Other Characterized Proteins Similar to dctP

Finding the characterized proteins for dctP (2-oxoglutarate TRAP transporter, solute receptor component DctP) in 2-oxoglutarate (alpha-ketoglutarate) catabolism

Or see clustering for step dctP

Or see all steps for 2-oxoglutarate (alpha-ketoglutarate) catabolism

Or cluster curated proteins matching a keyword

Definition of dctP

• Curated sequence 6938088: alpha-ketoglutarate TRAP transporter, solute receptor component
• Curated sequence A3QCW5: C4-dicarboxylate-binding periplasmic protein DctP. dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), solute receptor component
• UniProt sequence I7END8: SubName: Full=C4-dicarboxylate-binding periplasmic protein DctP {ECO:0000313|EMBL:AFO91753.1};
• Ignore hits to Q9KQR9 when looking for 'other' hits (C4-dicarboxylate-binding periplasmic protein DctP)
• Ignore hits to Q9HU18 when looking for 'other' hits (C4-dicarboxylate-binding periplasmic protein DctP)
• Ignore hits to P37735 when looking for 'other' hits (C4-dicarboxylate-binding periplasmic protein DctP. DctP, component of Tripartite dicarboxylate:H+ symporter (substrates include: fumarate, D- and L-malate, succinate, succinamide, orotate, iticonate and mesaconate))
• Comment: Besides the system in Shewanellas, a similar system in Phaeobacter inhibens is important for 2-oxoglutarate utilization: DctP = PGA1_c20680 = I7END8; DctQ = PGA1_c20670 = I7EY26; DctM = PGA1_c20660 = I7DRS6. And for various related dctP-like components, it's not clear if alpha-ketoglutarate is a substrate or not, so they are ignored.

Fetched 3 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 4 other characterized sequences. (Found 6 hits including self hits.)

Removing ignored items reduces this to 1 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for dctP.)

DCTB_BACSU / P96600 C4-dicarboxylate-binding protein DctB from Bacillus subtilis (strain 168)
PFams: DctP
350 amino acids: PaperBLAST, CDD, SwissProt::P96600
40% identical to

Sama_2209 alpha-ketoglutarate TRAP transporter, solute receptor component from Shewanella amazonensis SB2B
PFams: DctP
Heteromeric, 339 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for dctP.)

DCTP_VIBCH / Q9KQR9 C4-dicarboxylate-binding periplasmic protein DctP from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
PFams: DctP
332 amino acids: PaperBLAST, CDD, SwissProt::Q9KQR9
66% identical to

I7END8 C4-dicarboxylate-binding periplasmic protein DctP
333 amino acids: PaperBLAST, CDD

DCTP_PSEAE / Q9HU18 C4-dicarboxylate-binding periplasmic protein DctP from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: DctP
331 amino acids: PaperBLAST, CDD, SwissProt::Q9HU18
58% identical to

Shew_1446 dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), solute receptor component from Shewanella loihica PV-4
DCTP_SHELP / A3QCW5 C4-dicarboxylate-binding periplasmic protein DctP from Shewanella loihica (strain ATCC BAA-1088 / PV-4)
PFams: DctP
Heteromeric, 336 amino acids: PaperBLAST, CDD

DCTP_RHOCA / P37735 C4-dicarboxylate-binding periplasmic protein DctP from Rhodobacter capsulatus (Rhodopseudomonas capsulata)
TC 2.A.56.1.1 / P37735 DctP, component of Tripartite dicarboxylate:H+ symporter (substrates include: fumarate, D- and L-malate, succinate, succinamide, orotate, iticonate and mesaconate) from Rhodobacter capsulatus (Rhodopseudomonas capsulata)
PFams: DctP
Heteromeric, 333 amino acids: PaperBLAST, CDD, SwissProt::P37735
44% identical to

I7END8 C4-dicarboxylate-binding periplasmic protein DctP
333 amino acids: PaperBLAST, CDD