GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to paaH

Finding the characterized proteins for paaH (3-hydroxyadipyl-CoA dehydrogenase) in 4-hydroxybenzoate catabolism

Or see clustering for step paaH

Or see all steps for 4-hydroxybenzoate catabolism

Or cluster curated proteins matching a keyword

Definition of paaH

Fetched 37 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 18 other characterized sequences. (Found 55 hits including self hits.)

Removing ignored items reduces this to 17 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for paaH.)

KCR1_ARATH / Q8L9C4 Very-long-chain 3-oxoacyl-CoA reductase 1; Beta-ketoacyl reductase 1; AtKCR1; Protein GLOSSY 8; gl8At; EC 1.1.1.330 from Arabidopsis thaliana (Mouse-ear cress)
Q8L9C4 very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) from Arabidopsis thaliana
PFams: adh_short, KR, adh_short_C2
318 amino acids: PaperBLAST, CDD, SwissProt::Q8L9C4
89% identical to

Q84X96 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Brassica napus
PFams: adh_short, KR, adh_short_C2
319 amino acids: PaperBLAST, CDD

Q0VH88 very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) from Gossypium hirsutum
PFams: KR, adh_short, adh_short_C2
320 amino acids: PaperBLAST, CDD, BRENDA::Q0VH88
68% identical to

Q84X96 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Brassica napus
PFams: adh_short, KR, adh_short_C2
319 amino acids: PaperBLAST, CDD

HBD_BACSU / P45856 Probable 3-hydroxybutyryl-CoA dehydrogenase; Beta-hydroxybutyryl-CoA dehydrogenase; BHBD; EC 1.1.1.157 from Bacillus subtilis (strain 168)
GI|881605 3-hydroxybutyryl-CoA dehydrogenase from Bacillus subtilis
PFams: 3HCDH_N, NAD_binding_2, 3HCDH
287 amino acids: PaperBLAST, CDD, SwissProt::P45856
57% identical to

HBD_CLOAB / P52041 3-hydroxybutyryl-CoA dehydrogenase; Beta-hydroxybutyryl-CoA dehydrogenase; BHBD; EC 1.1.1.157 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
P52041 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.35) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
CH_091789 3-hydroxybutyryl-CoA dehydrogenase; EC 1.1.1.157 from Clostridium acetobutylicum
PFams: 3HCDH_N, UDPG_MGDP_dh_N, 3HCDH
282 amino acids: PaperBLAST, CDD

Q0VH87 very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) from Gossypium hirsutum
PFams: adh_short, KR, adh_short_C2
307 amino acids: PaperBLAST, CDD, BRENDA::Q0VH87
55% identical to

Q84X96 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Brassica napus
PFams: adh_short, KR, adh_short_C2
319 amino acids: PaperBLAST, CDD

Q88KS5 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.178) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
PFams: adh_short, KR, adh_short_C2
255 amino acids: PaperBLAST, CDD, metacyc::MONOMER-11802
54% identical to

HCD2_HUMAN / Q99714 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.178 from Homo sapiens (Human)
Q99714 GDP-6-deoxy-D-talose 4-dehydrogenase (EC 1.1.1.135); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (EC 1.1.1.178) from Bos taurus
Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.35) from Homo sapiens
PFams: adh_short, KR, adh_short_C2
261 amino acids: PaperBLAST, CDD

Q6N3H7 6-carboxyhex-2-enoyl-CoA hydratase from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH, 3HCDH
699 amino acids: PaperBLAST, CDD, metacyc::MONOMER-20678
49% identical to

BPHYT_RS13545 3-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.35) from Burkholderia phytofirmans PsJN
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
706 amino acids: PaperBLAST, CDD

KCR2_ARATH / Q9FYL6 Very-long-chain 3-oxoacyl-CoA reductase-like protein At1g24470; Beta-ketoacyl reductase 2; AtKCR2; EC 1.-.-.- from Arabidopsis thaliana (Mouse-ear cress)
PFams: adh_short, KR, adh_short_C2
312 amino acids: PaperBLAST, CDD, SwissProt::Q9FYL6
47% identical to

Q84X96 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Brassica napus
PFams: adh_short, KR, adh_short_C2
319 amino acids: PaperBLAST, CDD

