Clusters of Characterized Proteins

Clustering the characterized proteins for thrC (threonine synthase) in L-threonine biosynthesis

Or see other characterized proteins similar to thrC

Or see all steps for L-threonine biosynthesis

Or cluster curated proteins matching a keyword

Definition of thrC

• Curated proteins or TIGRFams with EC 4.2.3.1
• UniProt sequence A0A1I2JHD2_9GAMM: SubName: Full=Threonine synthase {ECO:0000313|EMBL:SFF54252.1};
• Comment: N515DRAFT_0575 (A0A1I2JHD2_9GAMM) from Dyella japonica UNC79MFTsu3.2 is somewhat diverged; mutants in this gene are auxotrophic.

Fetched 11 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 11 of these sequences

Found 2 clusters of similar sequences. Another 2 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 428-514 amino acids (not heteromeric)

P16120 Threonine synthase; TS; EC 4.2.3.1
PFams: Thr_synth_N, PALP
514 amino acids: PaperBLAST, CDD, Compare to cluster

THRESYN-MONOMER threonine synthase (EC 4.2.3.1)
P00934 Threonine synthase; TS; EC 4.2.3.1
THRESYN-MONOMER threonine synthase (EC 4.2.3.1)
CH_002114 threonine synthase; EC 4.2.3.1
PFams: Thr_synth_N, PALP
428 amino acids: PaperBLAST, CDD, Compare to cluster

P23669 Threonine synthase; TS; EC 4.2.3.1
PFams: Thr_synth_N, PALP
481 amino acids: PaperBLAST, CDD, Compare to cluster

Q80W22 Threonine synthase-like 2; TSH2; mTSH2; EC 4.2.3.- (from HMM only)
PFams: Thr_synth_N, PALP
483 amino acids: PaperBLAST, CDD, Compare to cluster

Q86YJ6 Threonine synthase-like 2; TSH2; Secreted osteoclastogenic factor of activated T-cells; SOFAT; EC 4.2.3.- (from HMM only)
PFams: Thr_synth_N, PALP
484 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 351-516 amino acids (not heteromeric)

Q8TQD4 Threonine synthase; TS; EC 4.2.3.1
CH_107419 threonine synthase; EC 4.2.3.1
PFams: PALP
405 amino acids: PaperBLAST, CDD, Compare to cluster

P9WG59 Threonine synthase; TS; EC 4.2.3.1
P9WG59 threonine synthase (EC 4.2.3.1)
PFams: PALP
360 amino acids: PaperBLAST, CDD, Compare to cluster

Q5SL02 threonine synthase (EC 4.2.3.1)
PFams: PALP
351 amino acids: PaperBLAST, CDD, Compare to cluster

Q9SSP5 Threonine synthase 2, chloroplastic; EC 4.2.3.1
PFams: PALP
516 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/2 heteromeric)

Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1
PFams: PALP
526 amino acids: PaperBLAST, CDD
(similar to SwissProt::Q9SSP5 from Cluster 2, but similarity to seed sequence is below thresholds)

A0A1I2JHD2_9GAMM Threonine synthase
441 amino acids: PaperBLAST, CDD
(similar to CharProtDB::CH_002114 from Cluster 1, but similarity to seed sequence is below thresholds)