Other Characterized Proteins Similar to trpD

GapMind for Amino acid biosynthesis

Other Characterized Proteins Similar to trpD_1

Finding the characterized proteins for trpD_1 (glutamine amidotransferase of anthranilate synthase) in L-tryptophan biosynthesis

Or see clustering for step trpD_1

Or see all steps for L-tryptophan biosynthesis

Or cluster curated proteins matching a keyword

Definition of trpD_1

HMM TIGR00566
Curated proteins matching anthranilate synthase component 2
Curated proteins matching anthranilate synthase component II
Curated proteins matching anthranilate synthase beta subunit
UniProt sequence Q8AAD4_BACTN: SubName: Full=Anthranilate synthase component II {ECO:0000313|EMBL:AAO75638.1};
UniProt sequence A0A1X9ZDE4_9SPHI: SubName: Full=Aminodeoxychorismate/anthranilate synthase component II {ECO:0000313|EMBL:ARS43103.1};
UniProt sequence Q72EV2_DESVH: SubName: Full=Anthranilate synthase, glutamine amidotransferase component {ECO:0000313|EMBL:AAS94949.1}; EC=4.1.3.27 {ECO:0000313|EMBL:AAS94949.1};
UniProt sequence B8DM46_DESVM: SubName: Full=Glutamine amidotransferase of anthranilate synthase {ECO:0000313|EMBL:ACL08690.1};
Ignore hits to items matching EC 4.1.3.27 when looking for 'other' hits
Ignore hits to items matching EC 2.6.1.85 when looking for 'other' hits
Comment: This component of anthranilate synthase is also known as the beta subunit or component II. Note that E. coli TrpD is this component fused to anthranilate phosphoribosyltransferase (which is described separately). Some proteins are components of both anthranilate synthase and 4-amino-4-deoxychorismate synthase (EC 2.6.1.85). Similarly, TIGR00566 also matches the amidotransferase component of para-aminobenzoate synthase. BT0531 (Q8AAD4_BACTN) and CA265_RS22895 (A0A1X9ZDE4_9SPHI) are also component II Similarly for DVU0466 (Q72EV2_DESVH) and DvMF_1745 (B8DM46_DESVM).

Fetched 16 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 9 other characterized sequences. (Found 21 hits including self hits.)

Removing ignored items reduces this to 0 close sequences.

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for trpD_1.)

b1263 anthranilate synthase subunit TrpD (EC 2.4.2.18; EC 4.1.3.27) from Escherichia coli K-12 substr. MG1655
P00904 anthranilate synthase subunit TrpD (EC 2.4.2.18) from Escherichia coli (strain K12)
TRPGD_ECOLI / P00904 Bifunctional protein TrpGD; EC 4.1.3.27; EC 2.4.2.18 from Escherichia coli (strain K12)
PFams: GATase, Peptidase_C26, Glycos_trans_3N, Glycos_transf_3
Heteromeric, 531 amino acids: PaperBLAST, CDD, SwissProt::P00904
81% identical to

TRPG_SERMA / P00900 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Serratia marcescens
PFams: GATase, Peptidase_C26
Heteromeric, 193 amino acids: PaperBLAST, CDD

TRPGD_SALTY / P00905 Bifunctional protein TrpGD; EC 4.1.3.27; EC 2.4.2.18 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: GATase, Peptidase_C26, Glycos_trans_3N, Glycos_transf_3
531 amino acids: PaperBLAST, CDD, SwissProt::P00905
80% identical to

b3360 aminodeoxychorismate synthase subunit 2 (EC 2.6.1.85) from Escherichia coli K-12 substr. MG1655
P00903 aminodeoxychorismate synthase subunit 2 (EC 2.6.1.85) from Escherichia coli (strain K12)
PABA_ECOLI / P00903 Aminodeoxychorismate synthase component 2; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 2; Aminodeoxychorismate synthase, glutamine amidotransferase component; EC 2.6.1.85 from Escherichia coli (strain K12)
P00903 aminodeoxychorismate synthase (EC 2.6.1.85); 2-amino-4-deoxychorismate synthase (EC 2.6.1.86) from Escherichia coli
PFams: GATase, Peptidase_C26
Heteromeric, 187 amino acids: PaperBLAST, CDD, BRENDA::P00903
67% identical to

