GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to sdcL

Finding the characterized proteins for sdcL (fumarate:Na+ symporter SdcL) in fumarate catabolism

Or see clustering for step sdcL

Or see all steps for fumarate catabolism

Or cluster curated proteins matching a keyword

Definition of sdcL

Fetched 7 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 2 other characterized sequences. (Found 9 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for sdcL.)

S13A5_HUMAN / Q86YT5 Solute carrier family 13 member 5; Na(+)/citrate cotransporter; NaCT; Sodium-coupled citrate transporter; Sodium-dependent citrate transporter from Homo sapiens (Human)
TC 2.A.47.1.9 / Q86YT5 Na+-coupled citrate transporter (NaCT) (Km=20 μM) (also may transport dicarboxylates and other tricarboxylates with lower affinity) (Inoue et al., 2002b; Bergeron et al. 2013). Na+:citrate = 3-4:1 (Bergeron et al. 2013). Na+:citrate = 3-4:1 from Homo sapiens (Human)
PFams: Na_sulph_symp, CitMHS, CitMHS
568 amino acids: PaperBLAST, CDD, SwissProt::Q86YT5
40% identical to

NAD1_CAEEL / Q93655 Sodium-dependent low-affinity dicarboxylate transporter 1; Na(+)/dicarboxylate cotransporter 1; NaDC-1; ceNaDC1 from Caenorhabditis elegans
TC 2.A.47.1.7 / Q93655 Low affinity dicarboxylate:Na+ symporter, NaDC1 (INDY1) (relative affinities: succinate > fumarate > α-ketoglutarate > malate > lactate > maleate)
PFams: Na_sulph_symp, CitMHS, CitMHS
582 amino acids: PaperBLAST, CDD

TC 2.A.47.1.3 / O35055 The brush boarder intestinal and renal electrogenic, Na -dependent, low affinity (0.1-4.0mM), dicarboxylate (succinate, fumarate, malate, α-ketoglutarate, oxaloacetate, L- and D-glutamate, and citrate):H cotransporter, NaDC-1 or SDCT1.  Functions in acid regulation.  An acidic pH  stimullates citrate uptake; acid stimulation is mediated by endothelin-1 (ET-1) and its receptor from Rattus norvegicus (Rat)
PFams: Na_sulph_symp, CitMHS, CitMHS
587 amino acids: PaperBLAST, CDD, TCDB::O35055
40% identical to

NAD1_CAEEL / Q93655 Sodium-dependent low-affinity dicarboxylate transporter 1; Na(+)/dicarboxylate cotransporter 1; NaDC-1; ceNaDC1 from Caenorhabditis elegans
TC 2.A.47.1.7 / Q93655 Low affinity dicarboxylate:Na+ symporter, NaDC1 (INDY1) (relative affinities: succinate > fumarate > α-ketoglutarate > malate > lactate > maleate)
PFams: Na_sulph_symp, CitMHS, CitMHS
582 amino acids: PaperBLAST, CDD