GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for deoD (deoxyinosine phosphorylase) in 2'-deoxyinosine catabolism

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Definition of deoD

Fetched 26 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 25 of these sequences

Found 3 clusters of similar sequences. Another 2 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 274-315 amino acids (not heteromeric)

PNPH_HUMAN / P00491 Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Homo sapiens (Human)
P00491 purine-nucleoside phosphorylase (EC 2.4.2.1) from Homo sapiens
P00491 purine nucleoside phosphorylase subunit (EC 2.4.2.1; EC 2.4.2.15) from Homo sapiens
PFams: PNP_UDP_1
289 amino acids: PaperBLAST, CDD, Compare to cluster

PNPH_BOVIN / P55859 Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Bos taurus (Bovine)
P55859 purine-nucleoside phosphorylase (EC 2.4.2.1) from Bos taurus
PFams: PNP_UDP_1
289 amino acids: PaperBLAST, CDD, Compare to cluster

Q9BMI9 purine-nucleoside phosphorylase (EC 2.4.2.1) from Schistosoma mansoni
PFams: PNP_UDP_1
287 amino acids: PaperBLAST, CDD, Compare to cluster

PNPH_MOUSE / P23492 Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Mus musculus (Mouse)
PFams: PNP_UDP_1
289 amino acids: PaperBLAST, CDD, Compare to cluster

b2407 xanthosine phosphorylase (EC 2.4.2.1; EC 2.4.2.15) from Escherichia coli K-12 substr. MG1655
XAPA_ECOLI / P45563 Purine nucleoside phosphorylase 2; Inosine-guanosine phosphorylase; Purine nucleoside phosphorylase II; PNP II; Xanthosine phosphorylase; EC 2.4.2.1 from Escherichia coli (strain K12)
P45563 xanthosine phosphorylase (EC 2.4.2.1; EC 2.4.2.15) from Escherichia coli (strain K12)
PFams: PNP_UDP_1
277 amino acids: PaperBLAST, CDD, Compare to cluster

PUNA_GEOSE / P77834 Purine nucleoside phosphorylase 1; PNP 1; Inosine phosphorylase; Inosine-guanosine phosphorylase; Purine nucleoside phosphorylase I; PNP I; Pu-NPase I; EC 2.4.2.1 from Geobacillus stearothermophilus (Bacillus stearothermophilus)
PFams: PNP_UDP_1
274 amino acids: PaperBLAST, CDD, Compare to cluster

PUNA_CELSP / P81989 Purine nucleoside phosphorylase; PNP; Pu-NPase; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Cellulomonas sp.
P81989 purine-nucleoside phosphorylase (EC 2.4.2.1) from Cellulomonas sp.
PFams: PNP_UDP_1
282 amino acids: PaperBLAST, CDD, Compare to cluster

PNPH_RAT / P85973 Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Rattus norvegicus (Rat)
PFams: PNP_UDP_1
289 amino acids: PaperBLAST, CDD, Compare to cluster

PNPH_YEAST / Q05788 Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: PNP_UDP_1
311 amino acids: PaperBLAST, CDD, Compare to cluster

PNPH_SCHPO / Q9UTG1 Putative purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
PFams: PNP_UDP_1
315 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 233-247 amino acids (not heteromeric)

Q72IR2 purine-nucleoside phosphorylase (EC 2.4.2.1) from Thermus thermophilus
PFams: PNP_UDP_1
235 amino acids: PaperBLAST, CDD, Compare to cluster

C8CPR9 purine-nucleoside phosphorylase (EC 2.4.2.1) from Pseudoalteromonas sp.
PFams: PNP_UDP_1
233 amino acids: PaperBLAST, CDD, Compare to cluster

O34925 purine-nucleoside phosphorylase (EC 2.4.2.1) from Bacillus subtilis
PFams: PNP_UDP_1
233 amino acids: PaperBLAST, CDD, Compare to cluster

b4384 purine nucleoside phosphorylase (EC 2.4.2.15; EC 2.4.2.1) from Escherichia coli K-12 substr. MG1655
DEOD_ECOLI / P0ABP8 Purine nucleoside phosphorylase DeoD-type; PNP; Inosine phosphorylase; EC 2.4.2.1 from Escherichia coli (strain K12)
P0ABP8 purine-nucleoside phosphorylase (EC 2.4.2.1) from Escherichia coli
P0ABP8 purine nucleoside phosphorylase (EC 2.4.2.15; EC 2.4.2.1) from Escherichia coli (strain K12)
RF|NP_418801 purine nucleoside phosphorylase deoD-type; EC 2.4.2.1 from Escherichia coli K12
PFams: PNP_UDP_1
239 amino acids: PaperBLAST, CDD, Compare to cluster

