GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for proA (gamma-glutamylphosphate reductase) in L-proline biosynthesis

Or see other characterized proteins similar to proA

Or see all steps for L-proline biosynthesis

Or cluster curated proteins matching a keyword

Definition of proA

Fetched 9 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 9 of these sequences

Found 2 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 716-795 amino acids (not heteromeric)

P5CS2_ORYSJ / Q941T1 Delta-1-pyrroline-5-carboxylate synthase 2; OsP5CS2; EC 2.7.2.11; EC 1.2.1.41 from Oryza sativa subsp. japonica (Rice)
Q941T1 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Oryza sativa
PFams: AA_kinase, Aldedh
735 amino acids: PaperBLAST, CDD, Compare to cluster

P5CS_MOUSE / Q9Z110 Delta-1-pyrroline-5-carboxylate synthase; P5CS; Aldehyde dehydrogenase family 18 member A1; EC 2.7.2.11; EC 1.2.1.41 from Mus musculus (Mouse)
Q9Z110 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Mus musculus
PFams: AA_kinase, Aldedh
795 amino acids: PaperBLAST, CDD, Compare to cluster

P5CS1_ORYSJ / O04226 Delta-1-pyrroline-5-carboxylate synthase 1; OsP5CS1; EC 2.7.2.11; EC 1.2.1.41 from Oryza sativa subsp. japonica (Rice)
PFams: AA_kinase, Aldedh
716 amino acids: PaperBLAST, CDD, Compare to cluster

P54886 δ-1-pyrroline-5-carboxylate synthase (EC 1.2.1.41; EC 2.7.2.11) from Homo sapiens
P5CS_HUMAN / P54886 Delta-1-pyrroline-5-carboxylate synthase; P5CS; Aldehyde dehydrogenase family 18 member A1; EC 2.7.2.11; EC 1.2.1.41 from Homo sapiens (Human)
PFams: AA_kinase, Aldedh
795 amino acids: PaperBLAST, CDD, Compare to cluster

P54887 δ1-pyrroline-5-carboxylate synthetase (EC 1.2.1.41; EC 2.7.2.11) from Arabidopsis thaliana
PFams: AA_kinase, Aldedh
717 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 399-456 amino acids (not heteromeric)

A7Y114 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Halobacillus halophilus
PFams: Aldedh
420 amino acids: PaperBLAST, CDD, Compare to cluster

b0243 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Escherichia coli K-12 substr. MG1655
P07004 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Escherichia coli (strain K12)
PROA_ECOLI / P07004 Gamma-glutamyl phosphate reductase; GPR; Glutamate-5-semialdehyde dehydrogenase; Glutamyl-gamma-semialdehyde dehydrogenase; GSA dehydrogenase; EC 1.2.1.41 from Escherichia coli (strain K12)
PFams: Aldedh
417 amino acids: PaperBLAST, CDD, Compare to cluster

PROA_YEAST / P54885 Gamma-glutamyl phosphate reductase; GPR; Glutamate-5-semialdehyde dehydrogenase; GSA dehydrogenase; Glutamyl-gamma-semialdehyde dehydrogenase; EC 1.2.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Aldedh
456 amino acids: PaperBLAST, CDD, Compare to cluster

Echvi_2633 gamma-glutamylphosphate reductase (EC 1.2.1.41) from Echinicola vietnamensis KMM 6221, DSM 17526
PFams: Aldedh, Aldedh
399 amino acids: PaperBLAST, CDD, Compare to cluster