Other Characterized Proteins Similar to hom

Finding the characterized proteins for hom (homoserine dehydrogenase) in L-threonine biosynthesis

Or see clustering for step hom

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Definition of hom

• Curated proteins or TIGRFams with EC 1.1.1.3
• UniProt sequence A0A1L6J6Q3: RecName: Full=Homoserine dehydrogenase {ECO:0000256|ARBA:ARBA00013213, ECO:0000256|RuleBase:RU000579}; EC=1.1.1.3 {ECO:0000256|ARBA:ARBA00013213, ECO:0000256|RuleBase:RU000579};
• UniProt sequence Q8A541_BACTN: SubName: Full=Aspartokinase/homoserine dehydrogenase {ECO:0000313|EMBL:AAO77510.1};
• UniProt sequence B8DRS3_DESVM: RecName: Full=Homoserine dehydrogenase {ECO:0000256|ARBA:ARBA00013213, ECO:0000256|RuleBase:RU000579}; EC=1.1.1.3 {ECO:0000256|ARBA:ARBA00013213, ECO:0000256|RuleBase:RU000579};
• UniProt sequence A0A168MV81: RecName: Full=homoserine dehydrogenase {ECO:0000256|ARBA:ARBA00013213}; EC=1.1.1.3 {ECO:0000256|ARBA:ARBA00013213};
• Comment: Ga0059261_2711 (A0A1L6J6Q3) from Sphingomonas koreensis DSMZ 15582 is distant from characterized homoserine dehydrogenases and is confirmed by fitness data. BT2403 from Bacteroides thetaiotaomicron (Q8A541_BACTN) is a fusion of aspartate kinase and homoserine dehydrogenase. The homoserine dehydrogenase portion is somewhat diverged. Its role is confirmed by strong cofitness with threonine synthase (the defined media for B. thetaiotaomicron included methionine). DvMF_1412 from Desulfovibrio vulgaris Miyazaki F (B8DRS3_DESVM) is a somewhat diverged homoserine dehydrogenase; it has auxotrophic phenotypes. A0A168MV81 from Brevundimonas is a somewhat diverged homoserine dehydrogenase (fused to aspartate kinase); it has auxotrophic phenotypes.

Fetched 33 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 0 other characterized sequences. (Found 29 hits including self hits.)