GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for PAH (phenylalanine hydroxylase) in L-tyrosine biosynthesis

Or see other characterized proteins similar to PAH

Or see all steps for L-tyrosine biosynthesis

Or cluster curated proteins matching a keyword

Definition of PAH

Fetched 16 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 14 of these sequences

Found 2 clusters of similar sequences. Another 2 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 261-297 amino acids (not heteromeric)

acidovorax_3H11:Ac3H11_1847 Phenylalanine 4-monooxygenase (EC 1.14.16.1)
PFams: Biopterin_H
290 amino acids: PaperBLAST, CDD, Compare to cluster

MONOMER-12067 phenylalanine hydroxylase (EC 1.14.16.1)
P30967 phenylalanine 4-monooxygenase (EC 1.14.16.1)
PFams: Biopterin_H
297 amino acids: PaperBLAST, CDD, Compare to cluster

Q47XN7 phenylalanine 4-monooxygenase (EC 1.14.16.1)
PFams: Biopterin_H
267 amino acids: PaperBLAST, CDD, Compare to cluster

MR1:200831 Phenylalanine 4-monooxygenase (EC 1.14.16.1)
PFams: Biopterin_H
271 amino acids: PaperBLAST, CDD, Compare to cluster

pseudo13_GW456_L13:PfGW456L13_4394 Phenylalanine 4-monooxygenase (EC 1.14.16.1)
PFams: Biopterin_H
261 amino acids: PaperBLAST, CDD, Compare to cluster

pseudo3_N2E3:AO353_18585 Phenylalanine 4-monooxygenase (EC 1.14.16.1)
PFams: Biopterin_H
263 amino acids: PaperBLAST, CDD, Compare to cluster

pseudo5_N2C3_1:AO356_03975 Phenylalanine 4-monooxygenase (EC 1.14.16.1)
PFams: Biopterin_H
261 amino acids: PaperBLAST, CDD, Compare to cluster

pseudo6_N2E2:Pf6N2E2_2630 Phenylalanine 4-monooxygenase (EC 1.14.16.1)
PFams: Biopterin_H
261 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 441-457 amino acids (not heteromeric)

HS10374-MONOMER phenylalanine hydroxylase subunit (EC 1.14.16.1)
P00439 Phenylalanine-4-hydroxylase; PAH; Phe-4-monooxygenase; EC 1.14.16.1
P00439 phenylalanine 4-monooxygenase (EC 1.14.16.1)
PFams: ACT, Biopterin_H
452 amino acids: PaperBLAST, CDD, Compare to cluster

P04176 Phenylalanine-4-hydroxylase; PAH; Phe-4-monooxygenase; EC 1.14.16.1
P04176 phenylalanine 4-monooxygenase (EC 1.14.16.1)
PFams: ACT, Biopterin_H
453 amino acids: PaperBLAST, CDD, Compare to cluster

Q8TEY0 phenylalanine 4-monooxygenase (EC 1.14.16.1)
PFams: ACT, Biopterin_H
452 amino acids: PaperBLAST, CDD, Compare to cluster

P16331 Phenylalanine-4-hydroxylase; PAH; Phe-4-monooxygenase; EC 1.14.16.1
PFams: ACT, Biopterin_H
453 amino acids: PaperBLAST, CDD, Compare to cluster

P90925 Phenylalanine-4-hydroxylase; PAH; Biogenic amine synthesis protein 2; Phe-4-monooxygenase; Tryptophan 5-monooxygenase; EC 1.14.16.1; EC 1.14.16.4
PFams: ACT, Biopterin_H
457 amino acids: PaperBLAST, CDD, Compare to cluster

Q54XS1 Phenylalanine-4-hydroxylase; PAH; Phe-4-monooxygenase; Tryptophan 5-hydroxylase; TRH; Tryptophan 5-monooxygenase; EC 1.14.16.1; EC 1.14.16.4
PFams: Biopterin_H
441 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/2 heteromeric)

MONOMER-17816 phenylalanine hydroxylase (EC 1.14.16.1)
PFams: Biopterin_H
361 amino acids: PaperBLAST, CDD

MONOMER-17817 phenylalanine hydroxylase (EC 1.14.16.1)
PFams: Biopterin_H
394 amino acids: PaperBLAST, CDD