Other Characterized Proteins Similar to lctP

Finding the characterized proteins for lctP (L-lactate:H+ symporter LctP or LidP) in L-lactate catabolism

Or see clustering for step lctP

Or see all steps for L-lactate catabolism

Or cluster curated proteins matching a keyword

Definition of lctP

• Curated sequence P33231: L-lactate permease. Lactate permease, LctP or LidP (substrates: L-lactate, D-lactate and glycolate). lactate/glycolate:H⁺ symporter LldP. lactate/glycolate:H⁺ symporter LldP. (R)-lactate / (S)-lactate / glycolate:H+ symporter LldP
• Curated sequence P71067: L-lactate permease. L-lactate permease
• Curated sequence AO356_07550: L-lactate and D-lactate permease (lctP family)
• Curated sequence Q46839: Glycolate permease, GlcA or YghK (substrates: L-lactate, D-lactate and glycolate). glycolate/lactate:H⁺ symporter GlcA. glycolate/lactate:H⁺ symporter GlcA
• Ignore hits to GFF4712 when looking for 'other' hits (D-lactate transporter (lctP family))
• UniProt sequence Q8EGS2: RecName: Full=L-lactate permease {ECO:0000256|RuleBase:RU365092};
• UniProt sequence L0GFN1: RecName: Full=L-lactate permease {ECO:0000256|RuleBase:RU365092};
• Curated sequence P71067: L-lactate permease. L-lactate permease
• Comment: E. coli GlcA (Q46839) is similar to LctP and is reported to transport both L- and D-lactate. PS417_24105 (GFF4172) is important only for D-lactate utilization but is closely related to AO356_07550 and could be an L-lactate transporter as well. SO_1522 (Q8EGS2) and Psest_0955 (L0GFN1) probably transport both isomers. Bacillus subtilis LutP (P71067) is an L-lactate transporter.

Fetched 6 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 1 other characterized sequences. (Found 5 hits including self hits.)

Removing ignored items reduces this to 0 close sequences.

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for lctP.)

PS417_24105 D-lactate transporter (lctP family) from Pseudomonas simiae WCS417
PFams: Lactate_perm
564 amino acids: PaperBLAST, CDD, reanno::WCS417:GFF4712
95% identical to

AO356_07550 L-lactate and D-lactate permease (lctP family) from Pseudomonas fluorescens FW300-N2C3
PFams: Lactate_perm
564 amino acids: PaperBLAST, CDD