GI|164506977 D-bifunctional protein from Toxoplasma gondii
PFams: adh_short, KR, adh_short_C2, SCP2, SCP2
629 amino acids: PaperBLAST, CDD, CharProtDB::CH_024095
45% identical to

MFEA_DICDI / Q9NKW1 Peroxisomal multifunctional enzyme A; MFE-A; MFE-1; EC 1.1.1.35 from Dictyostelium discoideum (Slime mold)
PFams: adh_short, KR, adh_short_C2, SCP2
441 amino acids: PaperBLAST, CDD

K4JH65 L-seryl-[seryl-carrier protein] dehydrogenase from Streptomyces sp. K01-0509
PFams: 3HCDH_N, NAD_binding_2, 3HCDH
289 amino acids: PaperBLAST, CDD, metacyc::MONOMER-19419
43% identical to

HBD_SYNWW / Q0AVM2 3-hydroxybutyryl-CoA dehydrogenase; EC 1.1.1.35 from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
PFams: 3HCDH_N, 3HCDH
279 amino acids: PaperBLAST, CDD

Q7BQ74 D-glyceryl/L-seryl-[acp] dehydrogenase from Bacillus cereus
PFams: 3HCDH_N, NAD_binding_2, 3HCDH
282 amino acids: PaperBLAST, CDD, metacyc::MONOMER-19432
42% identical to

HBD_CLOAB / P52041 3-hydroxybutyryl-CoA dehydrogenase; Beta-hydroxybutyryl-CoA dehydrogenase; BHBD; EC 1.1.1.157 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
P52041 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.35) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
CH_091789 3-hydroxybutyryl-CoA dehydrogenase; EC 1.1.1.157 from Clostridium acetobutylicum
PFams: 3HCDH_N, UDPG_MGDP_dh_N, 3HCDH
282 amino acids: PaperBLAST, CDD

H0YSD6 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Taeniopygia guttata
PFams: KR, adh_short, adh_short_C2, MaoC_dehydratas, SCP2, Alkyl_sulf_C
735 amino acids: PaperBLAST, CDD, BRENDA::H0YSD6
52% identical to

MFEA_DICDI / Q9NKW1 Peroxisomal multifunctional enzyme A; MFE-A; MFE-1; EC 1.1.1.35 from Dictyostelium discoideum (Slime mold)
PFams: adh_short, KR, adh_short_C2, SCP2
441 amino acids: PaperBLAST, CDD

ECHA_RAT / Q64428 Trifunctional enzyme subunit alpha, mitochondrial; Monolysocardiolipin acyltransferase; TP-alpha; EC 2.3.1.-; EC 4.2.1.17; EC 1.1.1.211 from Rattus norvegicus (Rat)
Q64428 long-chain-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211); acetyl-CoA C-acyltransferase (EC 2.3.1.16) from Rattus norvegicus
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH, 3HCDH
Heteromeric, 763 amino acids: PaperBLAST, CDD, BRENDA::Q64428
41% identical to

b2341 3-hydroxyacyl-CoA dehydrogenase FadJ (EC 1.1.1.35; EC 1.1.1.211; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8) from Escherichia coli K-12 substr. MG1655
FADJ_ECOLI / P77399 Fatty acid oxidation complex subunit alpha; EC 4.2.1.17; EC 5.1.2.3; EC 1.1.1.35 from Escherichia coli (strain K12)
P77399 3-hydroxyacyl-CoA dehydrogenase FadJ (EC 1.1.1.35; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8) from Escherichia coli (strain K12)
RF|NP_416843 fatty acid oxidation complex subunit alpha; EC 1.1.1.35; EC 4.2.1.17; EC 5.1.2.3 from Escherichia coli K12
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH, 3HCDH
Heteromeric, 714 amino acids: PaperBLAST, CDD

