Clusters of Characterized Proteins

Clustering the characterized proteins for argC (N-acylglutamylphosphate reductase) in L-proline biosynthesis

Or see other characterized proteins similar to argC

Or see all steps for L-proline biosynthesis

Or cluster curated proteins matching a keyword

Definition of argC

• Curated proteins or TIGRFams with EC 1.2.1.38
• Comment: ArgC includes Bacteroides proteins that probably act on N-succinylglutamylphosphate instead of N-acetylglutamylphosphate (i.e. BT3759)

Fetched 11 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 10 of these sequences

Found 2 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 334-415 amino acids (not heteromeric)

N-ACETYLGLUTPREDUCT-MONOMER N-acetylglutamylphosphate reductase (EC 1.2.1.38)
P11446 N-acetyl-gamma-glutamyl-phosphate reductase; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38
P11446 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38)
N-ACETYLGLUTPREDUCT-MONOMER N-acetylglutamylphosphate reductase (EC 1.2.1.38)
PFams: Semialdhyde_dh, Semialdhyde_dhC
334 amino acids: PaperBLAST, CDD, Compare to cluster

P9WPZ9 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38)
PFams: Semialdhyde_dh, Semialdhyde_dhC
352 amino acids: PaperBLAST, CDD, Compare to cluster

O50146 [LysW]-L-2-aminoadipate 6-phosphate reductase; EC 1.2.1.-
MONOMER-6802 [LysW]-L-2-aminoadipate 6-phosphate reductase (from HMM only)
PFams: Semialdhyde_dh, Semialdhyde_dhC
344 amino acids: PaperBLAST, CDD, Compare to cluster

Q07906 N-acetyl-gamma-glutamyl-phosphate reductase; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38
PFams: Semialdhyde_dh, Semialdhyde_dhC
345 amino acids: PaperBLAST, CDD, Compare to cluster

Q6AV34 Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38
PFams: Semialdhyde_dh, Semialdhyde_dhC
415 amino acids: PaperBLAST, CDD, Compare to cluster

Q93Z70 Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38
PFams: Semialdhyde_dh, Semialdhyde_dhC
401 amino acids: PaperBLAST, CDD, Compare to cluster

MONOMER-18313 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase (EC 1.2.1.38)
PFams: Semialdhyde_dh, Semialdhyde_dhC
350 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 857-885 amino acids (not heteromeric)

Q01217 Protein ARG5,6, mitochondrial; EC 1.2.1.38; EC 2.7.2.8
Q01217 acetylglutamate kinase (EC 2.7.2.8)
PFams: AA_kinase, NAT, Semialdhyde_dh, Semialdhyde_dhC
863 amino acids: PaperBLAST, CDD, Compare to cluster

CH_123299 arginine biosynthetic enzyme activities (from HMM only)
PFams: AA_kinase, NAT, Semialdhyde_dh
857 amino acids: PaperBLAST, CDD, Compare to cluster

CH_125213 N-acetyl-gamma-glutamyl-phosphate reductase/acetylglutamate kinase; EC 1.2.1.38; EC 2.7.2.8
PFams: AA_kinase, NAT, Semialdhyde_dh
885 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

C7ACH5 lysine racemase (EC 5.1.1.5) (low-coverage HMM hit)
PFams: MR_MLE_N, Semialdhyde_dh
393 amino acids: PaperBLAST, CDD