperBLAST, CDD

MEGL_FUSNP / Q8L0X4 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-methionine-alpha-deamino-gamma-mercaptomethane-lyase; METase; EC 4.4.1.11; EC 4.4.1.2 from Fusobacterium nucleatum subsp. polymorphum (Fusobacterium polymorphum)
PFams: Cys_Met_Meta_PP, Met_gamma_lyase, Aminotran_1_2, Aminotran_5
395 amino acids: PaperBLAST, CDD, SwissProt::Q8L0X4
50% identical to

B2LXT6 cystathionine gamma-lyase (EC 4.4.1.1) from Aspergillus nidulans
CH_122519 cystathionine gamma-lyase; EC 4.4.1.1 from Emericella nidulans
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2
419 amino acids: PaperBLAST, CDD, CharProtDB::CH_122519
49% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

MEGL_FUSNN / Q8RDT4 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-cysteine desulfidase; EC 4.4.1.11; EC 4.4.1.2; EC 4.4.1.28 from Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)
Q8RDT4 methionine gamma-lyase (EC 4.4.1.11) from Fusobacterium nucleatum subsp. nucleatum
PFams: Cys_Met_Meta_PP, Met_gamma_lyase, Aminotran_1_2, Aminotran_5
395 amino acids: PaperBLAST, CDD, BRENDA::Q8RDT4
49% identical to

Q4WCI1 cystathionine gamma-lyase (EC 4.4.1.1) from Aspergillus fumigatus
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2
412 amino acids: PaperBLAST, CDD, BRENDA::Q4WCI1
49% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

H7C6A2 cystathionine gamma-synthase (EC 2.5.1.48) from Corynebacterium glutamicum
PFams: Cys_Met_Meta_PP, Aminotran_1_2, DegT_DnrJ_EryC1
386 amino acids: PaperBLAST, CDD, BRENDA::H7C6A2
49% identical to

A8CEI3 mimosinase (EC 3.5.1.61) from Leucaena leucocephala
PFams: Cys_Met_Meta_PP, Met_gamma_lyase, Aminotran_5, Aminotran_1_2
443 amino acids: PaperBLAST, CDD, BRENDA::A8CEI3
49% identical to

A0A0M3VI47 cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Mimosa pudica
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Aminotran_5
457 amino acids: PaperBLAST, CDD

Q96VU7 cystathionine gamma-lyase (EC 4.4.1.1) from Neurospora crassa
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Aminotran_5
417 amino acids: PaperBLAST, CDD, BRENDA::Q96VU7
50% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

A0A1L7H888 methionine gamma-lyase (EC 4.4.1.11) from Clostridium tetani
PFams: Cys_Met_Meta_PP, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_1_2, Met_gamma_lyase, Aminotran_5
398 amino acids: PaperBLAST, CDD, BRENDA::A0A1L7H888
48% identical to

P31373 Cys3 (EC 4.4.1.1) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYS3_YEAST / P31373 Cystathionine gamma-lyase; gamma-CTLase; Gamma-cystathionase; Sulfur transfer protein 1; EC 4.4.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P31373 cystathionine gamma-lyase (EC 4.4.1.1) from Saccharomyces cerevisiae
PFams: Cys_Met_Meta_PP
394 amino acids: PaperBLAST, CDD, BRENDA::P31373
48% identical to

METI_BACSU / O31631 Cystathionine gamma-synthase/O-acetylhomoserine (thiol)-lyase; CGS/OAH thiolyase; O-acetylhomoserine sulfhydrylase; OAH sulfhydrylase; EC 2.5.1.- from Bacillus subtilis (strain 168)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2
373 amino acids: PaperBLAST, CDD, SwissProt::O31631
47% identical to

O15565 methionine gamma-lyase (EC 4.4.1.11) from Trichomonas vaginalis
PFams: Cys_Met_Meta_PP, Met_gamma_lyase, Aminotran_1_2, Aminotran_5
398 amino acids: PaperBLAST, CDD, BRENDA::O15565
46% identical to

