Clusters of Characterized Proteins

Clustering the characterized proteins for metY (O-acetylhomoserine sulfhydrylase) in L-methionine biosynthesis

Or see other characterized proteins similar to metY

Or see all steps for L-methionine biosynthesis

Or cluster curated proteins matching a keyword

Definition of metY

• Curated proteins or TIGRFams with EC 2.5.1.49
• Curated sequence O31631: Cystathionine gamma-synthase/O-acetylhomoserine (thiol)-lyase; CGS/OAH thiolyase; O-acetylhomoserine sulfhydrylase; OAH sulfhydrylase; EC 2.5.1.-
• Ignore hits to items matching O-succinylhomoserine sulfhydrylase when looking for 'other' hits
• Comment: METI_BACSU (O31631) has activity as OAS but is given a more vague EC number.

Fetched 12 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 12 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 373-449 amino acids (not heteromeric)

L7N4M1 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP
449 amino acids: PaperBLAST, CDD, Compare to cluster

P94890 O-acetyl-L-homoserine sulfhydrylase; OAH-sulfhydrylase; EC 2.5.1.-
P94890 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49)
MONOMER-9366 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1
442 amino acids: PaperBLAST, CDD, Compare to cluster

Q5SJ58 O-acetyl-L-homoserine sulfhydrylase 2; OAH-sulfhydrylase 2; EC 2.5.1.-
Q76K51 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2
412 amino acids: PaperBLAST, CDD, Compare to cluster

Q7M844 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Aminotran_5
422 amino acids: PaperBLAST, CDD, Compare to cluster

Q5SK88 O-acetyl-L-homoserine sulfhydrylase 1; OAH-sulfhydrylase 1; EC 2.5.1.-
Q93I77 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2
421 amino acids: PaperBLAST, CDD, Compare to cluster

P50125 Homocysteine synthase; O-acetylhomoserine sulfhydrylase; OAH SHL; OAH sulfhydrylase; EC 2.5.1.49
CH_122447 O-acetylhomoserine (thiol)-lyase; EC 2.5.1.49
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Beta_elim_lyase, Aminotran_1_2, Aminotran_5
437 amino acids: PaperBLAST, CDD, Compare to cluster

O13326 Homocysteine synthase; O-acetylhomoserine sulfhydrylase; OAH SHL; OAH sulfhydrylase; EC 2.5.1.49
CH_124469 homocysteine synthase Met17; EC 2.5.1.49
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
429 amino acids: PaperBLAST, CDD, Compare to cluster

O31631 Cystathionine gamma-synthase/O-acetylhomoserine (thiol)-lyase; CGS/OAH thiolyase; O-acetylhomoserine sulfhydrylase; OAH sulfhydrylase; EC 2.5.1.-
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
373 amino acids: PaperBLAST, CDD, Compare to cluster

P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49
YLR303W-MONOMER Met17 (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD, Compare to cluster

Q79VI4 O-acetyl-L-homoserine sulfhydrylase; OAH-sulfhydrylase; EC 2.5.1.49
G18NG-10215-MONOMER O-acetylhomoserine sulfhydrylase (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1
437 amino acids: PaperBLAST, CDD, Compare to cluster

MONOMER-17873 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1
438 amino acids: PaperBLAST, CDD, Compare to cluster

Korea:Ga0059261_3194 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_5, Aminotran_1_2
402 amino acids: PaperBLAST, CDD, Compare to cluster