ECHA_HUMAN / P40939 Trifunctional enzyme subunit alpha, mitochondrial; 78 kDa gastrin-binding protein; Monolysocardiolipin acyltransferase; TP-alpha; EC 2.3.1.-; EC 4.2.1.17; EC 1.1.1.211 from Homo sapiens (Human)
P40939 long-chain-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211) from Homo sapiens
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH, 3HCDH
Heteromeric, 763 amino acids: PaperBLAST, CDD, BRENDA::P40939
41% identical to

b2341 3-hydroxyacyl-CoA dehydrogenase FadJ (EC 1.1.1.35; EC 1.1.1.211; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8) from Escherichia coli K-12 substr. MG1655
FADJ_ECOLI / P77399 Fatty acid oxidation complex subunit alpha; EC 4.2.1.17; EC 5.1.2.3; EC 1.1.1.35 from Escherichia coli (strain K12)
P77399 3-hydroxyacyl-CoA dehydrogenase FadJ (EC 1.1.1.35; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8) from Escherichia coli (strain K12)
RF|NP_416843 fatty acid oxidation complex subunit alpha; EC 1.1.1.35; EC 4.2.1.17; EC 5.1.2.3 from Escherichia coli K12
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH, 3HCDH
Heteromeric, 714 amino acids: PaperBLAST, CDD

CH_122238 peroxisomal multifunctional beta-oxidation protein from Emericella nidulans
PFams: adh_short, KR, adh_short_C2, adh_short, adh_short_C2, KR, MaoC_dehydratas
883 amino acids: PaperBLAST, CDD, CharProtDB::CH_122238
52% identical to

MFEA_DICDI / Q9NKW1 Peroxisomal multifunctional enzyme A; MFE-A; MFE-1; EC 1.1.1.35 from Dictyostelium discoideum (Slime mold)
PFams: adh_short, KR, adh_short_C2, SCP2
441 amino acids: PaperBLAST, CDD

DHB12_HUMAN / Q53GQ0 Very-long-chain 3-oxoacyl-CoA reductase; 17-beta-hydroxysteroid dehydrogenase 12; 17-beta-HSD 12; 3-ketoacyl-CoA reductase; KAR; Estradiol 17-beta-dehydrogenase 12; Short chain dehydrogenase/reductase family 12C member 1; EC 1.1.1.330; EC 1.1.1.62 from Homo sapiens (Human)
Q53GQ0 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Homo sapiens
Q53GQ0 very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) from Homo sapiens
PFams: adh_short, KR, adh_short_C2
312 amino acids: PaperBLAST, CDD, BRENDA::Q53GQ0
40% identical to

Q84X96 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Brassica napus
PFams: adh_short, KR, adh_short_C2
319 amino acids: PaperBLAST, CDD

CH_124256 multifunctional beta-oxidation protein (Peroxisomal hydratase-dehydrogenase-epimerase); EC 4.2.1.-, 1.1.1.- from Magnaporthe grisea 70-15
PFams: adh_short, KR, adh_short_C2, adh_short, KR, adh_short_C2, MaoC_dehydratas
896 amino acids: PaperBLAST, CDD, CharProtDB::CH_124256
42% identical to

MFEA_DICDI / Q9NKW1 Peroxisomal multifunctional enzyme A; MFE-A; MFE-1; EC 1.1.1.35 from Dictyostelium discoideum (Slime mold)
PFams: adh_short, KR, adh_short_C2, SCP2
441 amino acids: PaperBLAST, CDD

DHB12_MOUSE / O70503 Very-long-chain 3-oxoacyl-CoA reductase; 17-beta-hydroxysteroid dehydrogenase 12; 17-beta-HSD 12; 3-ketoacyl-CoA reductase; KAR; Estradiol 17-beta-dehydrogenase 12; KIK-I; EC 1.1.1.330; EC 1.1.1.62 from Mus musculus (Mouse)
Q0VGQ1 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Mus musculus
PFams: adh_short, KR, adh_short_C2
312 amino acids: PaperBLAST, CDD, BRENDA::Q0VGQ1
41% identical to

Q84X95 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Brassica napus
PFams: adh_short, KR, adh_short_C2
319 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for paaH.)

HP15_1512 Enoyl-CoA hydratase (EC 4.2.1.17) from Marinobacter adhaerens HP15
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
715 amino acids: PaperBLAST, CDD, reanno::Marino:GFF1550
70% identical to

Q9HZJ2 fatty acid oxidation complex α subunit (EC 1.1.1.35; EC 4.2.1.17) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
715 amino acids: PaperBLAST, CDD