Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for acn (aconitase) in citrate catabolism

Or see other characterized proteins similar to acn

Or see all steps for citrate catabolism

Or cluster curated proteins matching a keyword

Definition of acn

Curated proteins or TIGRFams with EC 4.2.1.3
Ignore hits to items matching aconitase when looking for 'other' hits
Comment: Some similar sequences are annotated as aconitase but without the EC number

Fetched 52 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 52 of these sequences

Found 5 clusters of similar sequences. Download as table or as draft rules or view by cluster

Achromobacter denitrificans

A0A090AMG4 aconitate hydratase (EC 4.2.1.3) from Achromobacter denitrificans
PFams: Aconitase, Aconitase_C
901 amino acids: PaperBLAST, CDD (Cluster 1)

Arabidopsis thaliana

Q42560 aconitase from Arabidopsis thaliana
ACO1_ARATH / Q42560 Aconitate hydratase 1; Aconitase 1; Citrate hydro-lyase 1; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress)
Q42560 aminocyclopropanecarboxylate oxidase (EC 1.14.17.4) from Arabidopsis thaliana
PFams: Aconitase, Aconitase_C
898 amino acids: PaperBLAST, CDD (Cluster 1)

ACO3M_ARATH / Q9SIB9 Aconitate hydratase 3, mitochondrial; Aconitase 3; mACO1; Citrate hydro-lyase 3; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress)
Q9SIB9 aconitate hydratase (EC 4.2.1.3) from Arabidopsis thaliana
PFams: Aconitase, Aconitase_C
990 amino acids: PaperBLAST, CDD (Cluster 1)

ACO2M_ARATH / Q94A28 Aconitate hydratase 2, mitochondrial; Aconitase 2; mACO2; Citrate hydro-lyase 2; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Aconitase, Aconitase_C
995 amino acids: PaperBLAST, CDD (Cluster 1)

Bacillus subtilis

ACNA_BACSU / P09339 Aconitate/2-methylaconitate hydratase; Aconitate hydratase A; ACN; Aconitase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.-; EC 4.2.1.3 from Bacillus subtilis (strain 168)
P09339 aconitate hydratase (EC 4.2.1.3) from Bacillus subtilis
PFams: Aconitase, Aconitase_C
909 amino acids: PaperBLAST, CDD (Cluster 1)

Bacteroides fragilis

Q8RP87 aconitate hydratase (EC 4.2.1.3) from Bacteroides fragilis
PFams: Aconitase, Aconitase_C
747 amino acids: PaperBLAST, CDD (Cluster 2)

Bos taurus

ACON_BOVIN / P20004 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine)
PFams: Aconitase, Aconitase_C
780 amino acids: PaperBLAST, CDD (Cluster 2)

Bradyrhizobium diazoefficiens

ACNA_BRADU / P70920 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
PFams: Aconitase, Aconitase_C
906 amino acids: PaperBLAST, CDD (Cluster 1)

Caenorhabditis elegans

ACOC_CAEEL / Q23500 Probable cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Gex-3-interacting protein 22; EC 4.2.1.3 from Caenorhabditis elegans
Q23500 aconitate hydratase (EC 4.2.1.3) from Caenorhabditis elegans
PFams: Aconitase, Aconitase_C
887 amino acids: PaperBLAST, CDD (Cluster 1)

Candida albicans

CH_122731 aconitate hydratase; EC 4.2.1.3 from Candida albicans
PFams: Aconitase, Aconitase_C
777 amino acids: PaperBLAST, CDD (Cluster 2)

Citrus clementina

D3GQL0 aconitate hydratase (EC 4.2.1.3) from Citrus clementina
PFams: Aconitase, Aconitase_C
900 amino acids: PaperBLAST, CDD (Cluster 1)

D3GQL1 aconitate hydratase (EC 4.2.1.3) from Citrus clementina
PFams: Aconitase, Aconitase_C
898 amino acids: PaperBLAST, CDD (Cluster 1)

D3GQL2 aconitate hydratase (EC 4.2.1.3) from Citrus clementina
PFams: Aconitase, Aconitase_C
898 amino acids: PaperBLAST, CDD (Cluster 1)

Corynebacterium glutamicum

ACNA_CORGL / Q8NQ98 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: Aconitase, Aconitase_C
939 amino acids: PaperBLAST, CDD (Cluster 1)

PRPD2_CORGL / Q8NSL3 2-methylcitrate dehydratase 2; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: MmgE_PrpD
504 amino acids: PaperBLAST, CDD (Cluster 5)

Cupriavidus necator

PRPD_CUPNE / Q937N6 2-methylcitrate dehydratase; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha)
PFams: MmgE_PrpD
484 amino acids: PaperBLAST, CDD (Cluster 4)

ACNA_CUPNE / Q937N8 Aconitate hydratase A; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha)
PFams: Aconitase, Aconitase_C
869 amino acids: PaperBLAST, CDD (Cluster 1)

Dinoroseobacter shibae

Dshi_2060 Aconitate hydratase (EC 4.2.1.3) from Dinoroseobacter shibae DFL-12
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
930 amino acids: PaperBLAST, CDD (Cluster 3)

