Other Characterized Proteins Similar to artJ
Finding the characterized proteins for artJ (L-arginine ABC transporter, periplasmic substrate-binding component ArtJ/HisJ/ArtI/AotJ/ArgT) in L-arginine catabolism
Or see clustering for step artJ
Or see all steps for L-arginine catabolism
Or cluster curated proteins matching a keyword
Definition of artJ
- Curated sequence AO353_03055: ABC transporter for L-Arginine and L-Citrulline, periplasmic substrate-binding component
- Curated sequence CH_002541: arginine ABC transporter, periplasmic arginine-binding protein ArtJ. ABC transporter arginine-binding protein 1. ArtJ aka B0860, component of Arginine porter. L-arginine ABC transporter periplasmic binding protein (EC 7.4.2.1). L-arginine ABC transporter periplasmic binding protein (EC 7.4.2.1)
- Curated sequence CH_003045: lysine/arginine/ornithine ABC transporter, periplasmic lysine/arginine/ornithine-binding protein ArgT. Lysine/arginine/ornithine-binding periplasmic protein; LAO-binding protein
- Curated sequence CH_014295: histidine ABC transporter, periplasmic histidine-binding protein HisJ. Histidine-binding periplasmic protein, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential. histidine ABC transporter periplasmic binding protein (EC 7.4.2.1)
- Curated sequence P30859: Putative ABC transporter arginine-binding protein 2. ArtI aka B0863, component of Arginine porter
- Curated sequence O50181: AotJ aka PA0888, component of Arginine/ornithine (but not lysine) porter
- Curated sequence P09551: ArgT aka B2310, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential. lysine/arginine/ornithine ABC transporter periplasmic binding protein (EC 7.4.2.1)
- Curated sequence Q9HU31: Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter periplasmic binding protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR
- Curated sequence BPHYT_RS07735: ABC transporter for L-Arginine, periplasmic substrate-binding component
- Curated sequence GFF4245: ABC transporter for L-Arginine, substrate-binding component
- Curated sequence Pf1N1B4_3431: ABC transporter for L-Arginine and L-Citrulline, periplasmic substrate-binding component
- Curated sequence AO356_18700: L-Arginine ABC transporter, periplasmic substrate-binding component
- Curated sequence Pf6N2E2_5660: L-Arginine ABC transporter, periplasmic substrate-binding component
- Ignore hits to CH_018185 when looking for 'other' hits (histidine ABC transporter, periplasmic histidine-binding protein HisJ. Histidine-binding periplasmic protein; HBP)
- Ignore hits to AO356_09900 when looking for 'other' hits (ABC transporter for L-Lysine, periplasmic substrate-binding component)
- Ignore hits to Pf6N2E2_2958 when looking for 'other' hits (ABC transporter for L-Lysine, periplasmic substrate-binding component)
- Ignore hits to AO356_05495 when looking for 'other' hits (ABC transporter for L-Lysine, periplasmic substrate-binding component)
- UniProt sequence E4PNW5: SubName: Full=Extracellular solute-binding protein, family 3 {ECO:0000313|EMBL:ADP98795.1};
- Comment: Many ABC transporters are known for arginine, including E. coli artJQMP (which is specific for arginine) and E. coli hisQPM-argT (also transports lysine, ornithine) These systems are generally homologous, but the two permease components also similar to each other. To simplify the analysis, these were clustered at 40% identity instead of the usual 30% identity. Distantly related proteins from Chlamydia (ARTJ_CHLTR, ARTJ_CHLPN) are annotated as artJ but are not actually characterized, and the other components of this system seem to be absent. So Chlamydial "artJ" were not included. Ignore hisJ (CH_018185) from Salmonella and the P. fluorescens lysine transporter (AO356_09900), which has a subtle defect on arginine and may well transport it, and close homologs in other Pseudomonas. In Marinobacter adhaerens, the SBP (HP15_3031, E4PNW5) is somewhat diverged, but fitness data confirms it is involved.
Fetched 14 sequences
Running ublast to find other characterized proteins with 40% identity and 70% coverage
Found hits to 4 other characterized sequences. (Found 17 hits including self hits.)
Removing ignored items reduces this to 0 close sequences.
Close but ignored sequences
(Sequences that are similar to these will still be high-confidence candidates for artJ.)
HISJ_SALTY / P02910 Histidine-binding periplasmic protein; HBP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
GB|AAV76512.1 histidine ABC transporter, periplasmic histidine-binding protein HisJ from Salmonella enterica subsp. enterica serovar Typhimurium
PFams: SBP_bac_3
260 amino acids: PaperBLAST, CDD, CharProtDB::CH_018185
98% identical to
b2309 histidine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655
TC 3.A.1.3.29 / P0AEU0 Histidine-binding periplasmic protein, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (strain K12)
GB|AAC75369.1 histidine ABC transporter, periplasmic histidine-binding protein HisJ from Escherichia coli
PFams: SBP_bac_3
Heteromeric, 260 amino acids: PaperBLAST, CDD
AO356_09900 ABC transporter for L-Lysine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
PFams: SBP_bac_3, Lig_chan-Glu_bd
Heteromeric, 251 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_09900
77% identical to
TC 3.A.1.3.23 / Q9HU31 Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter periplasmic binding protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
PFams: SBP_bac_3, Lig_chan-Glu_bd
Heteromeric, 250 amino acids: PaperBLAST, CDD
Pf6N2E2_2958 ABC transporter for L-Lysine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
PFams: SBP_bac_3, NMT1
Heteromeric, 260 amino acids: PaperBLAST, CDD, reanno::pseudo6_N2E2:Pf6N2E2_2958
51% identical to
BPHYT_RS07735 ABC transporter for L-Arginine, periplasmic substrate-binding component from Burkholderia phytofirmans PsJN
PFams: SBP_bac_3, NMT1
Heteromeric, 264 amino acids: PaperBLAST, CDD
AO356_05495 ABC transporter for L-Lysine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
PFams: SBP_bac_3, NMT1
Heteromeric, 260 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_05495
50% identical to
BPHYT_RS07735 ABC transporter for L-Arginine, periplasmic substrate-binding component from Burkholderia phytofirmans PsJN
PFams: SBP_bac_3, NMT1
Heteromeric, 264 amino acids: PaperBLAST, CDD