Other Characterized Proteins Similar to gyaR

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to gyaR

Finding the characterized proteins for gyaR (glyoxylate reductase) in L-arabinose catabolism

Or see clustering for step gyaR

Or see all steps for L-arabinose catabolism

Or cluster curated proteins matching a keyword

Definition of gyaR

Curated proteins or TIGRFams with EC 1.1.1.26
Ignore hits to items matching 1.1.1.79 when looking for 'other' hits
Comment: The NADP based glyoxylate reductase (EC 1.1.1.79) is probably biased in the wrong direction for glycolate oxidation, so do not include, but ignore homology to it.

Fetched 6 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 21 other characterized sequences. (Found 27 hits including self hits.)

Removing ignored items reduces this to 13 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for gyaR.)

B1Q3F6 NAD-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.24) from Solanum lycopersicum
PFams: NAD_binding_2, ApbA, F420_oxidored, NAD_binding_11
287 amino acids: PaperBLAST, CDD, metacyc::MONOMER-15565
81% identical to

Q9LSV0 succinate semialdehyde reductase (NADPH) from Arabidopsis thaliana
GLYR1_ARATH / Q9LSV0 Glyoxylate/succinic semialdehyde reductase 1; AtGLYR1; AtGR1; SSA reductase 1; Gamma-hydroxybutyrate dehydrogenase; AtGHBDH; EC 1.1.1.79; EC 1.1.1.n11 from Arabidopsis thaliana (Mouse-ear cress)
Q9LSV0 glyoxylate reductase (EC 1.1.1.26); 4-hydroxybutyrate dehydrogenase (EC 1.1.1.61); glyoxylate reductase (NADP+) (EC 1.1.1.79) from Arabidopsis thaliana
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
289 amino acids: PaperBLAST, CDD

A0A1I9LPQ6 hydroxypyruvate reductase (EC 1.1.1.81) from Arabidopsis thaliana
PFams: NAD_binding_2, F420_oxidored, NAD_binding_11
207 amino acids: PaperBLAST, CDD, BRENDA::A0A1I9LPQ6
100% identical to

GLYR1_HUMAN / Q49A26 Putative oxidoreductase GLYR1; 3-hydroxyisobutyrate dehydrogenase-like protein; Cytokine-like nuclear factor N-PAC; Glyoxylate reductase 1 homolog; Nuclear protein NP60; Nuclear protein of 60 kDa; Nucleosome-destabilizing factor; hNDF; EC 1.-.-.- from Homo sapiens (Human)
PFams: PWWP, F420_oxidored, NAD_binding_2, NAD_binding_11
553 amino acids: PaperBLAST, CDD, SwissProt::Q49A26
49% identical to

GLYR1_MOUSE / Q922P9 Putative oxidoreductase GLYR1; Glyoxylate reductase 1 homolog; Nuclear protein NP60; EC 1.-.-.- from Mus musculus (Mouse)
PFams: PWWP, F420_oxidored, NAD_binding_2, NAD_binding_11
546 amino acids: PaperBLAST, CDD, SwissProt::Q922P9
48% identical to

BPHYT_RS11290 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) from Burkholderia phytofirmans PsJN
PFams: 2-Hacid_dh, 2-Hacid_dh_C, NAD_binding_2
321 amino acids: PaperBLAST, CDD, reanno::BFirm:BPHYT_RS11290
45% identical to

GYAR_THELN / Q9C4M5 Glyoxylate reductase; EC 1.1.1.26 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C)
Q9C4M5 glyoxylate reductase (EC 1.1.1.26) from Thermococcus litoralis
PFams: 2-Hacid_dh, 2-Hacid_dh_C, IlvN, NAD_binding_2
331 amino acids: PaperBLAST, CDD

A0A1D8RK43 gluconate 2-dehydrogenase (EC 1.1.1.215) from Aspergillus niger
PFams: 2-Hacid_dh, 2-Hacid_dh_C
331 amino acids: PaperBLAST, CDD, BRENDA::A0A1D8RK43
44% identical to

P53839 glyoxylate reductase 1 (EC 1.1.1.26) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
GOR1_YEAST / P53839 Glyoxylate reductase 1; EC 1.1.1.26 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: 2-Hacid_dh, 2-Hacid_dh_C
350 amino acids: PaperBLAST, CDD

Q2U0N3 D-2-hydroxyacid dehydrogenase (NADP⁺) (EC 1.1.1.272) from Aspergillus oryzae (strain ATCC 42149 / RIB 40)
PFams: 2-Hacid_dh, 2-Hacid_dh_C
329 amino acids: PaperBLAST, CDD, metacyc::MONOMER-19754
44% identical to

GLYR1_DROME / Q8T079 Putative oxidoreductase GLYR1 homolog; Glyoxylate reductase 1 homolog; Nuclear protein NP60 homolog; Nucleosome-destabilizing factor; EC 1.-.-.- from Drosophila melanogaster (Fruit fly)
PFams: PWWP, Shikimate_DH, F420_oxidored, NAD_binding_2, NAD_binding_11
602 amino acids: PaperBLAST, CDD, SwissProt::Q8T079
40% identical to

HPR_THEMA / Q9X1C1 Hydroxypyruvate reductase; HPR; EC 1.1.1.81 from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
PFams: 2-Hacid_dh, 2-Hacid_dh_C, NAD_binding_2
306 amino acids: PaperBLAST, CDD, SwissProt::Q9X1C1
42% identical to