Drosophila melanogaster

Q9NFX2 aconitate hydratase (EC 4.2.1.3) from Drosophila melanogaster
PFams: Aconitase, Aconitase_C
899 amino acids: PaperBLAST, CDD (Cluster 1)

Q9NFX3 aconitate hydratase (EC 4.2.1.3) from Drosophila melanogaster
PFams: Aconitase, Aconitase_C
902 amino acids: PaperBLAST, CDD (Cluster 1)

Emericella nidulans

ACON_EMENI / C8VG90 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; Homocitrate dehydratase; EC 4.2.1.3; EC 4.2.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
PFams: Aconitase, Aconitase_C
783 amino acids: PaperBLAST, CDD (Cluster 1)

Escherichia coli

b1276 aconitate hydratase 1 from Escherichia coli K-12 substr. MG1655
P25516 aconitate hydratase 1 from Escherichia coli (strain K12)
ACNA_ECOLI / P25516 Aconitate hydratase A; ACN; Aconitase; Iron-responsive protein-like; IRP-like; RNA-binding protein; Stationary phase enzyme; EC 4.2.1.3 from Escherichia coli (strain K12)
P25516 aconitate hydratase (EC 4.2.1.3) from Escherichia coli
CH_002745 aconitate hydratase 1; EC 4.2.1.3 from Escherichia coli K12
PFams: Aconitase, Aconitase_C
891 amino acids: PaperBLAST, CDD (Cluster 1)

b0118 AcnB (EC 4.2.1.99) from Escherichia coli K-12 substr. MG1655
P36683 AcnB (EC 4.2.1.99) from Escherichia coli (strain K12)
ACNB_ECOLI / P36683 Aconitate hydratase B; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; 2-methyl-cis-aconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Escherichia coli (strain K12)
P36683 aconitate hydratase (EC 4.2.1.3) from Escherichia coli
GB|AAZ86920.1 aconitate hydratas; EC 4.2.1.3 from Escherichia coli
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
865 amino acids: PaperBLAST, CDD (Cluster 3)

b0334 2-methylcitrate dehydratase (EC 4.2.1.79) from Escherichia coli K-12 substr. MG1655
P77243 2-methylcitrate dehydratase (EC 4.2.1.79) from Escherichia coli (strain K12)
PRPD_ECOLI / P77243 2-methylcitrate dehydratase; 2-MC dehydratase; (2S,3S)-2-methylcitrate dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Escherichia coli (strain K12)
P77243 2-methylcitrate dehydratase (EC 4.2.1.79) from Escherichia coli
PDB|1SZQ 2-methylcitrate dehydratase; EC 4.2.1.79 from Escherichia coli K12
PFams: MmgE_PrpD
483 amino acids: PaperBLAST, CDD (Cluster 4)

Helicobacter pylori

A0A2X5AHR8 aconitate hydratase (EC 4.2.1.3) from Helicobacter pylori
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
852 amino acids: PaperBLAST, CDD (Cluster 3)

P56418 aconitase (EC 4.2.1.3) from Helicobacter pylori (strain ATCC 700392 / 26695)
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
852 amino acids: PaperBLAST, CDD (Cluster 3)

Homo sapiens

P21399 cytoplasmic aconitate hydratase from Homo sapiens
ACOC_HUMAN / P21399 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human)
P21399 aconitate hydratase (EC 4.2.1.3) from Homo sapiens
PFams: Aconitase, Aconitase_C
889 amino acids: PaperBLAST, CDD (Cluster 1)

Q99798 mitochondrial aconitate hydratase from Homo sapiens
ACON_HUMAN / Q99798 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Homo sapiens (Human)
Q99798 aconitate hydratase (EC 4.2.1.3) from Homo sapiens
PFams: Aconitase, Aconitase_C
780 amino acids: PaperBLAST, CDD (Cluster 2)

IREB2_HUMAN / P48200 Iron-responsive element-binding protein 2; IRE-BP 2; Iron regulatory protein 2; IRP2 (from HMM only) from Homo sapiens (Human)
PFams: Aconitase, Aconitase, Aconitase_C
963 amino acids: PaperBLAST, CDD (Cluster 1)

Kitasatospora phosalacinea

A0A0M3N196 phosphinomethylmalate isomerase (EC 4.2.1.166) (from HMM only) from Kitasatospora phosalacinea
PFams: Aconitase, Aconitase_C
882 amino acids: PaperBLAST, CDD (Cluster 1)

Legionella pneumophila

ACON_LEGPH / P37032 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; IP210; Iron-responsive protein-like; IRP-like; Major iron-containing protein; MICP; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
PFams: Aconitase, Aconitase_C
891 amino acids: PaperBLAST, CDD (Cluster 1)

Marinobacter adhaerens

HP15_3433 Aconitate hydratase (EC 4.2.1.3) from Marinobacter adhaerens HP15
PFams: Aconitase, Aconitase_C
919 amino acids: PaperBLAST, CDD (Cluster 1)

