Other Characterized Proteins Similar to cycA

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to cycA

Finding the characterized proteins for cycA (D-serine:H+ symporter CycA) in D-serine catabolism

Or see clustering for step cycA

Or see all steps for D-serine catabolism

Or cluster curated proteins matching a keyword

Definition of cycA

Curated sequence A0A0H2VDI7: D-serine/D-alanine/glycine transporter
Curated sequence P0AAE0: D-serine/D-alanine/glycine transporter. D-Serine/D-alanine/glycine/D-cycloserine:H+ symporter. D-serine/alanine/glycine/:H⁺symporter. D-serine/alanine/glycine/:H⁺symporter
Curated sequence F2HQ24: Serine transporter, SerP2 or YdgB, of 459 aas and 12 TMSs (Trip et al. 2013). Transports L-alanine (Km = 20 μM), D-alanine (Km = 38 μM), L-serine, D-serine (Km = 356 μM) and glycine (Noens and Lolkema 2015). The encoding gene is adjacent to the one encoding SerP1 (TC# 2.A.3.1.21)
Curated sequence M1IW84: D-serine/L-alanine/D-alanine/glycine/D-cycloserine uptake porter of 556 aas, CycA
Curated sequence A2RI86: DL-alanine permease SerP2

Fetched 5 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 9 other characterized sequences. (Found 14 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for cycA.)

SERP1_LACLM / A2RI87 Serine permease SerP1 from Lactococcus lactis subsp. cremoris (strain MG1363)
PFams: AA_permease, AA_permease_2
459 amino acids: PaperBLAST, CDD, SwissProt::A2RI87
62% identical to

TC 2.A.3.1.20 / F2HQ24 Serine transporter, SerP2 or YdgB, of 459 aas and 12 TMSs (Trip et al. 2013). Transports L-alanine (Km = 20 μM), D-alanine (Km = 38 μM), L-serine, D-serine (Km = 356 μM) and glycine (Noens and Lolkema 2015). The encoding gene is adjacent to the one encoding SerP1 (TC# 2.A.3.1.21) from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease, AA_permease_2
457 amino acids: PaperBLAST, CDD

TC 2.A.3.1.21 / F2HQ25 Serine uptake transporter, SerP1, of 259 aas and 12 TMSs (Trip et al. 2013). L-serine is the highest affinity substrate (Km = 18 μM), but SerP1 also transports L-threonine and L-cysteine (Km values = 20 - 40 μM) from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease, AA_permease_2
459 amino acids: PaperBLAST, CDD, TCDB::F2HQ25
62% identical to

SERP2_LACLM / A2RI86 DL-alanine permease SerP2 from Lactococcus lactis subsp. cremoris (strain MG1363)
PFams: AA_permease, AA_permease_2
460 amino acids: PaperBLAST, CDD

TC 2.A.3.1.6 / P37460 Proline-specific permease (ProY) from Salmonella typhimurium
PFams: AA_permease_2, Spore_permease, AA_permease
456 amino acids: PaperBLAST, CDD, TCDB::P37460
42% identical to

CYCA_ECOL6 / A0A0H2VDI7 D-serine/D-alanine/glycine transporter from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
PFams: AA_permease, AA_permease_2
470 amino acids: PaperBLAST, CDD

AO356_17670 L-alanine and D-alanine permease from Pseudomonas fluorescens FW300-N2C3
PFams: AA_permease, AA_permease_2
473 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_17670
43% identical to

b4208 D-serine/alanine/glycine/:H⁺symporter from Escherichia coli K-12 substr. MG1655
P0AAE0 D-serine/alanine/glycine/:H⁺symporter from Escherichia coli (strain K12)
CYCA_ECOLI / P0AAE0 D-serine/D-alanine/glycine transporter from Escherichia coli (strain K12)
TC 2.A.3.1.7 / P0AAE0 D-Serine/D-alanine/glycine/D-cycloserine:H+ symporter from Escherichia coli
PFams: AA_permease, AA_permease_2
470 amino acids: PaperBLAST, CDD

AO353_16120 D-alanine and L-alanine transporter from Pseudomonas fluorescens FW300-N2E3
PFams: AA_permease, AA_permease_2
472 amino acids: PaperBLAST, CDD, reanno::pseudo3_N2E3:AO353_16120
43% identical to

b0112 aromatic amino acid:H⁺ symporter AroP from Escherichia coli K-12 substr. MG1655
P15993 aromatic amino acid:H⁺ symporter AroP from Escherichia coli (strain K12)
TC 2.A.3.1.3 / P15993 Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan from Escherichia coli
PFams: AA_permease, AA_permease_2
457 amino acids: PaperBLAST, CDD, TCDB::P15993
40% identical to

PS417_05405 L-alanine and D-alanine permease from Pseudomonas simiae WCS417
PFams: AA_permease, AA_permease_2
472 amino acids: PaperBLAST, CDD, reanno::WCS417:GFF1065
42% identical to

AO353_12275 histidine permease from Pseudomonas fluorescens FW300-N2E3
PFams: AA_permease, AA_permease_2
468 amino acids: PaperBLAST, CDD, reanno::pseudo3_N2E3:AO353_12275
40% identical to

TC 2.A.3.1.23 / P0AAE2 ProY of 457 aas and 12 TMSs from Escherichia coli (strain K12)
PFams: AA_permease_2, Spore_permease, AA_permease
457 amino acids: PaperBLAST, CDD, TCDB::P0AAE2
41% identical to