Other Characterized Proteins Similar to celEIIA

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to celEIIA

Finding the characterized proteins for celEIIA (cellobiose PTS system, EII-A component) in D-cellobiose catabolism

Or see clustering for step celEIIA

Or see all steps for D-cellobiose catabolism

Or cluster curated proteins matching a keyword

Definition of celEIIA

Curated sequence P69791: PTS system N,N'-diacetylchitobiose-specific EIIA component; EIIA-Chb; EIII-Chb; IIIcel; N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIA component. PTCA aka ChbA aka CELC aka B1736, component of N,N'-diacetylchitobiose (Chb) porter. N,N'-diacetylchitobiose-specific PTS enzyme IIA component (EC 2.7.1.196). N,N'-diacetylchitobiose-specific PTS enzyme IIA component (EC 2.7.1.196)
Curated sequence Q9CIE9: PTS system cellobiose-specific EIIA component. PtcA, component of The cellobiose-specific (PtcA-PtcB-CelB) porter (Kowalczyk et al., 2008 )
UniProt sequence A0A0H2UNC0: SubName: Full=PTS system, IIA component {ECO:0000313|EMBL:AAK74485.1};
Ignore hits to A2RIE7 when looking for 'other' hits (PTS system galactose-specific EIIA component)
Ignore hits to C4X746 when looking for 'other' hits (PEP-dependent phosphotransferase enzyme III, component of N,N'-diacetylchitobiose (cellobiose) PTS permease, CelABC (IIABC))
Comment: E. coli also has chbABC (separate EII-A, EII-B and EII-C components), and Lactococcus lactis has a similar system (ptcA-ptcB-celB). Separate EIIABC proteins are also known in Streptococcus pneumoniae, see PMC3302838. (SP0308 = celC = EIIA = A0A0H2UNC0; Sp0305 = celB = EIIB = A0A0H2UNC2; SP0310 = celD = EIIC = A0A0H2UNC6.) Ignore a close homolog from L. lactis cremoris (annotated as galactose-specific) and a systems from Klebsiella pneumoniae and Serratia marcescens that may transport cellobiose.

Fetched 3 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 9 other characterized sequences. (Found 11 hits including self hits.)

Removing ignored items reduces this to 7 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for celEIIA.)

TC 4.A.3.2.6 / Q9KSH3 VC_1283 aka IIA, component of Glucosamine β(1→4) glucosamine (GlcN)2 (glucosamine dimer) transporter, VC1281-1283 (IIB; IIC; IIA, respectively) from Vibrio cholerae
PFams: PTS_IIA
Heteromeric, 111 amino acids: PaperBLAST, CDD, TCDB::Q9KSH3
52% identical to

b1736 N,N'-diacetylchitobiose-specific PTS enzyme IIA component (EC 2.7.1.196) from Escherichia coli K-12 substr. MG1655
P69791 N,N'-diacetylchitobiose-specific PTS enzyme IIA component (EC 2.7.1.196) from Escherichia coli (strain K12)
PTQA_ECOLI / P69791 PTS system N,N'-diacetylchitobiose-specific EIIA component; EIIA-Chb; EIII-Chb; IIIcel; N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIA component from Escherichia coli (strain K12)
TC 4.A.3.2.1 / P69791 PTCA aka ChbA aka CELC aka B1736, component of N,N'-diacetylchitobiose (Chb) porter from Escherichia coli
PFams: PTS_IIA
Heteromeric, 116 amino acids: PaperBLAST, CDD

TC 4.A.3.2.8 / Q72XQ1 PTS system, cellobiose-specific IIA component, component of N-, N'-diacetylchitobiose PTS permease, IIABCChb from Bacillus cereus (strain ATCC 10987)
PFams: PTS_IIA
Heteromeric, 105 amino acids: PaperBLAST, CDD, TCDB::Q72XQ1
54% identical to

PTCA_LACLA / Q9CIE9 PTS system cellobiose-specific EIIA component from Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
TC 4.A.3.2.4 / Q9CIE9 PtcA, component of The cellobiose-specific (PtcA-PtcB-CelB) porter (Kowalczyk et al., 2008 ) from Lactococcus lactis subsp. lactis (Streptococcus lactis)
PFams: PTS_IIA
Heteromeric, 116 amino acids: PaperBLAST, CDD

TC 4.A.3.2.2 / P46319 PTCA aka LicA aka CELC, component of Lichenan oligosaccharide (Lic) porter from Bacillus subtilis
PFams: PTS_IIA
Heteromeric, 110 amino acids: PaperBLAST, CDD, TCDB::P46319
44% identical to

A0A0H2UNC0 PTS system, IIA component
104 amino acids: PaperBLAST, CDD

PTLA_STAAU / P0A0D6 PTS system lactose-specific EIIA component; EIIA-Lac; EIII-Lac; Lactose-specific phosphotransferase enzyme IIA component from Staphylococcus aureus
TC 4.A.3.1.1 / P0A0D6 PtlA aka LACF, component of Lactose (Lac) porter, LacEF from Staphylococcus aureus
PFams: PTS_IIA
Heteromeric, 103 amino acids: PaperBLAST, CDD, SwissProt::P0A0D6
43% identical to

A0A0H2UNC0 PTS system, IIA component
104 amino acids: PaperBLAST, CDD

Q45402 protein-Npi-phosphohistidine-cellobiose phosphotransferase (EC 2.7.1.205) from Geobacillus stearothermophilus
PFams: PTS_IIA
108 amino acids: PaperBLAST, CDD, BRENDA::Q45402
48% identical to

TC 4.A.3.2.9 / U5MLJ3 PTS lactose transporter subunit IIA, component of PTS-type lactose transporter, IIC-IIB-IIA from Klebsiella pneumoniae CG43
PFams: PTS_IIA
Heteromeric, 105 amino acids: PaperBLAST, CDD, TCDB::U5MLJ3
48% identical to

PTLA_LACLL / P23532 PTS system lactose-specific EIIA component; EIIA-Lac; EIII-Lac; Lactose-specific phosphotransferase enzyme IIA component from Lactococcus lactis subsp. lactis (Streptococcus lactis)
PFams: PTS_IIA
105 amino acids: PaperBLAST, CDD, SwissProt::P23532
41% identical to

A0A0H2UNC0 PTS system, IIA component
104 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for celEIIA.)

PTCA_LACLM / A2RIE7 PTS system galactose-specific EIIA component from Lactococcus lactis subsp. cremoris (strain MG1363)
PFams: PTS_IIA
116 amino acids: PaperBLAST, CDD, SwissProt::A2RIE7
97% identical to

TC 4.A.3.2.7 / C4X746 PEP-dependent phosphotransferase enzyme III, component of N,N'-diacetylchitobiose (cellobiose) PTS permease, CelABC (IIABC) from Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
PFams: PTS_IIA
Heteromeric, 115 amino acids: PaperBLAST, CDD, TCDB::C4X746
81% identical to