GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for cmutase (chorismate mutase) in L-phenylalanine biosynthesis

Or see other characterized proteins similar to cmutase

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Definition of cmutase

Fetched 49 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 41 of these sequences

Found 10 clusters of similar sequences. Another 8 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 253-340 amino acids (not heteromeric)

A0A2K1JMA3 chorismate mutase (EC 5.4.99.5) from Physcomitrium patens
297 amino acids: PaperBLAST, CDD, Compare to cluster

A9S498 chorismate mutase (EC 5.4.99.5) from Physcomitrium patens
316 amino acids: PaperBLAST, CDD, Compare to cluster

D8R1Y1 chorismate mutase (EC 5.4.99.5) from Selaginella moellendorffii
267 amino acids: PaperBLAST, CDD, Compare to cluster

P42738 chorismate mutase (EC 5.4.99.5) from Arabidopsis thaliana
CM1_ARATH / P42738 Chorismate mutase 1, chloroplastic; AtCM1; CM-1; EC 5.4.99.5 from Arabidopsis thaliana (Mouse-ear cress)
P42738 chorismate mutase (EC 5.4.99.5) from Arabidopsis thaliana
340 amino acids: PaperBLAST, CDD, Compare to cluster

Q9C544 chorismate mutase (EC 5.4.99.5) from Arabidopsis thaliana
CM3_ARATH / Q9C544 Chorismate mutase 3, chloroplastic; AtCM3; CM-3; EC 5.4.99.5 from Arabidopsis thaliana (Mouse-ear cress)
Q9C544 chorismate mutase (EC 5.4.99.5) from Arabidopsis thaliana
316 amino acids: PaperBLAST, CDD, Compare to cluster

Q9S7H4 chorismate mutase (EC 5.4.99.5) from Arabidopsis thaliana
CM2_ARATH / Q9S7H4 Chorismate mutase 2; AtCM2; CM-2; EC 5.4.99.5 from Arabidopsis thaliana (Mouse-ear cress)
Q9S7H4 chorismate mutase (EC 5.4.99.5) from Arabidopsis thaliana
265 amino acids: PaperBLAST, CDD, Compare to cluster

U5D896 chorismate mutase (EC 5.4.99.5) from Amborella trichopoda
292 amino acids: PaperBLAST, CDD, Compare to cluster

W1PFX5 chorismate mutase (EC 5.4.99.5) from Amborella trichopoda
328 amino acids: PaperBLAST, CDD, Compare to cluster

CHMU_TRIPA / A0A0S0FTT9 Chorismate mutase; CM; TpARO7; EC 5.4.99.5 from Trichoderma parareesei (Filamentous fungus)
A0A0S0FTT9 chorismate mutase (EC 5.4.99.5) from Trichoderma parareesei
266 amino acids: PaperBLAST, CDD, Compare to cluster

CMU_ERYQU / A0A5B8NIM2 Chorismate mutase; EqCMU; EC 5.4.99.5 from Erysiphe quercicola (Hevea powdery mildew)
262 amino acids: PaperBLAST, CDD, Compare to cluster

CM1_MAIZE / B4FNK8 Chorismate mutase 1, chloroplastic; ZmCM1; EC 5.4.99.5 from Zea mays (Maize)
312 amino acids: PaperBLAST, CDD, Compare to cluster

CM2_MAIZE / B4FUP5 Chorismate mutase 2, cytosolic; ZmCM2; EC 5.4.99.5 from Zea mays (Maize)
253 amino acids: PaperBLAST, CDD, Compare to cluster

CM1_PETHY / D2CSU4 Chorismate mutase 1, chloroplastic; PhCM1; EC 5.4.99.5 from Petunia hybrida (Petunia)
D2CSU4 chorismate mutase (EC 5.4.99.5) from Petunia x hybrida
324 amino acids: PaperBLAST, CDD, Compare to cluster

CM2_PETHY / D2CSU5 Chorismate mutase 2; PhCM2; EC 5.4.99.5 from Petunia hybrida (Petunia)
D2CSU5 chorismate mutase (EC 5.4.99.5) from Petunia x hybrida
263 amino acids: PaperBLAST, CDD, Compare to cluster

CHMU_EMENI / G5EB37 Chorismate mutase; CM; AnCM; EC 5.4.99.5 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
CH_122283 chorismate mutase; EC 5.4.99.5 from Emericella nidulans
267 amino acids: PaperBLAST, CDD, Compare to cluster

