Clusters of Characterized Proteins

Clustering the characterized proteins for gntA (gluconate TRAP transporter, small permease component) in D-gluconate catabolism

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Definition of gntA

• UniProt sequence Q930R3: SubName: Full=TRAP-type small permease component {ECO:0000313|EMBL:AAK64790.1};
• UniProt sequence G8AR26: SubName: Full=TRAP dicarboxylate transport system, small permease component (DctQ-like) {ECO:0000313|EMBL:CCC99887.1};
• Curated sequence GFF2080: fusion of gluconokinase and the small permease component of the D-gluconate TRAP transporter
• UniProt sequence A0A165IVI0: SubName: Full=C4-dicarboxylate ABC transporter permease {ECO:0000313|EMBL:KZT13591.1};
• Comment: A TRAP type transporter for gluconate is described in Sinorhizobium meliloti (PMID:19060150). SMa0249 (gntA, Q930R3) is the small permease component. SMa0250 (gntB, Q930R2) is the large permease component. SMa0252 (gntC, Q930R1) is the periplasmic solute-binding component. Fitness data identified related systems in Azospirillum brasilense Sp245, Pseudomona stutzeri RCH2, Acidovorax sp. GW101-3H11. AZOBR_RS15925 = AZOBR_p130075 = G8AR26 is the small permease component; it was originally annotated as a pseudogene. AZOBR_RS15920 is the large permease component. AZOBR_RS15915 = G8AR24 is the solute receptor (DctP-like) . In psRCH2, these are Psest_2123, Psest_2124, Psest_2125 (GFF2080:GFF2082); the small permease component is fused to gluconokinase. In Acidovorax, these are Ac3H11_3228 (A0A165IVI0), Ac3H11_3227 (A0A165IWV9), Ac3H11_3226 (A0A165IVH1).

Fetched 4 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 2 of these sequences

Found 1 clusters of similar sequences. Another 2 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 177-179 amino acids (not heteromeric)

G8AR26 TRAP dicarboxylate transport system, small permease component (DctQ-like)
179 amino acids: PaperBLAST, CDD, Compare to cluster

Q930R3 TRAP-type small permease component
177 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (1/2 heteromeric)

A0A165IVI0 C4-dicarboxylate ABC transporter permease
170 amino acids: PaperBLAST, CDD

Psest_2123 fusion of gluconokinase and the small permease component of the D-gluconate TRAP transporter from Pseudomonas stutzeri RCH2
PFams: AAA_33, SKI, DctQ
Heteromeric, 376 amino acids: PaperBLAST, CDD