J7TA22 methionine gamma-lyase (EC 4.4.1.11) from Clostridium sporogenes
PFams: Cys_Met_Meta_PP, Met_gamma_lyase, Aminotran_1_2, Aminotran_5
400 amino acids: PaperBLAST, CDD, BRENDA::J7TA22
46% identical to

Q84AR1 methionine gamma-lyase (EC 4.4.1.11); alliin lyase (EC 4.4.1.4) from Citrobacter freundii
PFams: Cys_Met_Meta_PP, Met_gamma_lyase, Aminotran_1_2, Beta_elim_lyase, Aminotran_5
398 amino acids: PaperBLAST, CDD, BRENDA::Q84AR1
48% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

A0A0J6G7P5 methionine γ-lyase (EC 4.4.1.11) from Pseudomonas deceptionensis
MEGL_PSEDM / A0A0J6G7P5 L-methionine gamma-lyase; MGL; EC 4.4.1.11 from Pseudomonas deceptionensis
PFams: Cys_Met_Meta_PP, Met_gamma_lyase
399 amino acids: PaperBLAST, CDD, SwissProt::A0A0J6G7P5
45% identical to

P13254 MdeA from Pseudomonas putida
MEGL_PSEPU / P13254 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-methioninase; EC 4.4.1.11; EC 4.4.1.2 from Pseudomonas putida (Arthrobacter siderocapsulatus)
PFams: Cys_Met_Meta_PP, Beta_elim_lyase, Met_gamma_lyase, Aminotran_1_2, Aminotran_5
398 amino acids: PaperBLAST, CDD, SwissProt::P13254
46% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

Q5MQ31 methionine gamma-lyase (EC 4.4.1.11) from Brevibacterium linens
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
425 amino acids: PaperBLAST, CDD, BRENDA::Q5MQ31
46% identical to

METC_COXBU / Q83A83 Cystathionine beta-lyase; CBL; Beta-cystathionase; Cysteine lyase; Cysteine-S-conjugate beta-lyase; EC 4.4.1.13 from Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
PFams: Cys_Met_Meta_PP, Aminotran_1_2
387 amino acids: PaperBLAST, CDD

O15564 methionine gamma-lyase (EC 4.4.1.11) from Trichomonas vaginalis
PFams: Cys_Met_Meta_PP, Met_gamma_lyase, Aminotran_1_2, Aminotran_5
396 amino acids: PaperBLAST, CDD, BRENDA::O15564
45% identical to

SO1812 Methionine gamma-lyase (EC 4.4.1.11) from Shewanella oneidensis MR-1
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2
397 amino acids: PaperBLAST, CDD, reanno::MR1:200974
45% identical to

b3939 O-succinylhomoserine(thiol)-lyase / O-succinylhomoserine lyase (EC 2.5.1.48) from Escherichia coli K-12 substr. MG1655
P00935 O-succinylhomoserine(thiol)-lyase / O-succinylhomoserine lyase (EC 2.5.1.48) from Escherichia coli (strain K12)
METB_ECOLI / P00935 Cystathionine gamma-synthase; CGS; O-succinylhomoserine (thiol)-lyase; EC 2.5.1.48 from Escherichia coli (strain K12)
PFams: Cys_Met_Meta_PP, Aminotran_1_2
386 amino acids: PaperBLAST, CDD, SwissProt::P00935
45% identical to

MEGL_TREDE / Q73KL7 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-methionine-alpha-deamino-gamma-mercaptomethane-lyase; METase; EC 4.4.1.11; EC 4.4.1.2 from Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
Q73KL7 methionine gamma-lyase (EC 4.4.1.11) from Treponema denticola
PFams: Cys_Met_Meta_PP, Met_gamma_lyase
401 amino acids: PaperBLAST, CDD, BRENDA::Q73KL7
44% identical to

C3VMV9 methionine gamma-lyase (EC 4.4.1.11) from Porphyromonas gingivalis
PFams: Cys_Met_Meta_PP, Met_gamma_lyase, Aminotran_1_2, Aminotran_5
393 amino acids: PaperBLAST, CDD, BRENDA::C3VMV9
45% identical to

