Other Characterized Proteins Similar to serC
Finding the characterized proteins for serC (3-phosphoserine aminotransferase) in L-serine biosynthesis
Or see clustering for step serC
Or see all steps for L-serine biosynthesis
Or cluster curated proteins matching a keyword
Definition of serC
- Curated proteins or TIGRFams with EC 2.6.1.52
- UniProt sequence Y959_METJA: RecName: Full=Uncharacterized aminotransferase MJ0959; EC=2.6.1.-;
- UniProt sequence Q2FXK2: RecName: Full=Aminotransferase class V domain-containing protein {ECO:0000259|Pfam:PF00266};
- Predicted: UniProt sequence A5I0W7: SubName: Full=Serine--glyoxylate aminotransferase {ECO:0000313|EMBL:CAL82678.1}; EC=2.6.1.45 {ECO:0000313|EMBL:CAL82678.1};
- Predicted: UniProt sequence A0A843E9R6: SubName: Full=Alanine--glyoxylate aminotransferase family protein {ECO:0000313|EMBL:MBO5653953.1};
- Predicted: UniProt sequence A0A1T4W7T3: SubName: Full=Aspartate aminotransferase {ECO:0000313|EMBL:SKA73374.1};
- Predicted: UniProt sequence A0A097AUI2: SubName: Full=Serine-pyruvate aminotransferase {ECO:0000313|EMBL:AIS53461.1}; EC=2.6.1.51 {ECO:0000313|EMBL:AIS53461.1};
- Comment: MJ0959 (Y959_METJA) is phosphoserine transaminase (PMID:17071763). A mutant in the putative aminotransferase SAUSA300_1669 = Q2FXK2 is a serine auxotroph (PMC5912478), and this gene is conserved near other serine synthesis genes (SerC2 in PMC9026213). A5I0W7 is a putative aminotransferase and is conserved near serine synthesis genes (SerC3 in PMC9026213; also see CDIF630erm_01130 in PMC6110889). Some moderately diverged SerC3 homologs are also conserved near serine synthesis genes (A3204_00420, similar to A0A843E9R6; G452_RS0102660, similar to A0A1T4W7T3). In Thermoanaerobacter kivui LKT-1, a putative transaminase (TKV_RS11400, A0A097AUI2) is encoded next to serA; by homology, it might be a serine:pyruvate aminotransferase or a phosphoserine transaminase; given the conserved proximity to serA, we predicted that it is serC.
Fetched 24 sequences
Running ublast to find other characterized proteins with 40% identity and 70% coverage
Found hits to 1 other characterized sequences. (Found 19 hits including self hits.)
Close sequences
(Sequences that are similar to these will not be high-confidence candidates for serC.)
SAT_THEMA / Q9X1C0 Serine-pyruvate aminotransferase; SAT; EC 2.6.1.51 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
PFams: Aminotran_5, Aminotran_1_2, Cys_Met_Meta_PP, DegT_DnrJ_EryC1
384 amino acids: PaperBLAST, CDD, SwissProt::Q9X1C0
43% identical to
P74281 serine—glyoxylate transaminase (EC 2.6.1.52) from Synechocystis sp. (strain PCC 6803 / Kazusa)
P74281 phosphoserine transaminase (EC 2.6.1.52) from Synechocystis sp.
PFams: Aminotran_5
384 amino acids: PaperBLAST, CDD