PNPH_SACS2 / P50389 Purine nucleoside phosphorylase; PNP; 5'-methylthioadenosine phosphorylase I; MTA phosphorylase I; MTAPI; EC 2.4.2.1; EC 2.4.2.28 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
P50389 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Saccharolobus solfataricus
PFams: PNP_UDP_1
236 amino acids: PaperBLAST, CDD, Compare to cluster

Q9YDC0 purine-nucleoside phosphorylase (EC 2.4.2.1) from Aeropyrum pernix
PFams: PNP_UDP_1
244 amino acids: PaperBLAST, CDD, Compare to cluster

CH_021833 purine nucleoside phosphorylase; EC 2.4.2.1 from Bacillus anthracis
PFams: PNP_UDP_1
235 amino acids: PaperBLAST, CDD, Compare to cluster

Q2HXR2 purine-nucleoside phosphorylase (EC 2.4.2.1) from Toxoplasma gondii
CH_023932 purine nucleoside phosphorylase; EC 2.4.2.1 from Toxoplasma gondii
PFams: PNP_UDP_1
247 amino acids: PaperBLAST, CDD, Compare to cluster

DEOD_MYCGE / P47295 Purine nucleoside phosphorylase DeoD-type; PNP; EC 2.4.2.1 from Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
PFams: PNP_UDP_1
238 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 257-299 amino acids (not heteromeric)

PNPH_PYRFU / Q8U2I1 Probable 6-oxopurine nucleoside phosphorylase; Purine nucleoside phosphorylase; PNP; PfPNP; EC 2.4.2.1 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Q8U2I1 purine-nucleoside phosphorylase (EC 2.4.2.1) from Pyrococcus furiosus
PFams: PNP_UDP_1
265 amino acids: PaperBLAST, CDD, Compare to cluster

MTAP_SACS2 / Q97W94 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPII; EC 2.4.2.28 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Q97W94 purine-nucleoside phosphorylase (EC 2.4.2.1); S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Saccharolobus solfataricus
PFams: PNP_UDP_1
270 amino acids: PaperBLAST, CDD, Compare to cluster

B0L7E7 purine-nucleoside phosphorylase (EC 2.4.2.1) from Salinispora tropica
B0L7E7 chloro-purine nucleoside phosphorylase (EC 2.4.2.1) from Salinispora tropica
PFams: PNP_UDP_1
267 amino acids: PaperBLAST, CDD, Compare to cluster

Q1EMV9 5'-fluoro-5'-deoxy-adenosine phosphorylase (EC 2.4.2.1) from Streptomyces cattleya
PFams: PNP_UDP_1
299 amino acids: PaperBLAST, CDD, Compare to cluster

Q5JEQ6 adenosine phosphorylase (EC 2.4.2.1) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
PFams: PNP_UDP_1
257 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/2 heteromeric)

Q8I3X4 purine-nucleoside phosphorylase (EC 2.4.2.1); uridine phosphorylase (EC 2.4.2.3) from Plasmodium falciparum
Q8T9Z7 purine-nucleoside phosphorylase (EC 2.4.2.1) from Plasmodium falciparum
Q8T9Z7 purine nucleoside phosphorylase monomer (EC 2.4.2.44; EC 2.4.2.1) from Plasmodium falciparum
PFams: PNP_UDP_1
245 amino acids: PaperBLAST, CDD
(similar to BRENDA::P0ABP8 from Cluster 2, but similarity to seed sequence is below thresholds)

b0391 nucleoside phosphorylase PpnP (EC 2.4.2.15; EC 2.4.2.1; EC 2.4.2.2; EC 2.4.2.4; EC 2.4.2.3) from Escherichia coli K-12 substr. MG1655
PPNP_ECOLI / P0C037 Pyrimidine/purine nucleoside phosphorylase; Adenosine phosphorylase; Cytidine phosphorylase; Guanosine phosphorylase; Inosine phosphorylase; Thymidine phosphorylase; Uridine phosphorylase; Xanthosine phosphorylase; EC 2.4.2.1; EC 2.4.2.2; EC 2.4.2.15; EC 2.4.2.4; EC 2.4.2.3 from Escherichia coli (strain K12)
P0C037 nucleoside phosphorylase PpnP (EC 2.4.2.15; EC 2.4.2.2; EC 2.4.2.1) from Escherichia coli (strain K12)
PFams: Ppnp
94 amino acids: PaperBLAST, CDD