Other Characterized Proteins Similar to pcaI

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to pcaI

Finding the characterized proteins for pcaI (3-oxoadipate CoA-transferase subunit A (PcaI)) in 4-hydroxybenzoate catabolism

Or see clustering for step pcaI

Or see all steps for 4-hydroxybenzoate catabolism

Or cluster curated proteins matching a keyword

Definition of pcaI

Curated sequence CH_021928: 3-oxoadipate CoA-transferase subunit A; EC 2.8.3.6. 3-oxoadipate CoA-transferase (subunit 2/2) (EC 2.8.3.6). α subunit of β-ketoadipate succinyl-CoA transferase (EC 2.8.3.6)
Ignore hits to items matching 2.8.3.6 when looking for 'other' hits
Ignore hits to items matching 2.8.3.5 when looking for 'other' hits
Comment: Ignore EC 2.8.3.5, 3-oxoacid CoA-transferase, usually active on shorter substrates but who knows?

Fetched 1 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 16 other characterized sequences. (Found 17 hits including self hits.)

Removing ignored items reduces this to 3 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for pcaI.)

Psest_1078 acetyl-CoA:acetoacetate CoA transferase, A subunit (EC 2.8.3.8) from Pseudomonas stutzeri RCH2
PFams: CoA_trans
Heteromeric, 231 amino acids: PaperBLAST, CDD, reanno::psRCH2:GFF1045
51% identical to

Q01103 α subunit of β-ketoadipate succinyl-CoA transferase (EC 2.8.3.6) from Pseudomonas putida
Q01103 3-oxoadipate CoA-transferase (subunit 2/2) (EC 2.8.3.6) from Pseudomonas putida
GB|AAA25922.1 3-oxoadipate CoA-transferase subunit A; EC 2.8.3.6 from Pseudomonas putida
PFams: CoA_trans
Heteromeric, 231 amino acids: PaperBLAST, CDD

Pf6N2E2_2111 Dehydrocarnitine CoA-transferase and acetoacetate CoA-transferase, subunit A from Pseudomonas fluorescens FW300-N2E2
PFams: CoA_trans
Heteromeric, 232 amino acids: PaperBLAST, CDD, reanno::pseudo6_N2E2:Pf6N2E2_2111
45% identical to

b2221 acetyl-CoA:acetoacetyl-CoA transferase subunit α from Escherichia coli K-12 substr. MG1655
P76458 acetyl-CoA:acetoacetyl-CoA transferase subunit α from Escherichia coli (strain K12)
PFams: CoA_trans
220 amino acids: PaperBLAST, CDD, ecocyc::ATOD-MONOMER
42% identical to

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for pcaI.)

Q63TL3 3-oxoacid CoA-transferase (EC 2.8.3.5) from Burkholderia pseudomallei
PFams: CoA_trans
234 amino acids: PaperBLAST, CDD, BRENDA::Q63TL3
52% identical to

RR42_RS06555 3-oxoacid CoA-transferase (EC 2.8.3.5) from Cupriavidus basilensis 4G11
PFams: CoA_trans
233 amino acids: PaperBLAST, CDD, reanno::Cup4G11:RR42_RS06555
51% identical to

Sama_1357 3-oxoacid CoA-transferase (EC 2.8.3.5) from Shewanella amazonensis SB2B
PFams: CoA_trans
233 amino acids: PaperBLAST, CDD, reanno::SB2B:6937187
49% identical to

P56006 succinyl-CoA:acetoacetate CoA-transferase subunit A (EC 2.8.3.5) from Helicobacter pylori (strain ATCC 700392 / 26695)
SCOA_HELPY / P56006 Succinyl-CoA:3-ketoacid coenzyme A transferase subunit A; Succinyl-CoA:3-oxoacid CoA-transferase; OXCT A; EC 2.8.3.5 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
PFams: CoA_trans
Heteromeric, 232 amino acids: PaperBLAST, CDD, SwissProt::P56006
44% identical to

Q9JJN4 3-oxoacid CoA-transferase (EC 2.8.3.5) from Mus musculus
PFams: CoA_trans, CoA_trans
520 amino acids: PaperBLAST, CDD, BRENDA::Q9JJN4
45% identical to

SCO2B_MOUSE / Q9ESL0 Succinyl-CoA:3-ketoacid coenzyme A transferase 2B, mitochondrial; 3-oxoacid CoA-transferase 2B; Testis-specific succinyl-CoA:3-oxoacid CoA-transferase 2; SCOT-t2; EC 2.8.3.5 from Mus musculus (Mouse)
PFams: CoA_trans, CoA_trans
520 amino acids: PaperBLAST, CDD, SwissProt::Q9ESL0
45% identical to

SCO2A_RAT / Q5XIJ9 Succinyl-CoA:3-ketoacid coenzyme A transferase 2A, mitochondrial; 3-oxoacid CoA-transferase 2A; Testis-specific succinyl-CoA:3-oxoacid CoA-transferase 1; SCOT-t1; EC 2.8.3.5 from Rattus norvegicus (Rat)
PFams: CoA_trans, CoA_trans
520 amino acids: PaperBLAST, CDD, SwissProt::Q5XIJ9
44% identical to

P55809 succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial (EC 2.8.3.5) from Homo sapiens
SCOT1_HUMAN / P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; EC 2.8.3.5 from Homo sapiens (Human)
P55809 3-oxoacid CoA-transferase (EC 2.8.3.5) from Homo sapiens
PFams: CoA_trans, CoA_trans
520 amino acids: PaperBLAST, CDD, BRENDA::P55809
42% identical to

SCOT2_HUMAN / Q9BYC2 Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial; 3-oxoacid CoA-transferase 2A; Testis-specific succinyl-CoA:3-oxoacid CoA-transferase; SCOT-t; EC 2.8.3.5 from Homo sapiens (Human)
Q9BYC2 3-oxoacid CoA-transferase (EC 2.8.3.5) from Homo sapiens
PFams: CoA_trans, CoA_trans
517 amino acids: PaperBLAST, CDD, SwissProt::Q9BYC2
42% identical to

SCOT1_PIG / Q29551 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; EC 2.8.3.5 from Sus scrofa (Pig)
Q29551 3-oxoacid CoA-transferase (EC 2.8.3.5) from Sus scrofa
PFams: CoA_trans, CoA_trans
520 amino acids: PaperBLAST, CDD, SwissProt::Q29551
41% identical to

Q9D0K2 3-oxoacid CoA-transferase (EC 2.8.3.5) from Mus musculus
PFams: CoA_trans, CoA_trans
520 amino acids: PaperBLAST, CDD, BRENDA::Q9D0K2
40% identical to

SCOT1_RAT / B2GV06 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; EC 2.8.3.5 from Rattus norvegicus (Rat)
B2GV06 3-oxoacid CoA-transferase (EC 2.8.3.5) from Rattus norvegicus
PFams: CoA_trans, CoA_trans
520 amino acids: PaperBLAST, CDD, BRENDA::B2GV06
40% identical to

SCOT_DROME / Q9W058 Succinyl-CoA:3-ketoacid-coenzyme A transferase, mitochondrial; 3-oxoacid CoA-transferase; EC 2.8.3.5 from Drosophila melanogaster (Fruit fly)
Q9W058 3-oxoacid CoA-transferase (EC 2.8.3.5) from Drosophila melanogaster
PFams: CoA_trans, CoA_trans
516 amino acids: PaperBLAST, CDD, SwissProt::Q9W058
40% identical to