Other Characterized Proteins Similar to deoD

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to deoD

Finding the characterized proteins for deoD (deoxyinosine phosphorylase) in 2'-deoxyinosine catabolism

Or see clustering for step deoD

Or see all steps for 2'-deoxyinosine catabolism

Or cluster curated proteins matching a keyword

Definition of deoD

Curated proteins or TIGRFams with EC 2.4.2.1
Ignore hits to items matching 2.4.2.15 when looking for 'other' hits
Comment: The phosphorylase produces 2-deoxy-alpha-D-ribose 1-phosphate (2.4.2.1 includes activity on purine nucleosides and deoxynucleosides) Ignore hits to guanosine phosphorylase (EC 2.4.2.15), which is a quite similar reaction

Fetched 26 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 15 other characterized sequences. (Found 41 hits including self hits.)

Removing ignored items reduces this to 14 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for deoD.)

MTAP_PYRFU / Q8U4Q8 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; PfMTAP; EC 2.4.2.28 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Q8U4Q8 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Pyrococcus furiosus
PFams: PNP_UDP_1
257 amino acids: PaperBLAST, CDD, BRENDA::Q8U4Q8
88% identical to

Q5JEQ6 adenosine phosphorylase (EC 2.4.2.1) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
PFams: PNP_UDP_1
257 amino acids: PaperBLAST, CDD

MTAP_MYCTU / O06401 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; EC 2.4.2.28 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
O06401 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Mycobacterium tuberculosis
PFams: PNP_UDP_1
264 amino acids: PaperBLAST, CDD, BRENDA::O06401
54% identical to

B0L7E7 chloro-purine nucleoside phosphorylase (EC 2.4.2.1) from Salinispora tropica
B0L7E7 purine-nucleoside phosphorylase (EC 2.4.2.1) from Salinispora tropica
PFams: PNP_UDP_1
267 amino acids: PaperBLAST, CDD

MTAP_MYCS2 / A0QR54 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; EC 2.4.2.28 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
PFams: PNP_UDP_1
259 amino acids: PaperBLAST, CDD, SwissProt::A0QR54
57% identical to

Q13126 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Homo sapiens
MTAP_HUMAN / Q13126 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPase; EC 2.4.2.28 from Homo sapiens (Human)
Q13126 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Homo sapiens
PFams: PNP_UDP_1
283 amino acids: PaperBLAST, CDD, BRENDA::Q13126
49% identical to

Q5JEQ6 adenosine phosphorylase (EC 2.4.2.1) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
PFams: PNP_UDP_1
257 amino acids: PaperBLAST, CDD

Q9CQ65 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Mus musculus
PFams: PNP_UDP_1
283 amino acids: PaperBLAST, CDD, BRENDA::Q9CQ65
49% identical to

MTAP_SACS2 / Q97W94 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPII; EC 2.4.2.28 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Q97W94 purine-nucleoside phosphorylase (EC 2.4.2.1); S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Saccharolobus solfataricus
PFams: PNP_UDP_1
270 amino acids: PaperBLAST, CDD

MTAP_BOVIN / Q3MHF7 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPase; EC 2.4.2.28 from Bos taurus (Bovine)
PFams: PNP_UDP_1
283 amino acids: PaperBLAST, CDD, SwissProt::Q3MHF7
48% identical to

C6KFA4 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from uncultured bacterium
PFams: PNP_UDP_1
297 amino acids: PaperBLAST, CDD, BRENDA::C6KFA4
49% identical to

Q5JEQ6 adenosine phosphorylase (EC 2.4.2.1) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
PFams: PNP_UDP_1
257 amino acids: PaperBLAST, CDD

MTAP_RHORT / Q2RXH9 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; EC 2.4.2.28 from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
PFams: PNP_UDP_1
294 amino acids: PaperBLAST, CDD, SwissProt::Q2RXH9
45% identical to

MTAP_DROME / Q9V813 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPase; EC 2.4.2.28 from Drosophila melanogaster (Fruit fly)
PFams: PNP_UDP_1
289 amino acids: PaperBLAST, CDD, SwissProt::Q9V813
44% identical to

Q5JEQ6 adenosine phosphorylase (EC 2.4.2.1) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
PFams: PNP_UDP_1
257 amino acids: PaperBLAST, CDD

Q9YA34 uridine phosphorylase (EC 2.4.2.3) from Aeropyrum pernix
PFams: PNP_UDP_1
282 amino acids: PaperBLAST, CDD, BRENDA::Q9YA34
43% identical to

Q72IR2 purine-nucleoside phosphorylase (EC 2.4.2.1) from Thermus thermophilus
PFams: PNP_UDP_1
235 amino acids: PaperBLAST, CDD

MTAP_SCHPO / Q09816 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPase; EC 2.4.2.28 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
PFams: PNP_UDP_1
307 amino acids: PaperBLAST, CDD, SwissProt::Q09816
42% identical to

Q5JJC1 uridine phosphorylase (EC 2.4.2.2) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
PFams: PNP_UDP_1
277 amino acids: PaperBLAST, CDD, metacyc::MONOMER-19659
40% identical to

Q72IR2 purine-nucleoside phosphorylase (EC 2.4.2.1) from Thermus thermophilus
PFams: PNP_UDP_1
235 amino acids: PaperBLAST, CDD

MTAP_YEAST / Q07938 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPase; Multicopy enhancer of UAS2; EC 2.4.2.28 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: PNP_UDP_1
337 amino acids: PaperBLAST, CDD, SwissProt::Q07938
40% identical to

Q5JEQ6 adenosine phosphorylase (EC 2.4.2.1) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
PFams: PNP_UDP_1
257 amino acids: PaperBLAST, CDD

Q9HZK1 S-methyl-5'-thioinosine phosphorylase monomer (EC 2.4.2.44) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
MTIP_PSEAE / Q9HZK1 S-methyl-5'-thioinosine phosphorylase; 5'-methylthioinosine phosphorylase; MTI phosphorylase; MTIP; EC 2.4.2.44 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9HZK1 S-methyl-5'-thioinosine phosphorylase (EC 2.4.2.44) from Pseudomonas aeruginosa
PFams: PNP_UDP_1
245 amino acids: PaperBLAST, CDD, BRENDA::Q9HZK1
40% identical to

PNPH_PYRFU / Q8U2I1 Probable 6-oxopurine nucleoside phosphorylase; Purine nucleoside phosphorylase; PNP; PfPNP; EC 2.4.2.1 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Q8U2I1 purine-nucleoside phosphorylase (EC 2.4.2.1) from Pyrococcus furiosus
PFams: PNP_UDP_1
265 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for deoD.)

Q5JJB8 guanosine phosphorylase (EC 2.4.2.15) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
PFams: PNP_UDP_1
267 amino acids: PaperBLAST, CDD, metacyc::MONOMER-19658
76% identical to