Other Characterized Proteins Similar to fucDH

Finding the characterized proteins for fucDH (2-keto-3-deoxy-L-fuconate 4-dehydrogenase) in L-fucose catabolism

Or see clustering for step fucDH

Or see all steps for L-fucose catabolism

Or cluster curated proteins matching a keyword

Definition of fucDH

• Curated sequence Q8P3K4: 2-keto-3-deoxy-L-fuconate dehydrogenase; EC 1.1.1.-
• UniProt sequence A0A4P7ABK7: SubName: Full=SDR family oxidoreductase {ECO:0000313|EMBL:QBP77113.1};
• UniProt sequence D8IS13: SubName: Full=Short-chain alcohol dehydrogenase protein {ECO:0000313|EMBL:ADJ65356.1};
• UniProt sequence B2T9V3: SubName: Full=Short-chain dehydrogenase/reductase SDR {ECO:0000313|EMBL:ACD21205.1};
• Comment: No EC number, but XCC4067 (Q8P3K4) is annotated in SwissProt based on PMID:17144652. C785_RS13675 (A0A4P7ABK7) was also shown to have this acivity (PMC6336799) HSERO_RS19365 (D8IS13) and BPHYT_RS34215 (B2T9V3) are important for fucose utilization (The substrate for EC 1.1.1.401 (2-dehydro-3-deoxy-L-rhamnonate 4-dehydrogenase) has the other stereochemistry at position 4.)

Fetched 4 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 5 other characterized sequences. (Found 6 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for fucDH.)

BDH2_MOUSE / Q8JZV9 3-hydroxybutyrate dehydrogenase type 2; Dehydrogenase/reductase SDR family member 6; R-beta-hydroxybutyrate dehydrogenase; EC 1.1.1.-; EC 1.1.1.30 from Mus musculus (Mouse)
Q8JZV9 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Mus musculus
PFams: adh_short, KR, adh_short_C2
245 amino acids: PaperBLAST, CDD, SwissProt::Q8JZV9
57% identical to

D8IS13 Short-chain alcohol dehydrogenase protein
254 amino acids: PaperBLAST, CDD

Q9BUT1 3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.30) from Homo sapiens
BDH2_HUMAN / Q9BUT1 3-hydroxybutyrate dehydrogenase type 2; Dehydrogenase/reductase SDR family member 6; Oxidoreductase UCPA; R-beta-hydroxybutyrate dehydrogenase; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30 from Homo sapiens (Human)
PFams: adh_short, KR, adh_short_C2
245 amino acids: PaperBLAST, CDD, SwissProt::Q9BUT1
56% identical to

B2T9V3 Short-chain dehydrogenase/reductase SDR
247 amino acids: PaperBLAST, CDD

BDH2_DANRE / Q561X9 3-hydroxybutyrate dehydrogenase type 2; R-beta-hydroxybutyrate dehydrogenase; EC 1.1.1.-; EC 1.1.1.30 from Danio rerio (Zebrafish) (Brachydanio rerio)
Q561X9 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Danio rerio
PFams: adh_short, adh_short_C2
245 amino acids: PaperBLAST, CDD, BRENDA::Q561X9
54% identical to

B2T9V3 Short-chain dehydrogenase/reductase SDR
247 amino acids: PaperBLAST, CDD

b2426 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli K-12 substr. MG1655
P37440 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli (strain K12)
PFams: adh_short, KR, adh_short_C2
263 amino acids: PaperBLAST, CDD, ecocyc::EG12133-MONOMER
41% identical to

B2T9V3 Short-chain dehydrogenase/reductase SDR
247 amino acids: PaperBLAST, CDD

Q56841 2-(S)-hydroxypropyl-CoM dehydrogenase subunit (EC 1.1.1.269) from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)
Q56841 2-(S)-hydroxypropyl-CoM dehydrogenase (EC 1.1.1.269) from Xanthobacter autotrophicus
PFams: adh_short, KR, adh_short_C2
249 amino acids: PaperBLAST, CDD, metacyc::MONOMER-13284
40% identical to

FUCDH_XANCP / Q8P3K4 2-keto-3-deoxy-L-fuconate dehydrogenase; EC 1.1.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
PFams: adh_short, adh_short_C2
300 amino acids: PaperBLAST, CDD