Other Characterized Proteins Similar to ligU

Finding the characterized proteins for ligU (4-oxalomesaconate tautomerase) in 4-hydroxybenzoate catabolism

Or see clustering for step ligU

Or see all steps for 4-hydroxybenzoate catabolism

Or cluster curated proteins matching a keyword

Definition of ligU

• Curated proteins or TIGRFams with EC 5.3.2.8
• Curated sequence Q0KJL4: (4E)-oxalomesaconate Delta-isomerase; OMA isomerase; 1,3-allylic isomerase LigU; EC 5.3.3.-
• Comment: This isomerization can occur spontaneously, but the enzyme is probably required for good growth (i.e., fitness data for utilization of 4-vinylphenol or gallic acid). This enzyme is named gllD in MetaCyc. Note that ligU = Q0KJL4 is reported to carry out a different isomerization of 4-oxalomesaconate as part of this pathway. I believe this is just a question of whether to treat the product as the enol form (in UniProt) or the keto form (in MetaCyc).

Fetched 2 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 2 other characterized sequences. (Found 4 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for ligU.)

Q0QLE6 3-methylitaconate Δ-isomerase (EC 5.3.3.6) from Eubacterium barkeri
MII_EUBBA / Q0QLE6 3-methylitaconate isomerase; (R)-3-methylitaconate isomerase; 3-methylitaconate delta-isomerase; EC 5.3.3.6 from Eubacterium barkeri (Clostridium barkeri)
Q0QLE6 methylitaconate DELTA-isomerase (EC 5.3.3.6) from Eubacterium barkeri
PFams: PrpF
380 amino acids: PaperBLAST, CDD, SwissProt::Q0QLE6
41% identical to

LIGU_NOVK1 / Q0KJL4 (4E)-oxalomesaconate Delta-isomerase; OMA isomerase; 1,3-allylic isomerase LigU; EC 5.3.3.- from Novosphingobium sp. (strain KA1) (Sphingomonas sp. (strain KA1))
PFams: PrpF
357 amino acids: PaperBLAST, CDD

A0A0U2X0E4 aconitate-Δ-isomerase 1 (EC 5.3.3.7) from Ustilago maydis
ADI1_USTMD / A0A0U2X0E4 Aconitate-delta-isomerase 1; Itaconic acid/2-hydroxyparaconate biosynthesis cluster protein ADI1; EC 5.-.-.- from Ustilago maydis (Corn smut fungus)
PFams: PrpF
443 amino acids: PaperBLAST, CDD, SwissProt::A0A0U2X0E4
44% identical to

Q88JY0 4-oxalomesaconate tautomerase (EC 5.3.2.8) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
GALD_PSEPK / Q88JY0 4-oxalomesaconate tautomerase; Gallate degradation protein D; EC 5.3.2.8 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
PFams: PrpF
361 amino acids: PaperBLAST, CDD