GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for metE (vitamin B12-independent methionine synthase) in L-methionine biosynthesis

Or see other characterized proteins similar to metE

Or see all steps for L-methionine biosynthesis

Or cluster curated proteins matching a keyword

Definition of metE

Fetched 17 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 17 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 734-812 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

A0A077D1A3 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (EC 2.1.1.14) from Fragilariopsis cylindrus
PFams: Meth_synt_1, Meth_synt_2, Meth_synt_2
765 amino acids: PaperBLAST, CDD, Compare to cluster

A0A1B2JIW1 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (EC 2.1.1.14) from Komagataella pastoris
PFams: Meth_synt_1, Meth_synt_2
768 amino acids: PaperBLAST, CDD, Compare to cluster

METE1_ARATH / O50008 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1; Cobalamin-independent methionine synthase 1; AtMS1; Vitamin-B12-independent methionine synthase 1; EC 2.1.1.14 from Arabidopsis thaliana (Mouse-ear cress)
O50008 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (EC 2.1.1.14) from Arabidopsis thaliana
PFams: Meth_synt_1, Meth_synt_2
765 amino acids: PaperBLAST, CDD, Compare to cluster

P05694 cobalamin-independent methionine synthase (EC 2.1.1.14) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
METE_YEAST / P05694 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Cobalamin-independent methionine synthase; Delta-P8 protein; Methionine synthase, vitamin-B12 independent isozyme; EC 2.1.1.14 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P05694 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (EC 2.1.1.14) from Saccharomyces cerevisiae
PFams: Meth_synt_1, Meth_synt_2
767 amino acids: PaperBLAST, CDD, Compare to cluster

b3829 cobalamin-independent homocysteine transmethylase (EC 2.1.1.14) from Escherichia coli K-12 substr. MG1655
P25665 cobalamin-independent homocysteine transmethylase (EC 2.1.1.14) from Escherichia coli (strain K12)
P25665 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (EC 2.1.1.14) from Escherichia coli
CH_003938 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; EC 2.1.1.14 from Escherichia coli K12
PFams: Meth_synt_1, Meth_synt_2, Meth_synt_2
753 amino acids: PaperBLAST, CDD, Compare to cluster

METE_CANAL / P82610 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Cobalamin-independent methionine synthase; Methionine synthase, vitamin-B12 independent isozyme; EC 2.1.1.14 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
P82610 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (EC 2.1.1.14) from Candida albicans
CH_122913 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; EC 2.1.1.14 from Candida albicans
PFams: Meth_synt_1, Meth_synt_2
767 amino acids: PaperBLAST, CDD, Compare to cluster

Q6GYJ7 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (EC 2.1.1.14) from Komagataella pastoris
PFams: Meth_synt_1, Meth_synt_2
768 amino acids: PaperBLAST, CDD, Compare to cluster

Q8X1E4 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (EC 2.1.1.14) from Neurospora crassa
PFams: Meth_synt_1, Meth_synt_2
769 amino acids: PaperBLAST, CDD, Compare to cluster

METE_THEMA / Q9X112 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Cobalamin-independent methionine synthase; Methionine synthase, vitamin-B12 independent isozyme; EC 2.1.1.14 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Q9X112 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (EC 2.1.1.14) from Thermotoga maritima
PFams: Meth_synt_1, Meth_synt_2, Meth_synt_1
734 amino acids: PaperBLAST, CDD, Compare to cluster

CH_122650 cobalamin-independent methionine synthase; EC 2.1.1.14 from Emericella nidulans
PFams: Meth_synt_1, Meth_synt_2
774 amino acids: PaperBLAST, CDD, Compare to cluster

METE_SCHPO / Q9UT19 Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Cobalamin-independent methionine synthase; Methionine synthase, vitamin-B12 independent isozyme; EC 2.1.1.14 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
RF|NP_593352.1 homocysteine methyltransferase Met26; EC 2.1.1.14 from Schizosaccharomyces pombe
PFams: Meth_synt_1, Meth_synt_2
764 amino acids: PaperBLAST, CDD, Compare to cluster

METE_KALTU / C1KEU0 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Cobalamin-independent methionine synthase; Pollen allergen Sal k 3; SkMetE; Vitamin-B12-independent methionine synthase; Allergen Sal k 3.0101; EC 2.1.1.14 from Kali turgidum (Prickly saltwort) (Salsola kali)
PFams: Meth_synt_1, Meth_synt_2
757 amino acids: PaperBLAST, CDD, Compare to cluster

METE3_ARATH / Q0WNZ5 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 3, chloroplastic; Cobalamin-independent methionine synthase 3; AtMS3; EC 2.1.1.14 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Meth_synt_1, Meth_synt_2
812 amino acids: PaperBLAST, CDD, Compare to cluster

METE_STRMU / Q8CWX6 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Cobalamin-independent methionine synthase; Methionine synthase, vitamin-B12 independent isozyme; EC 2.1.1.14 from Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Q8CWX6 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (EC 2.1.1.14) from Streptococcus mutans
PFams: Meth_synt_1, Meth_synt_2, Meth_synt_2
745 amino acids: PaperBLAST, CDD, Compare to cluster

Q9SRV5 cobalamin-independent methionine synthase MS2 (EC 2.1.1.14) from Arabidopsis thaliana
METE2_ARATH / Q9SRV5 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 2; Cobalamin-independent methionine synthase 2; AtMS2; EC 2.1.1.14 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Meth_synt_1, Meth_synt_2
765 amino acids: PaperBLAST, CDD, Compare to cluster

Q8NRB3 cobalamin-independent methionine synthase (EC 2.1.1.14) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: Meth_synt_1, Meth_synt_2
745 amino acids: PaperBLAST, CDD, Compare to cluster

P80877 cobalamin-independent methionine synthase (EC 2.1.1.14) from Bacillus subtilis (strain 168)
PFams: Meth_synt_1, Meth_synt_2, Meth_synt_2, Meth_synt_1
762 amino acids: PaperBLAST, CDD, Compare to cluster