Other Characterized Proteins Similar to citrullinase

Finding the characterized proteins for citrullinase (putative citrullinase) in L-citrulline catabolism

Or see clustering for step citrullinase

Or see all steps for L-citrulline catabolism

Or cluster curated proteins matching a keyword

Definition of citrullinase

• Curated proteins or TIGRFams with EC 3.5.1.20
• UniProt sequence Q5NHL7_FRATT: SubName: Full=Carbon-nitrogen hydrolase family protein {ECO:0000313|EMBL:CAG45068.1}; EC=3.5.-.- {ECO:0000313|EMBL:CAG45068.1};
• Curated sequence GFF1616: arginine deiminase (EC 3.5.3.6)
• Curated sequence AO353_25635: arginine deiminase (EC 3.5.3.6)
• Curated sequence GFF3434: arginine deiminase (EC 3.5.3.6)
• Comment: The characterized enzyme hydrolyzes citrulline to ornithine, carbon dioxide, and ammonia (FTT0435 or FTT_0435 or Q5NHL7_FRATT; PMID:19502406). Genetic evidence from diverse bacteria shows that a family of putative hydrolases is involved in ornithine utilization: PGA1_c16380 (GFF1616) from Phaeobacter inhibens; AO353_25635 from Pseudomonas fluorescens FW300-N2E3, and PS417_17580 (GFF3434) from Pseudomonas simiae WCS417. These are distantly related to arginine deiminases and were originally reannotated as such (operating in reverse), but Equilibrator predicts that the reverse reaction is thermodynamically very unfavorable. Also, the guanidino-binding residues are not conserved. They are probably citrullinases.

Fetched 4 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 4 other characterized sequences. (Found 7 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for citrullinase.)

AGUB_SOLLC / Q9XGI9 N-carbamoylputrescine amidase; EC 3.5.1.53 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
PFams: CN_hydrolase
300 amino acids: PaperBLAST, CDD, SwissProt::Q9XGI9
51% identical to

Q5NHL7_FRATT Carbon-nitrogen hydrolase family protein; EC=3.5.-.-
286 amino acids: PaperBLAST, CDD

Q8VYF5 At2g27450-monomer (EC 3.5.1.53) from Arabidopsis thaliana
NILP1_ARATH / Q8VYF5 N-carbamoylputrescine amidase; Nitrilase-like protein 1; EC 3.5.1.53 from Arabidopsis thaliana (Mouse-ear cress)
PFams: CN_hydrolase
299 amino acids: PaperBLAST, CDD, SwissProt::Q8VYF5
50% identical to

Q5NHL7_FRATT Carbon-nitrogen hydrolase family protein; EC=3.5.-.-
286 amino acids: PaperBLAST, CDD

Q5KR04 N-carbamoylputrescine amidase (EC 3.5.1.53) from Selenomonas ruminantium
PFams: CN_hydrolase
290 amino acids: PaperBLAST, CDD, BRENDA::Q5KR04
46% identical to

Q5NHL7_FRATT Carbon-nitrogen hydrolase family protein; EC=3.5.-.-
286 amino acids: PaperBLAST, CDD

Q89413 agmatine deiminase (EC 3.5.3.12) from Chlorella virus
PFams: CN_hydrolase
298 amino acids: PaperBLAST, CDD, BRENDA::Q89413
43% identical to

Q5NHL7_FRATT Carbon-nitrogen hydrolase family protein; EC=3.5.-.-
286 amino acids: PaperBLAST, CDD