Other Characterized Proteins Similar to lysZ

GapMind for Amino acid biosynthesis

Other Characterized Proteins Similar to lysZ

Finding the characterized proteins for lysZ ([LysW]-glutamate kinase) in L-proline biosynthesis

Or see clustering for step lysZ

Or see all steps for L-proline biosynthesis

Or cluster curated proteins matching a keyword

Definition of lysZ

Curated proteins or TIGRFams with EC 2.7.2.19
UniProt sequence Q5JFW2: RecName: Full=Putative [LysW]-aminoadipate/[LysW]-glutamate kinase {ECO:0000256|HAMAP-Rule:MF_02082}; EC=2.7.2.17 {ECO:0000256|HAMAP-Rule:MF_02082}; EC=2.7.2.19 {ECO:0000256|HAMAP-Rule:MF_02082};
Predicted: UniProt sequence D4GYN9: RecName: Full=Putative [LysW]-aminoadipate/[LysW]-glutamate kinase {ECO:0000256|HAMAP-Rule:MF_02082}; EC=2.7.2.17 {ECO:0000256|HAMAP-Rule:MF_02082}; EC=2.7.2.19 {ECO:0000256|HAMAP-Rule:MF_02082};
Comment: TK0276 from Thermococcus kodakarensis (Q5JFW2) is bifunctional, for lysine and ornithine synthesis (PMC5076833). In Haloferax volcanii, the putative [LysW]-glutamate kinase (HVO_RS04915, D4GYN9) is in a conserved operon with LysW and with other arginine synthesis genes; this protein is more similar to a characterized [LysW]-2-aminoadipate 6-kinase, but haloarchaea do not use the aminoadipate pathway (PMC93780, PMC8305020).

Fetched 3 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 2 other characterized sequences. (Found 3 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for lysZ.)

LYSZ_THET2 / O50147 [LysW]-aminoadipate kinase; EC 2.7.2.17 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
PFams: AA_kinase
269 amino acids: PaperBLAST, CDD, SwissProt::O50147
41% identical to

D4GYN9 Putative [LysW]-aminoadipate/[LysW]-glutamate kinase {ECO:0000256|HAMAP-Rule:MF_02082}; EC=2.7.2.17 {ECO:0000256|HAMAP-Rule:MF_02082}; EC=2.7.2.19 {ECO:0000256|HAMAP-Rule:MF_02082}
327 amino acids: PaperBLAST, CDD

Q5SH27 [LysW]-L-2-aminoadipate 6-kinase monomer (EC 2.7.2.17) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
PFams: AA_kinase
269 amino acids: PaperBLAST, CDD, metacyc::MONOMER-6801
41% identical to