Other Characterized Proteins Similar to OAT

GapMind for Amino acid biosynthesis

Other Characterized Proteins Similar to OAT

Finding the characterized proteins for OAT (L-ornithine 5-aminotransferase) in L-proline biosynthesis

Or see clustering for step OAT

Or see all steps for L-proline biosynthesis

Or cluster curated proteins matching a keyword

Definition of OAT

Curated proteins or TIGRFams with EC 2.6.1.13
Curated sequence CH_124176: ornithine aminotransferase
Ignore hits to O30508 when looking for 'other' hits (succinylornithine transaminase (EC 2.6.1.81). Succinylornithine transaminase/acetylornithine aminotransferase; ACOAT; SOAT; Succinylornithine aminotransferase; EC 2.6.1.11; EC 2.6.1.81. succinylornithine transaminase subunit (EC 2.6.1.13; EC 2.6.1.11; EC 2.6.1.81))
Comment: Converts ornithine to glutamate semialdehyde. CH_124176 is annotated as ornithine transaminase but without the EC number; it probably has the same activity. BRENDA annotates AruC from Pseudomonas aeruginosa (O30508) has naving this activity as well, but it's probably not physiologically relevant and the Km is high (10 mM, PMID:238949); so O30508 considered an OAT in GapMind.

Fetched 26 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 5 other characterized sequences. (Found 31 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for OAT.)

ASRAC_PYRHO / O58478 Alanine/serine racemase; ASR; Ala/Ser racemase; EC 5.1.1.-; EC 5.1.1.1 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
PFams: Aminotran_3
474 amino acids: PaperBLAST, CDD, SwissProt::O58478
48% identical to

ORNAT_THEKO / Q5JEW1 Ornithine aminotransferase; Orn-AT; Lysine aminotransferase; Lys-AT; EC 2.6.1.13; EC 2.6.1.36 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
PFams: Aminotran_3
445 amino acids: PaperBLAST, CDD

Q93R93 L-2-aminoadipate semialdehyde transaminase monomer (EC 2.6.1.118) from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
LYSJ_THET2 / Q93R93 [LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.118 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
Q93R93 [amino group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase (EC 2.6.1.118) from Thermus thermophilus
PFams: Aminotran_3
395 amino acids: PaperBLAST, CDD, BRENDA::Q93R93
41% identical to

OAT_BACSU / P38021 Ornithine aminotransferase; OAT; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Bacillus subtilis (strain 168)
PFams: Aminotran_3
401 amino acids: PaperBLAST, CDD

LMRAC_THEKO / Q5JGG6 Leucine/methionine racemase; Leu/Met racemase; EC 5.1.1.-; EC 5.1.1.2 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
PFams: Aminotran_3, Aminotran_1_2
443 amino acids: PaperBLAST, CDD, SwissProt::Q5JGG6
44% identical to

ORNAT_PYRHO / O50131 Ornithine aminotransferase; Orn-AT; Ornithine delta-aminotransferase; EC 2.6.1.13 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
PFams: Aminotran_3
454 amino acids: PaperBLAST, CDD

BARAC_PYRHO / O57878 Broad substrate specificity amino-acid racemase; BAR; EC 5.1.1.10 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
O57878 amino-acid racemase (EC 5.1.1.10) from Pyrococcus horikoshii
PFams: Aminotran_3
466 amino acids: PaperBLAST, CDD, BRENDA::O57878
41% identical to

A0A5B8KQ12 4-aminobutyrate-2-oxoglutarate transaminase (EC 2.6.1.19) from Agrobacterium tumefaciens
PFams: Aminotran_3
426 amino acids: PaperBLAST, CDD, BRENDA::A0A5B8KQ12
41% identical to