P20576 anthranilate synthase β subunit (EC 4.1.3.27) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
TRPG_PSEAE / P20576 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
P20576 anthranilate synthase (subunit 2/2) (EC 4.1.3.27) from Pseudomonas aeruginosa
PFams: GATase, Peptidase_C26
Heteromeric, 201 amino acids: PaperBLAST, CDD

P32483 4-amino-4-deoxychorismate synthase (EC 2.6.1.85) from Streptomyces griseus
ADCS_STRGR / P32483 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; p-aminobenzoic acid synthase; PABA synthase; EC 2.6.1.85 from Streptomyces griseus
PFams: GATase, Peptidase_C26, Anth_synt_I_N, Chorismate_bind
723 amino acids: PaperBLAST, CDD, SwissProt::P32483
51% identical to

B8DM46_DESVM Glutamine amidotransferase of anthranilate synthase
192 amino acids: PaperBLAST, CDD

TRPG_YEAST / P00937 Multifunctional tryptophan biosynthesis protein; EC 4.1.3.27; EC 4.1.1.48 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: GATase, Peptidase_C26, IGPS, QRPTase_C
484 amino acids: PaperBLAST, CDD, SwissProt::P00937
49% identical to

TRPG_PSEPU / P00901 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Pseudomonas putida (Arthrobacter siderocapsulatus)
PFams: GATase, Peptidase_C26
Heteromeric, 198 amino acids: PaperBLAST, CDD

ADCS_STRPR / P72539 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; EC 2.6.1.85 from Streptomyces pristinaespiralis
PFams: GATase, Peptidase_C26, Anth_synt_I_N, Chorismate_bind
719 amino acids: PaperBLAST, CDD, SwissProt::P72539
50% identical to

B8DM46_DESVM Glutamine amidotransferase of anthranilate synthase
192 amino acids: PaperBLAST, CDD

F2RB79 4-amino-4-deoxychorismate synthase (EC 2.6.1.85) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
ADCS_STRVP / F2RB79 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; p-aminobenzoate synthase; EC 2.6.1.85 from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
PFams: GATase, Peptidase_C26, Anth_synt_I_N, Chorismate_bind
686 amino acids: PaperBLAST, CDD, SwissProt::F2RB79
49% identical to

TRPG_AZOBR / P26922 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Azospirillum brasilense
PFams: GATase, Peptidase_C26
Heteromeric, 196 amino acids: PaperBLAST, CDD

Q6TAS3 aminodeoxychorismate synthase (EC 2.6.1.85) from Solanum lycopersicum
ADCS_SOLLC / Q6TAS3 Aminodeoxychorismate synthase, chloroplastic; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; EC 2.6.1.85 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
PFams: GATase, GATase, Anth_synt_I_N, Chorismate_bind
902 amino acids: PaperBLAST, CDD, SwissProt::Q6TAS3
41% identical to

P28819 4-amino-4-deoxychorismate synthase; anthranilate synthase (subunit II) (EC 2.6.1.123) from Bacillus subtilis (strain 168)
PABA_BACSU / P28819 Aminodeoxychorismate/anthranilate synthase component 2; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 2; Aminodeoxychorismate synthase, glutamine amidotransferase component; EC 2.6.1.85; EC 4.1.3.27 from Bacillus subtilis (strain 168)
PFams: GATase, Peptidase_C26
Heteromeric, 194 amino acids: PaperBLAST, CDD

Q8LPN3 aminodeoxychorismate synthase (EC 2.6.1.85) from Arabidopsis thaliana
ADCS_ARATH / Q8LPN3 Aminodeoxychorismate synthase, chloroplastic; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; Protein EMBRYO DEFFECTIVE 1997; EC 2.6.1.85 from Arabidopsis thaliana (Mouse-ear cress)
PFams: GATase, GATase, Anth_synt_I_N, Chorismate_bind
919 amino acids: PaperBLAST, CDD, SwissProt::Q8LPN3
45% identical to

B8DM46_DESVM Glutamine amidotransferase of anthranilate synthase
192 amino acids: PaperBLAST, CDD