B3TNN8 cystathionine gamma-lyase (subunit 2/2) (EC 4.4.1.1); cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Lacticaseibacillus casei
PFams: Cys_Met_Meta_PP, Aminotran_1_2, DegT_DnrJ_EryC1, Aminotran_5
Heteromeric, 394 amino acids: PaperBLAST, CDD

MEGL_PORGI / Q7MX71 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-methionine-alpha-deamino-gamma-mercaptomethane-lyase; METase; EC 4.4.1.11; EC 4.4.1.2 from Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
Q7MX71 methionine gamma-lyase (EC 4.4.1.11) from Porphyromonas gingivalis
PFams: Cys_Met_Meta_PP, Met_gamma_lyase, Aminotran_1_2, Aminotran_5
399 amino acids: PaperBLAST, CDD, BRENDA::Q7MX71
45% identical to

Q8KNG3 methionine gamma-lyase (EC 4.4.1.11) from Micromonospora echinospora
PFams: Cys_Met_Meta_PP, Aminotran_1_2
381 amino acids: PaperBLAST, CDD, BRENDA::Q8KNG3
45% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

P55218 O-succinyl-L-homoserine sulfhydrylase (EC 2.5.1.48) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
METZ_PSEAE / P55218 O-succinylhomoserine sulfhydrylase; OSH sulfhydrylase; OSHS sulfhydrylase; EC 2.5.1.- from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Aminotran_5, DegT_DnrJ_EryC1
403 amino acids: PaperBLAST, CDD, SwissProt::P55218
43% identical to

Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae
PFams: Cys_Met_Meta_PP
397 amino acids: PaperBLAST, CDD

Q86D27 methionine gamma-lyase (EC 4.4.1.11) from Entamoeba histolytica
PFams: Cys_Met_Meta_PP, Aminotran_1_2
392 amino acids: PaperBLAST, CDD, BRENDA::Q86D27
41% identical to

P55217 cystathionine γ-synthase (EC 2.5.1.48) from Arabidopsis thaliana
CGS1_ARATH / P55217 Cystathionine gamma-synthase 1, chloroplastic; AtCGS1; METHIONINE OVERACCUMULATION 1; O-succinylhomoserine (thiol)-lyase; EC 2.5.1.48 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Cys_Met_Meta_PP
563 amino acids: PaperBLAST, CDD, SwissProt::P55217
41% identical to

Q86D28 methionine gamma-lyase (EC 4.4.1.11) from Entamoeba histolytica
PFams: Cys_Met_Meta_PP, Aminotran_1_2
389 amino acids: PaperBLAST, CDD, BRENDA::Q86D28
41% identical to

B6K8Y1 cystathionine gamma-lyase (EC 4.4.1.1) from Toxoplasma gondii
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
417 amino acids: PaperBLAST, CDD, BRENDA::B6K8Y1
42% identical to

E9AFE7 cystathionine gamma-lyase (EC 4.4.1.1) from Leishmania major
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1
409 amino acids: PaperBLAST, CDD, BRENDA::E9AFE7
40% identical to

L0EKR2 cystathionine gamma-synthase (EC 2.5.1.48) from Lens culinaris
PFams: Cys_Met_Meta_PP, Aminotran_1_2
535 amino acids: PaperBLAST, CDD, BRENDA::L0EKR2
40% identical to

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for metC.)

GB|AAF14695.1 cystathionine beta-lyase; EC 4.4.1.8 from Austrochilidae
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Aminotran_5
380 amino acids: PaperBLAST, CDD, CharProtDB::CH_088676
94% identical to

Q46061 L-cysteine desulfidase (EC 4.4.1.28) from Corynebacterium glutamicum
PFams: Aminotran_1_2
325 amino acids: PaperBLAST, CDD, BRENDA::Q46061
99% identical to

CBL_CORGT / Q93QC6 Cystathionine beta-lyase; CBL; Beta-cystathionase; Cysteine lyase; Cysteine-S-conjugate beta-lyase; EC 4.4.1.13 from Corynebacterium glutamicum (Brevibacterium saccharolyticum)
PFams: Aminotran_1_2
368 amino acids: PaperBLAST, CDD