Other Characterized Proteins Similar to asp-kinase

Finding the characterized proteins for asp-kinase (aspartate kinase) in L-threonine biosynthesis

Or see clustering for step asp-kinase

Or see all steps for L-threonine biosynthesis

Or cluster curated proteins matching a keyword

Definition of asp-kinase

• Curated proteins or TIGRFams with EC 2.7.2.4
• Ignore hits to O63067 when looking for 'other' hits (homoserine dehydrogenase (EC 1.1.1.3))
• Comment: For BRENDA::O63067 -- the paper describes a monofunctional hom but the sequence of O63067 is much longer and has a close homolog of functional aspartate kinase (due to alternative splicing?)

Fetched 29 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 1 other characterized sequences. (Found 30 hits including self hits.)

Removing ignored items reduces this to 0 close sequences.

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for asp-kinase.)

O63067 homoserine dehydrogenase (EC 1.1.1.3)
PFams: AA_kinase, ACT, ACT_7, ACT, NAD_binding_3, Homoserine_dh
916 amino acids: PaperBLAST, CDD, BRENDA::O63067
76% identical to

O81852 Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic; AK-HD 2; AK-HSDH 2; Beta-aspartyl phosphate homoserine 2; EC 2.7.2.4; EC 1.1.1.3
PFams: AA_kinase, ACT, ACT_7, ACT, NAD_binding_3, Homoserine_dh
916 amino acids: PaperBLAST, CDD