Mus musculus

P28271 aconitate hydratase (EC 4.2.1.3) from Mus musculus
PFams: Aconitase, Aconitase_C
889 amino acids: PaperBLAST, CDD (Cluster 1)

Q99KI0 aconitate hydratase (EC 4.2.1.3) from Mus musculus
PFams: Aconitase, Aconitase_C
780 amino acids: PaperBLAST, CDD (Cluster 1)

IREB2_MOUSE / Q811J3 Iron-responsive element-binding protein 2; IRE-BP 2; Iron regulatory protein 2; IRP2 (from HMM only) from Mus musculus (Mouse)
PFams: Aconitase, Aconitase, Aconitase_C
963 amino acids: PaperBLAST, CDD (Cluster 1)

Mycobacterium tuberculosis

PRPD_MYCTE / H8F0D6 2-methylcitrate dehydratase; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
PFams: MmgE_PrpD
505 amino acids: PaperBLAST, CDD (Cluster 5)

PRPD_MYCTU / O06582 2-methylcitrate dehydratase; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: MmgE_PrpD
526 amino acids: PaperBLAST, CDD (Cluster 5)

O53166 aconitase from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
ACNA_MYCTU / O53166 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: Aconitase, Aconitase_C
943 amino acids: PaperBLAST, CDD (Cluster 1)

Neosartorya fumigata

ACON_ASPFU / Q4WLN1 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; Homocitrate dehydratase; EC 4.2.1.3; EC 4.2.1.- from Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
PFams: Aconitase, Aconitase_C
787 amino acids: PaperBLAST, CDD (Cluster 1)

Rattus norvegicus

Q63270 aconitate hydratase (EC 4.2.1.3) from Rattus norvegicus
PFams: Aconitase, Aconitase_C
889 amino acids: PaperBLAST, CDD (Cluster 1)

Q9ER34 aconitate hydratase (EC 4.2.1.3) from Rattus norvegicus
PFams: Aconitase, Aconitase_C
780 amino acids: PaperBLAST, CDD (Cluster 2)

Saccharomyces cerevisiae

ACON_YEAST / P19414 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P19414 aconitate hydratase (EC 4.2.1.3) from Saccharomyces cerevisiae
PFams: Aconitase, Aconitase_C
778 amino acids: PaperBLAST, CDD (Cluster 2)

Salmonella enterica

P74840 2-methylcitrate dehydratase (EC 4.2.1.79) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PRPD_SALTY / P74840 2-methylcitrate dehydratase; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P74840 2-methylcitrate dehydratase (EC 4.2.1.79) from Salmonella enterica
PFams: MmgE_PrpD
483 amino acids: PaperBLAST, CDD (Cluster 4)

Salmonella typhimurium

Q8ZP52 aconitate hydratase 1 (EC 4.2.1.99) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
ACNA_SALTY / Q8ZP52 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; 2-methyl-cis-aconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aconitase, Aconitase_C
891 amino acids: PaperBLAST, CDD (Cluster 1)

Q8ZRS8 aconitate hydratase 2 (EC 4.2.1.99) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
ACNB_SALTY / Q8ZRS8 Aconitate hydratase B; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; 2-methyl-cis-aconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
865 amino acids: PaperBLAST, CDD (Cluster 3)

Schizosaccharomyces pombe

ACON2_SCHPO / Q9P7D4 Homocitrate dehydratase, mitochondrial; Aconitase 2; EC 4.2.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Q9P7D4 aconitate hydratase (EC 4.2.1.3) from Schizosaccharomyces pombe
PFams: Aconitase, Aconitase_C, Ribosomal_L21p
918 amino acids: PaperBLAST, CDD (Cluster 2)

ACON_SCHPO / O13966 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
PFams: Aconitase, Aconitase_C
789 amino acids: PaperBLAST, CDD (Cluster 2)

Shewanella oneidensis

ACND_SHEON / Q8EJW3 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming); Aconitate hydratase; ACN; Aconitase; EC 4.2.1.117; EC 4.2.1.3 from Shewanella oneidensis (strain MR-1)
Q8EJW3 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) (EC 4.2.1.117) from Shewanella oneidensis
PFams: Aconitase, Aconitase_C
867 amino acids: PaperBLAST, CDD (Cluster 1)

Streptomyces viridochromogenes

Q4JFF1 phosphinomethylmalate isomerase (EC 4.2.1.166) (from HMM only) from Streptomyces viridochromogenes
PFams: Aconitase, Aconitase_C
889 amino acids: PaperBLAST, CDD (Cluster 1)

Q9RIL1 aconitate hydratase (EC 4.2.1.3) from Streptomyces viridochromogenes
PFams: Aconitase, Aconitase_C
931 amino acids: PaperBLAST, CDD (Cluster 1)

Sus scrofa

ACON_PIG / P16276 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig)
PFams: Aconitase, Aconitase_C
781 amino acids: PaperBLAST, CDD (Cluster 1)

Thermus thermophilus

ACNA_THET8 / Q5SMF6 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
PFams: Aconitase, Aconitase_C
902 amino acids: PaperBLAST, CDD (Cluster 1)