Clusters of Characterized Proteins

Clustering the characterized proteins for kgtP (2-oxoglutarate:H+ symporter KgtP) in 2-oxoglutarate (alpha-ketoglutarate) catabolism

Or see other characterized proteins similar to kgtP

Or see all steps for 2-oxoglutarate (alpha-ketoglutarate) catabolism

Or cluster curated proteins matching a keyword

Definition of kgtP

• Curated sequence P0AEX3: Alpha-ketoglutarate permease. α-Ketoglutarate (oxoglutarate):H+ symporter. α-ketoglutarate:H⁺ symporter. α-ketoglutarate:H⁺ symporter
• Curated sequence AO353_03810: Alpha-ketoglutarate permease, MFS superfamily
• Curated sequence AO356_17790: alpha-ketoglutarate permease (MHS family)
• UniProt sequence D8J257: SubName: Full=Alpha-ketoglutarate permease of the major facilitator superfamily protein {ECO:0000313|EMBL:ADJ64840.1};
• Ignore hits to Q52000 when looking for 'other' hits (Dicarboxylate:H+ symporter)
• Comment: HSERO_RS16820 (D8J257) is similar and is important for 2-oxoglutarate utilization. Q52000 is a dicarboxylate transporter and could be active on 2-oxoglutarate as well, so is ignored.

Fetched 4 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 4 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 432-457 amino acids (not heteromeric)

b2587 α-ketoglutarate:H⁺ symporter from Escherichia coli K-12 substr. MG1655
P0AEX3 α-ketoglutarate:H⁺ symporter from Escherichia coli (strain K12)
KGTP_ECOLI / P0AEX3 Alpha-ketoglutarate permease from Escherichia coli (strain K12)
TC 2.A.1.6.2 / P0AEX3 α-Ketoglutarate (oxoglutarate):H+ symporter from Escherichia coli
PFams: Sugar_tr, MFS_1, MFS_2, Sugar_tr
432 amino acids: PaperBLAST, CDD, Compare to cluster

D8J257 Alpha-ketoglutarate permease of the major facilitator superfamily protein
457 amino acids: PaperBLAST, CDD, Compare to cluster

AO353_03810 Alpha-ketoglutarate permease, MFS superfamily from Pseudomonas fluorescens FW300-N2E3
PFams: Sugar_tr, MFS_1, Sugar_tr
439 amino acids: PaperBLAST, CDD, Compare to cluster

AO356_17790 alpha-ketoglutarate permease (MHS family) from Pseudomonas fluorescens FW300-N2C3
PFams: Sugar_tr, MFS_1, Sugar_tr
439 amino acids: PaperBLAST, CDD, Compare to cluster