Q65CJ7 hydroxyphenylpyruvate reductase (EC 1.1.1.237) from Plectranthus scutellarioides
HPPR_PLESU / Q65CJ7 Hydroxyphenylpyruvate reductase; HPPR; EC 1.1.1.237 from Plectranthus scutellarioides (Coleus) (Solenostemon scutellarioides)
Q65CJ7 hydroxyphenylpyruvate reductase (EC 1.1.1.237) from Plectranthus scutellarioides
PFams: 2-Hacid_dh, 2-Hacid_dh_C
313 amino acids: PaperBLAST, CDD, SwissProt::Q65CJ7
41% identical to

P36234 hydroxypyruvate reductase subunit (EC 1.1.1.81) from Hyphomicrobium methylovorum
PFams: 2-Hacid_dh, 2-Hacid_dh_C, NAD_binding_2
322 amino acids: PaperBLAST, CDD, metacyc::MONOMER-4245
40% identical to

A0A0A7RFJ3 hydroxyphenylpyruvate reductase (EC 1.1.1.237) from Salvia miltiorrhiza
PFams: 2-Hacid_dh, 2-Hacid_dh_C
313 amino acids: PaperBLAST, CDD, BRENDA::A0A0A7RFJ3
41% identical to

2KGR_GLUOX / Q5FTU6 2-ketogluconate reductase; 2KGR; Gluconate 2-dehydrogenase; EC 1.1.1.215 from Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans)
Q5FTU6 gluconate 2-dehydrogenase (EC 1.1.1.215) from Gluconobacter oxydans
PFams: 2-Hacid_dh, 2-Hacid_dh_C
310 amino acids: PaperBLAST, CDD, BRENDA::Q5FTU6
40% identical to

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for gyaR.)

Q8U3Y2 glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Pyrococcus furiosus
PFams: 2-Hacid_dh, 2-Hacid_dh_C, IlvN, F420_oxidored, NAD_binding_2
336 amino acids: PaperBLAST, CDD, BRENDA::Q8U3Y2
71% identical to

F8AEA4 glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Pyrococcus yayanosii
PFams: 2-Hacid_dh, 2-Hacid_dh_C, IlvN, F420_oxidored, NAD_binding_2
333 amino acids: PaperBLAST, CDD, BRENDA::F8AEA4
70% identical to

GLYR2_ARATH / F4I907 Glyoxylate/succinic semialdehyde reductase 2, chloroplastic; AtGLYR2; AtGR2; SSA reductase 2; EC 1.1.1.79; EC 1.1.1.n11 from Arabidopsis thaliana (Mouse-ear cress)
F4I907 glyoxylate reductase (NADP+) (EC 1.1.1.79) from Arabidopsis thaliana
PFams: NAD_binding_2, ApbA, NAD_binding_11
358 amino acids: PaperBLAST, CDD, BRENDA::F4I907
58% identical to

b3553 glyoxylate reductase (EC 1.1.1.79; EC 1.1.1.215) from Escherichia coli K-12 substr. MG1655
P37666 glyoxylate reductase (EC 1.1.1.79; EC 1.1.1.215) from Escherichia coli (strain K12)
GHRB_ECOLI / P37666 Glyoxylate/hydroxypyruvate reductase B; 2-ketoaldonate reductase; 2-ketogluconate reductase; 2KR; EC 1.1.1.79; EC 1.1.1.81; EC 1.1.1.215 from Escherichia coli (strain K12)
GB|AAC76577.2 glyoxylate/hydroxypyruvate reductase B; EC 1.1.1.215; EC 1.1.1.79; EC 1.1.1.81 from Escherichia coli K12
PFams: 2-Hacid_dh, 2-Hacid_dh_C
324 amino acids: PaperBLAST, CDD, CharProtDB::CH_012867
43% identical to

A0A0H3U0Y7 glyoxylate reductase (NADP+) (EC 1.1.1.79) from Paecilomyces sp. 'thermophila'
PFams: 2-Hacid_dh, 2-Hacid_dh_C
330 amino acids: PaperBLAST, CDD, BRENDA::A0A0H3U0Y7
46% identical to

Q9CA90 glyoxylate reductase (NADP⁺) (EC 1.1.1.79; EC 1.1.1.81) from Arabidopsis thaliana
HPR2_ARATH / Q9CA90 Glyoxylate/hydroxypyruvate reductase A HPR2; NAD(P)H-dependent hydroxypyruvate reductase 2; AtHPR2; HPR 2; EC 1.1.1.79; EC 1.1.1.81 from Arabidopsis thaliana (Mouse-ear cress)
Q9CA90 glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Arabidopsis thaliana
PFams: 2-Hacid_dh, 2-Hacid_dh_C
313 amino acids: PaperBLAST, CDD, BRENDA::Q9CA90
43% identical to

Q9LE33 glyoxylate reductase (NADP⁺) (EC 1.1.1.79; EC 1.1.1.81) from Arabidopsis thaliana
HPR3_ARATH / Q9LE33 Glyoxylate/hydroxypyruvate reductase HPR3; NAD(P)H-dependent hydroxypyruvate reductase 3; AtHPR3; HPR 3; EC 1.1.1.79; EC 1.1.1.81 from Arabidopsis thaliana (Mouse-ear cress)
Q9LE33 hydroxypyruvate reductase (EC 1.1.1.81) from Arabidopsis thaliana
PFams: 2-Hacid_dh, 2-Hacid_dh_C
323 amino acids: PaperBLAST, CDD, BRENDA::Q9LE33
40% identical to

A0A178WMD4 glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Arabidopsis thaliana
PFams: 2-Hacid_dh, 2-Hacid_dh_C
323 amino acids: PaperBLAST, CDD, BRENDA::A0A178WMD4
40% identical to