CHMU_YEAST / P32178 Chorismate mutase; CM; EC 5.4.99.5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
256 amino acids: PaperBLAST, CDD, Compare to cluster

CHMU_PICAN / Q9P4D8 Chorismate mutase; CM; EC 5.4.99.5 from Pichia angusta (Yeast) (Hansenula polymorpha)
280 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 181-202 amino acids (not heteromeric)

CHMU_PSEAE / Q9HU05 Monofunctional chorismate mutase; EC 5.4.99.5 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: CM_2
185 amino acids: PaperBLAST, CDD, Compare to cluster

B2JYH9 chorismate mutase (EC 5.4.99.5) from Paraburkholderia phymatum
PFams: CM_2
182 amino acids: PaperBLAST, CDD, Compare to cluster

Q2SY64 chorismate mutase (EC 5.4.99.5) from Burkholderia thailandensis
PFams: CM_2
202 amino acids: PaperBLAST, CDD, Compare to cluster

SCMU_MYCS2 / A0QU81 Secreted chorismate mutase; CM; EC 5.4.99.5 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
PFams: CM_2
181 amino acids: PaperBLAST, CDD, Compare to cluster

SCMU_MYCTU / P9WIB9 Secreted chorismate mutase; CM; *MtCM; EC 5.4.99.5 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: CM_2
199 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 365-386 amino acids (not heteromeric)

C7EXK8 prephenate dehydratase (EC 4.2.1.51); chorismate mutase (EC 5.4.99.5) from Escherichia coli
PFams: CM_2, PDT
386 amino acids: PaperBLAST, CDD, Compare to cluster

b2599 fused chorismate mutase/prephenate dehydratase (EC 5.4.99.5; EC 4.2.1.51) from Escherichia coli K-12 substr. MG1655
P0A9J8 fused chorismate mutase/prephenate dehydratase (EC 5.4.99.5; EC 4.2.1.51) from Escherichia coli (strain K12)
CMPDT_ECOLI / P0A9J8 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51 from Escherichia coli (strain K12)
CH_024084 P-protein; EC 4.2.1.51; EC 5.4.99.5 from Escherichia coli K12
PFams: CM_2, PDT
386 amino acids: PaperBLAST, CDD, Compare to cluster

CMPDT_STUST / P27603 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51 from Stutzerimonas stutzeri (Pseudomonas stutzeri)
PFams: CM_2, PDT, ACT
365 amino acids: PaperBLAST, CDD, Compare to cluster

CMPDT_BUCAI / P57472 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51 from Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
P57472 prephenate dehydratase (EC 4.2.1.51) from Buchnera aphidicola
PFams: CM_2, PDT
385 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 181-186 amino acids (not heteromeric)

CHMU_ENTAG / P42517 Monofunctional chorismate mutase; CM-F; EC 5.4.99.5 from Enterobacter agglomerans (Erwinia herbicola) (Pantoea agglomerans)
PFams: CM_2
181 amino acids: PaperBLAST, CDD, Compare to cluster

SCMU_YERPE / Q7CHH5 Secreted chorismate mutase; CM; *YpCM; EC 5.4.99.5 from Yersinia pestis
Q7CHH5 chorismate mutase (EC 5.4.99.5) from Yersinia pestis
PFams: CM_2
186 amino acids: PaperBLAST, CDD, Compare to cluster

CHMU_SALTM / Q93LJ4 Monofunctional chorismate mutase; EC 5.4.99.5 from Salmonella typhimurium
PFams: CM_2
181 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 5 122-127 amino acids (not heteromeric)

AROH_BACSU / P19080 Chorismate mutase AroH; CM; EC 5.4.99.5 from Bacillus subtilis (strain 168)
PFams: CM_1
127 amino acids: PaperBLAST, CDD, Compare to cluster

AROH_THETH / Q84FH6 Chorismate mutase AroH; EC 5.4.99.5 from Thermus thermophilus
Q84FH6 chorismate mutase (EC 5.4.99.5) from Thermus thermophilus
PFams: CM_1
122 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 6 275-286 amino acids (not heteromeric)

B6C761 chorismate mutase (EC 5.4.99.5) from Globodera rostochiensis
PFams: CM_2
286 amino acids: PaperBLAST, CDD, Compare to cluster

Q3LUE0 chorismate mutase (EC 5.4.99.5) from Heterodera schachtii
PFams: CM_2
275 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 7 367-379 amino acids (not heteromeric)

