GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for thrC (threonine synthase) in L-threonine biosynthesis

Or see other characterized proteins similar to thrC

Or see all steps for L-threonine biosynthesis

Or cluster curated proteins matching a keyword

Definition of thrC

Fetched 16 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 16 of these sequences

Found 2 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 428-514 amino acids (not heteromeric)

Q8YFS0 threonine synthase (EC 4.2.3.1) from Brucella melitensis
PFams: Thr_synth_N, PALP
463 amino acids: PaperBLAST, CDD, Compare to cluster

b0004 threonine synthase (EC 4.2.3.1) from Escherichia coli K-12 substr. MG1655
P00934 threonine synthase (EC 4.2.3.1) from Escherichia coli (strain K12)
THRC_ECOLI / P00934 Threonine synthase; TS; EC 4.2.3.1 from Escherichia coli (strain K12)
P00934 threonine synthase (EC 4.2.3.1) from Escherichia coli
GB|BAB96581.1 threonine synthase; EC 4.2.3.1 from Escherichia coli
PFams: Thr_synth_N, PALP
428 amino acids: PaperBLAST, CDD, Compare to cluster

THRC_YEAST / P16120 Threonine synthase; TS; EC 4.2.3.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P16120 threonine synthase (EC 4.2.3.1) from Saccharomyces cerevisiae
PFams: Thr_synth_N, PALP
514 amino acids: PaperBLAST, CDD, Compare to cluster

Q2SWH9 threonine synthase (EC 4.2.3.1) from Burkholderia thailandensis
PFams: Thr_synth_N, PALP
483 amino acids: PaperBLAST, CDD, Compare to cluster

THRC_CORGL / P23669 Threonine synthase; TS; EC 4.2.3.1 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: Thr_synth_N, PALP
481 amino acids: PaperBLAST, CDD, Compare to cluster

THNS2_MOUSE / Q80W22 Threonine synthase-like 2; TSH2; mTSH2; EC 4.2.3.- (from HMM only) from Mus musculus (Mouse)
PFams: Thr_synth_N, PALP
483 amino acids: PaperBLAST, CDD, Compare to cluster

THNS2_HUMAN / Q86YJ6 Threonine synthase-like 2; TSH2; Secreted osteoclastogenic factor of activated T-cells; SOFAT; EC 4.2.3.- (from HMM only) from Homo sapiens (Human)
PFams: Thr_synth_N, PALP
484 amino acids: PaperBLAST, CDD, Compare to cluster

A0A1I2JHD2_9GAMM Threonine synthase
441 amino acids: PaperBLAST, CDD, Compare to cluster

N515DRAFT_0575 threonine synthase (EC 4.2.3.1) from Dyella japonica UNC79MFTsu3.2
PFams: Thr_synth_N, PALP
441 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 351-516 amino acids (not heteromeric)

THRC_METAC / Q8TQD4 Threonine synthase; TS; EC 4.2.3.1 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
GB|AAM05023.1 threonine synthase; EC 4.2.3.1 from Methanosarcina acetivorans C2A
PFams: PALP
405 amino acids: PaperBLAST, CDD, Compare to cluster

O66740 threonine synthase (EC 4.2.3.1) from Aquifex aeolicus
PFams: PALP
352 amino acids: PaperBLAST, CDD, Compare to cluster

P83823 threonine synthase (EC 4.2.3.1) from Thermus thermophilus
Q5SL02 threonine synthase (EC 4.2.3.1) from Thermus thermophilus
PFams: PALP
351 amino acids: PaperBLAST, CDD, Compare to cluster

THRC_MYCTU / P9WG59 Threonine synthase; TS; EC 4.2.3.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WG59 threonine synthase (EC 4.2.3.1) from Mycobacterium tuberculosis
PFams: PALP
360 amino acids: PaperBLAST, CDD, Compare to cluster

THRC2_ARATH / Q9SSP5 Threonine synthase 2, chloroplastic; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress)
PFams: PALP
516 amino acids: PaperBLAST, CDD, Compare to cluster

DvMF_1945 threonine synthase (EC 4.2.3.1) from Desulfovibrio vulgaris Miyazaki F
PFams: PALP
492 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

THRC1_ARATH / Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress)
PFams: PALP
526 amino acids: PaperBLAST, CDD
(similar to SwissProt::Q9SSP5 from Cluster 2, but similarity to seed sequence is below thresholds)