Clusters of Characterized Proteins

GapMind for Amino acid biosynthesis

Clusters of Characterized Proteins

Clustering the characterized proteins for trpE (anthranilate synthase subunit TrpE) in L-tryptophan biosynthesis

Or see other characterized proteins similar to trpE

Or see all steps for L-tryptophan biosynthesis

Or cluster curated proteins matching a keyword

Definition of trpE

HMM TIGR00564
HMM TIGR00565
HMM TIGR01820
Curated proteins matching anthranilate synthase component 1
Curated proteins matching anthranilate synthase component I
Curated proteins matching anthranilate synthase alpha subunit
UniProt sequence Q8AAD3_BACTN: SubName: Full=Anthranilate synthase component I {ECO:0000313|EMBL:AAO75639.1};
UniProt sequence A0A1X9ZB07_9SPHI: SubName: Full=Anthranilate synthase component I {ECO:0000313|EMBL:ARS42349.1};
UniProt sequence Q72EV3_DESVH: SubName: Full=Anthranilate synthase, component I {ECO:0000313|EMBL:AAS94948.1};
UniProt sequence B8DM47_DESVM: SubName: Full=Anthranilate synthase {ECO:0000313|EMBL:ACL08691.1}; EC=4.1.3.27 {ECO:0000313|EMBL:ACL08691.1};
Ignore hits to items matching EC 4.1.3.27 when looking for 'other' hits
Comment: This component of anthranilate synthase is also known as the alpha subunit or component I. BT0532 (Q8AAD3_BACTN) and CA265_RS22890 (A0A1X9ZB07_9SPHI) are also component I. Similarly for DVU0465 (Q72EV3_DESVH) and DvMF_1746 (B8DM47_DESVM). Some related proteins have EC 2.6.1.85 which should perhaps be ignored.

Fetched 16 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 16 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 421-606 amino acids (8/15 heteromeric)

The first sequence in each cluster is the seed.

P20579 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27
PFams: Anth_synt_I_N, Chorismate_bind
Heteromeric, 493 amino acids: PaperBLAST, CDD, Compare to cluster

P00897 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27
P00897 anthranilate synthase (subunit 2/2) (EC 4.1.3.27)
PFams: Anth_synt_I_N, Chorismate_bind
Heteromeric, 519 amino acids: PaperBLAST, CDD, Compare to cluster

P20580 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27
P20580 anthranilate synthase (EC 4.1.3.27)
PFams: Anth_synt_I_N, Chorismate_bind
Heteromeric, 492 amino acids: PaperBLAST, CDD, Compare to cluster

Q06128 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27
Q06128 anthranilate synthase (subunit 2/2) (EC 4.1.3.27)
MONOMER-3603 anthranilate synthase α subunit (EC 4.1.3.27)
PFams: Anth_synt_I_N, Chorismate_bind
Heteromeric, 421 amino acids: PaperBLAST, CDD, Compare to cluster

CH_008302 anthranilate synthase component I; EC 4.1.3.27
PFams: Anth_synt_I_N, Chorismate_bind
462 amino acids: PaperBLAST, CDD, Compare to cluster

ANTHRANSYNCOMPI-MONOMER anthranilate synthase subunit TrpE (EC 4.1.3.27)
P00895 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27
PFams: Anth_synt_I_N, Chorismate_bind
Heteromeric, 520 amino acids: PaperBLAST, CDD, Compare to cluster

P00898 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27
PFams: Anth_synt_I_N, Chorismate_bind
520 amino acids: PaperBLAST, CDD, Compare to cluster

P00899 Anthranilate synthase component 1; Anthranilate synthase component I; EC 4.1.3.27
PFams: Anth_synt_I_N, Chorismate_bind
507 amino acids: PaperBLAST, CDD, Compare to cluster

P32068 Anthranilate synthase alpha subunit 1, chloroplastic; Anthranilate synthase component 1-1; Anthranilate synthase component I-1; Protein A-METHYL TRYPTOPHAN RESISTANT 1; Protein JASMONATE-INDUCED DEFECTIVE LATERAL ROOT 1; Protein TRYPTOPHAN BIOSYNTHESIS 5; Protein WEAK ETHYLENE INSENSITIVE 2; EC 4.1.3.27
PFams: Anth_synt_I_N, Chorismate_bind
Heteromeric, 595 amino acids: PaperBLAST, CDD, Compare to cluster

Q94GF1 Anthranilate synthase alpha subunit 1, chloroplastic; OsASA1; EC 4.1.3.27
PFams: Anth_synt_I_N, Chorismate_bind
Heteromeric, 577 amino acids: PaperBLAST, CDD, Compare to cluster

Q9XJ29 Anthranilate synthase alpha subunit 2, chloroplastic; OsASA2; EC 4.1.3.27
PFams: Anth_synt_I_N, Chorismate_bind
Heteromeric, 606 amino acids: PaperBLAST, CDD, Compare to cluster

A0A1X9ZB07_9SPHI Anthranilate synthase component I
466 amino acids: PaperBLAST, CDD, Compare to cluster

B8DM47_DESVM Anthranilate synthase; EC=4.1.3.27
520 amino acids: PaperBLAST, CDD, Compare to cluster

Q72EV3_DESVH Anthranilate synthase, component I
532 amino acids: PaperBLAST, CDD, Compare to cluster

Q8AAD3_BACTN Anthranilate synthase component I
468 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (1/1 heteromeric)

P09785 Anthranilate synthase component 1, pyocyanine specific; AS; ASI; EC 4.1.3.27
P09785 anthranilate synthase (subunit 2/2) (EC 4.1.3.27)
PFams: Anth_synt_I_N, Chorismate_bind
Heteromeric, 530 amino acids: PaperBLAST, CDD
(similar to BRENDA::P00897 from Cluster 1, but similarity to seed sequence is below thresholds)