Clusters of Characterized Proteins

GapMind for Amino acid biosynthesis

Clusters of Characterized Proteins

Clustering the characterized proteins for cmutase (chorismate mutase) in L-tyrosine biosynthesis

Or see other characterized proteins similar to cmutase

Or see all steps for L-tyrosine biosynthesis

Or cluster curated proteins matching a keyword

Definition of cmutase

Curated proteins or TIGRFams with EC 5.4.99.5
HMM PF01817
Comment: Chorismate mutase is usually fused to prephenate dehydratase, which makes it difficult to find this activity when it is fused to something else. As of March 2019, the PFam does not have any characterized members with other functions

Fetched 30 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 26 of these sequences

Found 9 clusters of similar sequences. Another 4 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 263-340 amino acids (not heteromeric)

D2CSU4 Chorismate mutase (EC 5.4.99.5)
324 amino acids: PaperBLAST, CDD, Compare to cluster

D2CSU5 Chorismate mutase (EC 5.4.99.5)
263 amino acids: PaperBLAST, CDD, Compare to cluster

CH_122283 chorismate mutase; EC 5.4.99.5
267 amino acids: PaperBLAST, CDD, Compare to cluster

P42738 Chorismate mutase 1, chloroplastic; AtCM1; CM-1; EC 5.4.99.5
AT3G29200-MONOMER chorismate mutase (EC 5.4.99.5)
340 amino acids: PaperBLAST, CDD, Compare to cluster

Q9C544 Chorismate mutase 3, chloroplastic; AtCM3; CM-3; EC 5.4.99.5
AT1G69370-MONOMER chorismate mutase (EC 5.4.99.5)
316 amino acids: PaperBLAST, CDD, Compare to cluster

Q9S7H4 Chorismate mutase 2; AtCM2; CM-2; EC 5.4.99.5
AT5G10870-MONOMER chorismate mutase (EC 5.4.99.5)
265 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 365-386 amino acids (not heteromeric)

C7EXK8 prephenate dehydratase (EC 4.2.1.51) (from HMM only)
PFams: CM_2, PDT
386 amino acids: PaperBLAST, CDD, Compare to cluster

P57472 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51
P57472 prephenate dehydratase (EC 4.2.1.51)
PFams: CM_2, PDT
385 amino acids: PaperBLAST, CDD, Compare to cluster

CHORISMUTPREPHENDEHYDRAT-MONOMER fused chorismate mutase/prephenate dehydratase (EC 5.4.99.5; EC 4.2.1.51)
P0A9J8 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51
CH_024084 P-protein; EC 4.2.1.51; EC 5.4.99.5
PFams: CM_2, PDT
386 amino acids: PaperBLAST, CDD, Compare to cluster

P27603 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51
PFams: CM_2, PDT, ACT
365 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 181-199 amino acids (not heteromeric)

Q9HU05 Monofunctional chorismate mutase; EC 5.4.99.5
PFams: CM_2
185 amino acids: PaperBLAST, CDD, Compare to cluster

P9WIB9 Secreted chorismate mutase; *MtCM; CM; EC 5.4.99.5
P9WIB9 Chorismate mutase (EC 5.4.99.5)
PFams: CM_2
199 amino acids: PaperBLAST, CDD, Compare to cluster

A0QU81 Secreted chorismate mutase; CM; EC 5.4.99.5
PFams: CM_2
181 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 181-186 amino acids (not heteromeric)

P42517 Monofunctional chorismate mutase; CM-F; EC 5.4.99.5
PFams: CM_2
181 amino acids: PaperBLAST, CDD, Compare to cluster

Q7CHH5 Secreted chorismate mutase; *MtCM; CM; EC 5.4.99.5
Q7CHH5 Chorismate mutase (EC 5.4.99.5)
PFams: CM_2
186 amino acids: PaperBLAST, CDD, Compare to cluster

Q93LJ4 Monofunctional chorismate mutase; EC 5.4.99.5
PFams: CM_2
181 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 5 373-377 amino acids (not heteromeric)

P43902 prephenate dehydrogenase (EC 1.3.1.12) (from HMM only)
PFams: CM_2, PDH
377 amino acids: PaperBLAST, CDD, Compare to cluster

CHORISMUTPREPHENDEHYDROG-MONOMER fused chorismate mutase/prephenate dehydrogenase (EC 5.4.99.5; EC 1.3.1.12)
PFams: CM_2, PDH
373 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 6 104-105 amino acids (not heteromeric)

P9WIC1 Intracellular chorismate mutase; CM; EC 5.4.99.5
P9WIC1 Chorismate mutase (EC 5.4.99.5)
PFams: CM_2
105 amino acids: PaperBLAST, CDD, Compare to cluster

A0R3N5 Intracellular chorismate mutase; CM; EC 5.4.99.5
PFams: CM_2
104 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 7 275-286 amino acids (not heteromeric)

B6C761 Chorismate mutase (EC 5.4.99.5)
PFams: CM_2
286 amino acids: PaperBLAST, CDD, Compare to cluster

Q3LUE0 Chorismate mutase (EC 5.4.99.5)
PFams: CM_2
275 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 8 591-620 amino acids (not heteromeric)

O30012 prephenate dehydrogenase (EC 1.3.1.12); prephenate dehydratase (EC 4.2.1.51); Chorismate mutase (EC 5.4.99.5)
PFams: PDH, CM_2, PDT, ACT
620 amino acids: PaperBLAST, CDD, Compare to cluster

Q74NC4 prephenate dehydratase (EC 4.2.1.51) (from HMM only)
PFams: PDH, CM_2, PDT, ACT
591 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 9 122-127 amino acids (not heteromeric)

Q84FH6 Chorismate mutase AroH; EC 5.4.99.5
Q84FH6 Chorismate mutase (EC 5.4.99.5)
PFams: CM_1
122 amino acids: PaperBLAST, CDD, Compare to cluster

P19080 Chorismate mutase AroH; CM; EC 5.4.99.5
PFams: CM_1
127 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/4 heteromeric)

A8AAX2 prephenate dehydrogenase (NADP+) (EC 1.3.1.13) (from HMM only)
PFams: CM_2, Rossmann-like, F420_oxidored, NAD_binding_2, PDH
348 amino acids: PaperBLAST, CDD

Q51507 Isochorismate pyruvate lyase; IPL; Chorismate mutase; CM; Salicylate biosynthesis protein; EC 4.2.99.21; EC 5.4.99.5
Q51507 isochorismate lyase (EC 4.2.99.21)
MONOMER-15305 isochorismate pyruvate lyase (EC 4.2.99.21)
PFams: CM_2
101 amino acids: PaperBLAST, CDD

P9WFX1 Salicylate synthase; Chorismate mutase; CM; Isochorismate synthase/isochorismate lyase; Mycobactin synthase protein; EC 5.4.99.5; EC 4.2.99.21; EC 5.4.4.2
PFams: Chorismate_bind
450 amino acids: PaperBLAST, CDD

Q57696 Chorismate mutase; CM; Monofunctional chorismate mutase AroQ(f); EC 5.4.99.5
PFams: CM_2
99 amino acids: PaperBLAST, CDD