Echvi_0120 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase / chorismate mutase (EC 2.5.1.54; EC 5.4.99.5) from Echinicola vietnamensis KMM 6221, DSM 17526
PFams: DAHP_synth_1, CM_2
367 amino acids: PaperBLAST, CDD, Compare to cluster

CA265_RS11635 chorismate mutase (EC 5.4.99.5) from Pedobacter sp. GW460-11-11-14-LB5
PFams: DAHP_synth_1, CM_2
379 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 8 373-377 amino acids (not heteromeric)

P43902 prephenate dehydrogenase (EC 1.3.1.12) from Haemophilus influenzae
PFams: CM_2, PDH_N, PDH_C
377 amino acids: PaperBLAST, CDD, Compare to cluster

b2600 fused chorismate mutase/prephenate dehydrogenase (EC 5.4.99.5; EC 1.3.1.12) from Escherichia coli K-12 substr. MG1655
P07023 fused chorismate mutase/prephenate dehydrogenase (EC 5.4.99.5; EC 1.3.1.12) from Escherichia coli (strain K12)
PFams: CM_2, PDH_N, PDH_C
373 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 9 591-620 amino acids (not heteromeric)

O30012 prephenate dehydrogenase (EC 1.3.1.12); prephenate dehydratase (EC 4.2.1.51); chorismate mutase (EC 5.4.99.5) from Archaeoglobus fulgidus
PFams: PDH_N, PDH_C, CM_2, PDT, ACT
620 amino acids: PaperBLAST, CDD, Compare to cluster

Q74NC4 prephenate dehydratase (EC 4.2.1.51) from Nanoarchaeum equitans
PFams: CM_2, PDT, ACT
591 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 10 104-105 amino acids (not heteromeric)

CHMU_MYCTU / P9WIC1 Intracellular chorismate mutase; CM; EC 5.4.99.5 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WIC1 chorismate mutase (EC 5.4.99.5) from Mycobacterium tuberculosis
PFams: CM_2
105 amino acids: PaperBLAST, CDD, Compare to cluster

CHMU_MYCS2 / A0R3N5 Intracellular chorismate mutase; CM; EC 5.4.99.5 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
PFams: CM_2
104 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/8 heteromeric)

A8AAX2 prephenate dehydrogenase (NADP+) (EC 1.3.1.13) from Ignicoccus hospitalis
PFams: CM_2, Rossmann-like, F420_oxidored, NAD_binding_2, PDH_N, PDH_C
348 amino acids: PaperBLAST, CDD

P39912 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54); chorismate mutase (EC 5.4.99.5) from Bacillus subtilis
PFams: CM_2, DAHP_synth_1, NeuB
358 amino acids: PaperBLAST, CDD

PAPB_STRPR / P72541 4-amino-4-deoxychorismate mutase; ADC mutase; EC 5.4.99.67 (from HMM only) from Streptomyces pristinaespiralis
P72541 4-amino-4-deoxychorismate mutase (EC 5.4.99.67) from Streptomyces pristinaespiralis
PFams: CM_2
129 amino acids: PaperBLAST, CDD

MBTI_MYCTU / P9WFX1 Salicylate synthase; Chorismate mutase; CM; Isochorismate synthase/isochorismate lyase; Mycobactin synthase protein; EC 5.4.99.5; EC 4.2.99.21; EC 5.4.4.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WFX1 isochorismate lyase (EC 4.2.99.21); isochorismate synthase (EC 5.4.4.2) from Mycobacterium tuberculosis
PFams: Chorismate_bind
450 amino acids: PaperBLAST, CDD

Q51507 isochorismate pyruvate lyase (EC 4.2.99.21) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PCHB_PSEAE / Q51507 Isochorismate pyruvate lyase; IPL; Chorismate mutase; CM; Salicylate biosynthesis protein; EC 4.2.99.21; EC 5.4.99.5 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q51507 isochorismate lyase (EC 4.2.99.21) from Pseudomonas aeruginosa
PFams: CM_2
101 amino acids: PaperBLAST, CDD

CMU1_USTMA / A0A0D1DWQ2 Secreted chorismate mutase; EC 5.4.99.5 from Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
290 amino acids: PaperBLAST, CDD

CHMU_METJA / Q57696 Chorismate mutase; CM; Monofunctional chorismate mutase AroQ(f); EC 5.4.99.5 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
PFams: CM_2
99 amino acids: PaperBLAST, CDD

F2RB77 4-amino-4-deoxychorismate mutase (EC 5.4.99.67) (from HMM only) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
PFams: CM_2
103 amino acids: PaperBLAST, CDD