GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to THT2A

Finding the characterized proteins for THT2A (fructose THT2A) in D-fructose catabolism

Or see clustering for step THT2A

Or see all steps for D-fructose catabolism

Or cluster curated proteins matching a keyword

Definition of THT2A

Fetched 1 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 3 other characterized sequences. (Found 4 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for THT2A.)

TC 2.A.1.1.76 / O76486 Glucose transporter, GT1. GT1, 2, and 3 are homologues. GT2 and GT3 transport ribose as well as glucose at different rates. GT3 transports ribose with 6-fold lower efficiency due to two threonines in GT3 that are alanines in GT2. They are in two loops between TMSs 3, 4, and 7, 8 (Naula et al., 2010). GT1 is expressed in the flagellar membrane and may be both a glucose transporter and sensor, allowing the parasites to enter the stationary phase when they deplete glucose although in the absence of the sensor, they lose viability from Leishmania mexicana
PFams: Sugar_tr, MFS_1, Sugar_tr
610 amino acids: PaperBLAST, CDD, TCDB::O76486
46% identical to

TC 2.A.1.1.18 / Q06222 Glucose/mannose/fructose transporter and high affinity sensor, Snf3p (regulates glucose transport via other systems) from Trypanosoma brucei brucei
PFams: Sugar_tr, MFS_1
529 amino acids: PaperBLAST, CDD

TC 2.A.1.1.78 / O61060 The glucose transporter, LmGT3 (homologous to LmGT2 (1.A.1.1.75)). Two threonine residues located in the hydrophilic loops connecting TMSs 3 & 4 and 7 & 8 of GT3 prevent transport of D-ribose. Changing these two residues to alanine (as in GT2) allows transport of ribose. Thus, loops 3-4 and 7-8 partially determine substrate specificity from Leishmania mexicana
PFams: Sugar_tr, MFS_1, Sugar_tr
566 amino acids: PaperBLAST, CDD, TCDB::O61060
47% identical to

TC 2.A.1.1.18 / Q06222 Glucose/mannose/fructose transporter and high affinity sensor, Snf3p (regulates glucose transport via other systems) from Trypanosoma brucei brucei
PFams: Sugar_tr, MFS_1
529 amino acids: PaperBLAST, CDD

TC 2.A.1.1.77 / O61059 The D-glucose/D-ribose transporter, LmGT2 (Most similar to 1.A.1.1.18) from Leishmania mexicana
PFams: Sugar_tr, MFS_1, Sugar_tr
567 amino acids: PaperBLAST, CDD, TCDB::O61059
47% identical to

TC 2.A.1.1.18 / Q06222 Glucose/mannose/fructose transporter and high affinity sensor, Snf3p (regulates glucose transport via other systems) from Trypanosoma brucei brucei
PFams: Sugar_tr, MFS_1
529 amino acids: PaperBLAST, CDD