Other Characterized Proteins Similar to galE

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to galE

Finding the characterized proteins for galE (UDP-glucose 4-epimerase) in D-galactose catabolism

Or see clustering for step galE

Or see all steps for D-galactose catabolism

Or cluster curated proteins matching a keyword

Definition of galE

Curated proteins or TIGRFams with EC 5.1.3.2
UniProt sequence L0FXG3: RecName: Full=UDP-glucose 4-epimerase {ECO:0000256|ARBA:ARBA00018569, ECO:0000256|RuleBase:RU366046}; EC=5.1.3.2 {ECO:0000256|ARBA:ARBA00013189, ECO:0000256|RuleBase:RU366046};
Comment: Echvi_1472 (L0FXG3) is important for galactose utilization and similar to E. coli galE

Fetched 54 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 5 other characterized sequences. (Found 58 hits including self hits.)

There are also 13 HMM-only high-coverage hits.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for galE.)

Q9KID0 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Pseudomonas aeruginosa
PFams: Polysacc_synt_2, RmlD_sub_bind, 3Beta_HSD, Epimerase, GDP_Man_Dehyd, NAD_binding_4, NAD_binding_10, Polysacc_syn_2C
344 amino acids: PaperBLAST, CDD, metacyc::MONOMER-18148
65% identical to

CAPD_RICPR / Q9ZDJ5 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Rickettsia prowazekii (strain Madrid E)
PFams: RmlD_sub_bind, Polysacc_synt_2, Epimerase, GDP_Man_Dehyd, NmrA, 3Beta_HSD, NAD_binding_4, NAD_binding_10, Polysacc_syn_2C
341 amino acids: PaperBLAST, CDD

Q8L348 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Vibrio cholerae O37
PFams: RmlD_sub_bind, Polysacc_synt_2, Epimerase, GDP_Man_Dehyd, NmrA, 3Beta_HSD, NAD_binding_4, NAD_binding_10, Polysacc_syn_2C
345 amino acids: PaperBLAST, CDD, metacyc::MONOMER-18161
63% identical to

PSEB_CAMJJ / Q5QKR8 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176)
PFams: RmlD_sub_bind, Epimerase, NmrA, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_10
334 amino acids: PaperBLAST, CDD, SwissProt::Q5QKR8
40% identical to

PSEB_CAMJE / Q0P8W4 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
PFams: RmlD_sub_bind, Epimerase, NmrA, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_10
334 amino acids: PaperBLAST, CDD, SwissProt::Q0P8W4
40% identical to

Q81A42 UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.135) from Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Q81A42 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Bacillus cereus
PFams: Epimerase, KR, NmrA, Polysacc_synt_2, RmlD_sub_bind, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_4, NAD_binding_10
328 amino acids: PaperBLAST, CDD, BRENDA::Q81A42
40% identical to

HMM-only sequences

(Since these sequences' annotations are outside the definition for galE, HMM hits that are over 40% similar to these sequences will be scored as moderate confidence.)

Q9SUN3 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana
PFams: RmlD_sub_bind, Epimerase, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_10
411 amino acids: PaperBLAST, CDD

Q2LC83 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Hordeum vulgare
PFams: RmlD_sub_bind, Epimerase, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_10
421 amino acids: PaperBLAST, CDD

O64749 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana
PFams: RmlD_sub_bind, Epimerase, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_4, NAD_binding_10
417 amino acids: PaperBLAST, CDD

Q2LC81 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Hordeum vulgare
PFams: RmlD_sub_bind, Epimerase, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_4, NAD_binding_10
405 amino acids: PaperBLAST, CDD

CH_123272 UDP-glucose 4-epimerase from Candida albicans
PFams: adh_short, Epimerase, Polysacc_synt_2, RmlD_sub_bind, 3Beta_HSD, GDP_Man_Dehyd, KR, NAD_binding_10, NAD_binding_4, Aldose_epim
675 amino acids: PaperBLAST, CDD

Q92WA3 UDP-xylose 4-epimerase subunit (EC 5.1.3.5) from Rhizobium meliloti (strain 1021)
Q92WA3 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Sinorhizobium meliloti
PFams: RmlD_sub_bind, Epimerase, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_4
328 amino acids: PaperBLAST, CDD

Q7MH46 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Vibrio vulnificus
PFams: RmlD_sub_bind, Epimerase, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, KR
336 amino acids: PaperBLAST, CDD

E5KJ99 UDP-6-deoxy-5,6-ene-GlcNAc 4-epimerase (EC 5.1.3.7) from Streptomyces chartreusis
PFams: RmlD_sub_bind, Epimerase, KR, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_10, NAD_binding_4
327 amino acids: PaperBLAST, CDD

Q9FI17 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana
PFams: RmlD_sub_bind, Epimerase, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_4, NAD_binding_10
436 amino acids: PaperBLAST, CDD

Q8L0V2 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Escherichia coli
PFams: RmlD_sub_bind, Epimerase, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_4
339 amino acids: PaperBLAST, CDD

Q9SA77 UDP-D-xylose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana
ARAE1_ARATH / Q9SA77 UDP-arabinose 4-epimerase 1; UDP-D-xylose 4-epimerase 1; EC 5.1.3.5 from Arabidopsis thaliana (Mouse-ear cress)
Q9SA77 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana
PFams: RmlD_sub_bind, Epimerase, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_4, NAD_binding_10
419 amino acids: PaperBLAST, CDD

Q4KXC7 N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase (EC 5.1.3.26) from Escherichia coli
PFams: RmlD_sub_bind, Epimerase, Polysacc_synt_2, GDP_Man_Dehyd, 3Beta_HSD, NAD_binding_4
339 amino acids: PaperBLAST, CDD

CH_122263 UDP-glucose 4-epimerase (Eurofung) from Emericella nidulans
PFams: KR, Epimerase, Polysacc_synt_2, RmlD_sub_bind, adh_short, 3Beta_HSD, GDP_Man_Dehyd
376 amino acids: PaperBLAST, CDD